[1]肖全平,吴春根,王 涛,等.125I粒子植入联合经皮椎体成形术治疗累及硬膜囊脊椎转移瘤[J].介入放射学杂志,2014,(12):1052-1055.
 XIAO Quan ping,WU Chun gen,WANG Tao,et al.125I seed implantation and percutaneous vertebroplasty for the treatment of spinal metastasis involving dural sac [J].journal interventional radiology,2014,(12):1052-1055.
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125I粒子植入联合经皮椎体成形术治疗累及硬膜囊脊椎转移瘤 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年12期
页码:
1052-1055
栏目:
非血管介入
出版日期:
2014-12-25

文章信息/Info

Title:
125I seed implantation and percutaneous vertebroplasty for the treatment of spinal metastasis involving dural sac
作者:
肖全平 吴春根 王 涛 李明华 程永德
Author(s):
XIAO Quan ping WU Chun gen WANG Tao LI Ming hua CHENG Yong de.
Department of Radiology, the Affiliated Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
关键词:
【关键词】 125I粒子 经皮椎体成形术 累及硬膜囊 脊椎转移瘤
文献标志码:
A
摘要:
【摘要】 目的 探讨125I粒子植入联合经皮椎体成形术(PVP)治疗累及硬膜囊的脊椎转移瘤临床疗效。方法 回顾性分析2012年6月—2013年6月行125I粒子植入及PVP累及硬膜囊的脊椎转移瘤20例患者38节病变椎体。采用视觉模拟评分(VAS)、体力状况评分(KPS)和肿瘤病灶大小(mm3)3方面评价其疗效。分别记录术前VAS、KPS评分;术后24 h, 1、3和6个月VAS及KPS评分;利用图像处理软件计算出术前肿瘤病灶大小、测量术后1、3和6个月残余肿瘤病灶大小,观察肿瘤有无增大。结果 20例患者手术均成功,每个椎体骨水泥平均注射量为(3.8 ± 1.6)ml,每节椎体粒子平均植入量为(35 ± 5)粒。随访6个月 ~ 1年,平均8个月。术前VAS平均得分为7.41 ± 0.79;术后24 h,1、3和6个月VAS平均得分分别降为5.68 ± 0.83、3.91 ± 0.86、3.50 ± 0.90和2.86 ± 0.83;术前KPS平均得分为53.64 ± 11.66; 术后24 h,1、3和6个月KPS平均得分分别为59.32 ± 7.19、80.33 ± 4.32、84.55 ± 5.09和82.05 ± 6.06。术前肿瘤病灶平均大小为(650 ± 10)mm3,术后1、3和6个月残余肿瘤病灶大小分别为(305 ± 9)、(138 ± 10)和(115 ± 7)mm3,术后1、3和6个月肿瘤控制有效率达到70.0%、70.0%和88.9%。结论 125I粒子植入联合PVP治疗累及硬膜囊脊椎转移瘤在技术上可行,可有效控制病灶累及脊髓,保护脊髓神经功能健全。 

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备注/Memo

备注/Memo:
(收稿日期:2014-02-20)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-12-24