[1]焦德超,庞晨光,韩新巍,等.可携带125I粒子的鼻饲营养管研制及初步临床使用 [J].介入放射学杂志,2017,(11):1004-1008.
 JIAO Dechao,PANG Chenguang,HAN Xinwei,et al.Nasal feeding nutritional tube capable of carrying 125I particles: its preparation and preliminary clinical application[J].journal interventional radiology,2017,(11):1004-1008.
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可携带125I粒子的鼻饲营养管研制及初步临床使用 



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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年11期
页码:
1004-1008
栏目:
非血管介入
出版日期:
2017-11-25

文章信息/Info

Title:
Nasal feeding nutritional tube capable of carrying 125I particles: its preparation and preliminary clinical application
作者:
焦德超 庞晨光 韩新巍 牛荣仿 李宗明 朱 明 路慧彬
Author(s):
JIAO Dechao PANG Chenguang HAN Xinwei NIU Rongfang LI Zongming ZHU Ming LU Huibin
Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, China
关键词:
【关键词】 125I粒子 鼻饲营养 近距离放疗 食管肿瘤
文献标志码:
A
摘要:
【摘要】 目的 设计一种可携带125I粒子的鼻饲营养管,用于治疗上消化道恶性阻塞性病变,以达到鼻饲营养和腔道内近距离放疗的双重效果。方法 将125I放射性粒子置入3 F导管内并两端封闭制成粒子链,使用捆绑技术将粒子链固定于鼻饲管上,并在DSA透视下置入可携125I粒子链的鼻饲营养管,其中粒子链段跨越食管闭塞或狭窄段行近距离放疗。6例晚期食管癌使用该项技术,记录技术成功率,操作时间,并发症。术后2个月评价Karnofsky评分,疼痛视觉模拟评分(VAS),Neuhaus吞咽困难分级,对比剂通畅情况,肿瘤局部情况。结果 可携带125I放射性粒子链的鼻饲营养管制作简单,技术均获成功,平均操作时间15.5 min,无出血、感染等严重并发症。术后2个月Karnofsky评分、VAS评分、Neuhaus吞咽困难分级均较术前明显改善(P<0.01),对比剂通过闭塞狭窄区顺利,肿瘤评价均为部分缓解、局部控制。随访2~6个月,再发梗阻1例。 结论 可携带125I粒子的鼻饲营养管制作简单易行,可同时实现胃肠营养和近距离放疗,为食管恶性肿瘤所致阻塞性病变的治疗开辟了新的途径。

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备注/Memo

备注/Memo:
(收稿日期:2017-02-07)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2017-11-16