[1]刘玉金,张孝军,宋伟祥,等.尿激酶经导管接触溶栓治疗急性肢体缺血初步临床应用 [J].介入放射学杂志,2018,27(03):262-265.
 LIU Yujin,ZHANG Xiaojun,SONG Weixiang,et al.Preliminary clinical application of catheter- directed thrombolysis with urokinase for acute limb ischemia[J].journal interventional radiology,2018,27(03):262-265.
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尿激酶经导管接触溶栓治疗急性肢体缺血初步临床应用 

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年03期
页码:
262-265
栏目:
临床研究
出版日期:
2018-03-25

文章信息/Info

Title:
Preliminary clinical application of catheter- directed thrombolysis with urokinase for acute limb ischemia
作者:
刘玉金 张孝军 宋伟祥 沈旭波 李浏博
Author(s):
LIU Yujin ZHANG Xiaojun SONG Weixiang SHEN Xubo LI Liubo
Department of Interventional Radiology, Affiliated Yueyang Hospital of Integrated Traditional Chinese & Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
关键词:
【关键词】 急性肢体缺血 导管接触溶栓 尿激酶 血栓
文献标志码:
A
摘要:
【摘要】 目的 探讨经导管灌注尿激酶接触溶栓治疗急性肢体缺血的临床效果和安全性。方法 回顾性分析经UniFuse溶栓导管灌注尿激酶治疗21例急性肢体缺血患者临床资料,总结导管接触溶栓(CDT)临床疗效、预后及并发症。结果 全部患者溶栓有效,临床症状缓解,保肢成功。1例因肾功能失代偿发生脑出血死亡,无其它出血、血肿、致残并发症。结论 初步临床研究表明,CDT术治疗急性肢体缺血安全有效,有助于减少不必要的外科手术及支架植入,溶栓风险可控。

参考文献/References:

[1] Smeds MR, Sandhu HK, Leake SS, et al. Patterns in the management of acute limb ischemia: a VESS survey[J]. Ann Vasc Surg, 2017, 38: 164- 171.
[2] Pascoe H, Robertson D. Catheter- directed thrombolysis for acute limb ischaemia: an audit[J]. Australas Med J, 2014, 7: 471- 475.
[3] Ueda T, Murata S, Miki I, et al. Endovascular treatment strategy using catheter- directed thrombolysis, percutaneous aspiration thromboembolectomy, and angioplasty for acute upper limb ischemia[J]. Cardiovasc Intervent Radiol, 2017, 40: 978- 986.
[4] 李麟荪, 滕皋军. 介入放射学临床与并发症[M]. 北京: 人民卫生出版社, 2010.
[5] Gandhi SS, Ewing JA, Cooper E, et al. Comparison of low- dose catheter- directed thrombolysis with and without pharmacome- chanical thrombectomy for acute lower extremity ischemia[J]. Ann Vasc Surg, 2018, 46: 178- 186.
[6] 李孝成, 潘光栋, 肖运平, 等. 导管溶栓治疗急性下肢缺血30例[J]. 介入放射学杂志, 2014, 23: 250- 252.
[7] 李水仙, 郑维红, 庄晓荣, 等. 不同溶栓方法治疗心源性脑栓塞的对比研究[J]. 介入放射学杂志, 2014, 23: 843- 847.
[8] 葛世堂, 袁潘晓, 琳 袁, 等. 机械性血栓抽吸治疗急性下肢动脉栓塞临床效果[J]. 介入放射学杂志, 2015, 24: 954- 956.
[9] Chen YX, Liu CW, Zeng R, et al. Pulse- spray catheter directed thrombolysis in patients with recent onset or deterioration of lower extremity ischemia[J]. Chin Med J(Engl), 2012, 125: 188- 192.
[10] Wong VW, Major MR, Higgins JP. Nonoperative management of acute upper limb ischemia[J]. Hand(N Y), 2016, 11: 131- 143.
[11] Saroukhani A, Ravari H, Pezeshki Rad M. Effects of intravenous and catheter directed thrombolytic therapy with recombinant tissue plasminogen activator(Alteplase) in non- traumatic acute limb ischemia: a randomized double- blind clinical trial[J]. Bull Emerg Trauma, 2015, 3: 86- 92.
[12] Galanakis N, Kontopodis N, Peteinarakis I, et al. Direct stenting in patients with acute lower limb arterial occlusions: immediate and long- term results[J]. Cardiovasc Intervent Radiol, 2017, 40: 192- 201.
[13] Schrijver AM, De Borst GJ, Van Herwaarden JA, et al. Catheter- directed thrombolysis for acute upper extremity ischemia[J]. J Cardiovasc Surg(Torino), 2015, 56: 433- 439.

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备注/Memo

备注/Memo:
(收稿日期:2017-09-05)
(本文编辑:边 佶)
更新日期/Last Update: 2018-03-19