[1]徐安辉,漆剑频,王 南.经皮腔内下肢血管成形术前预防性应用抗生素必要性研究 [J].介入放射学杂志,2015,(04):297-300.
 XU An hui,QI Jian pin,WANG Nan.Percutaneous transluminal angioplasty of lower extremity: Is preoperative use of prophylactic antibiotics necessary?[J].journal interventional radiology,2015,(04):297-300.
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经皮腔内下肢血管成形术前预防性应用抗生素必要性研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年04期
页码:
297-300
栏目:
血管介入
出版日期:
2015-04-25

文章信息/Info

Title:
Percutaneous transluminal angioplasty of lower extremity: Is preoperative use of prophylactic antibiotics necessary?
作者:
徐安辉 漆剑频 王 南
Author(s):
XU An hui QI Jian pin WANG Nan
Department of Radiology, Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430030, China
关键词:
抗生素 预防 介入放射学
文献标志码:
A
摘要:
目的 研究经皮腔内血管成形术(PTA)前预防性应用抗生素的必要性。方法 以前瞻性研究方法将86例下肢动脉硬化闭塞症(PAOD)患者(101肢)随机分为观察组和对照组,观察组41例(51肢)于术前2 h内静脉预防性应用抗生素,对照组45例(50肢)不用任何抗生素。比较两组患者术后症状及感染发生情况。结果 两组术后共出现发热27例,其中观察组12例(29.3%),对照组15例(33.3%);观察组和对照组分别有6例(14.7%)和7例(15.6%)中性粒细胞升高(> 70%)。两组间差异无统计学意义(P > 0.05)。两组中各有1例出现败血症,均为老年糖尿病患者。结论 预防性应用抗生素与PTA术后感染发生率没有相关性。对具有感染高危因素患者预防性应用抗生素的价值,还需进一步研究。

参考文献/References:

[1] Ryan JM, Ryan BM, Smith TP. Antibiotic prophylaxis in interventional radiology[J]. J Vasc Interv Radiol, 2004, 15: 547 556.
[2] Gebauer B, El Sheik M, Vogt M, et al. Combined ultrasound and fluoroscopyguided port catheter implantation high success and low complication rate[J]. Eur J Radiol, 2009, 69: 517 522.
[3] Beddy P, Ryan JM. Antibiotic prophylaxis in interventionalradio logy: Anything new[J]. Tech Vasc Interv Radiol, 2006, 9: 69 76.
[4] Ambrose NS, Johnson M, Burdon DW, et al. The influenceof a single dose of intravenous antibiotics on faecal flora and emergenceof Clostridium difficile[J]. J Antimicrob Chemother, 1985, 15: 319 326.
[5] Dancer SJ. The problemwith cephalosporins[J]. J Antimicrob Chemother, 2011, 48: 463 478.
[6] McDermott VG, Schuster MG, Smith TP. Antibiotic prophylaxis in vascular and interventional radiology[J]. AJR Am J Roentgenol, 1997, 169: 31 38.
[7] 倪才方, 狄镇海, 程永德. 介入放射科抗菌药物使用指南(草案)[J]. 介入放射学杂志, 2013, 22: 353 357.
[8] Norgren L, Hiatt WR, Dormandy JA, et al. Inter society consensus for the management of peripheral arterial disease(TASC Ⅱ)[J]. Eur J Vasc Endovasc Surg, 2007, 33 Suppl 1: S1 S75.
[9] Mulvey MR, Simor AE. Antimicrobial resistance in hospitals: how concerned should we be?[J]. CMAJ, 2009, 180: 408 415.
[10] Reddy P, Chadaga S, Noskin GA. Antibiotic considerations in the treatment of multidrug resistant(MDR) pathogens: a case based review[J]. J Hosp Med, 2009, 4: E8 E15.
[11] Moon E, Tam MD, Kikano RN, et al. Prophylactic antibiotic guidelines in modern interventional radiology practice[J]. Semin Intervent Radiol, 2010, 27: 327 337.
[12]鲁海涛, 王 珏, 张培蕾, 等. 介入手术抗菌药物应用的回顾性调查[J]. 介入放射学杂志, 2013, 22: 141 143.
[13] Meyer P, Reinzine D, Aymard A, et al. Septic complications in interventional radiology: evaluation of risk and preventive measures; Preliminary studies[J]. J InterventRadiol, 1988, 3: 73 75.
[14] Dravid VS, Gupta A, Zegel HG, et al. Investigation of antibiotic prophylaxis usage for vascular and nonvascular interventional procedures[J]. J Vasc Interv Radiol, 1998, 9: 401 406.
[15]曹 军, 刘洪强, 何 阳, 等. 血管介入治疗预防性应用抗菌药物对术后感染发生率影响的临床研究[J]. 临床和实验医学杂志, 2013, 12: 924 925, 927.
[16]王江云, 李彦豪, 汪能平, 等. 血管内介入治疗围手术期抗菌性药物应用的前瞻性研究[J]. 中华医院感染学杂志, 2010, 20: 2659 2661.
[17] Fiorani P, Speziale F, Calisti A, et al. Endovascular graft infection: preliminary results of an international enquiry[J]. J Endovasc Ther, 2003, 10: 919 927.

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备注/Memo

备注/Memo:
(收稿日期:2014-08-19)
(本文编辑:边 佶)
更新日期/Last Update: 2015-04-27