[1]王玉萍,沈世林,苏东君,等.对比剂肾病研究进展 [J].介入放射学杂志,2017,(06):572-575.
 WANG Yuping,SHEN Shilin,SU Dongjun,et al.Research progress in contrast- induced nephropathy[J].journal interventional radiology,2017,(06):572-575.
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对比剂肾病研究进展


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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年06期
页码:
572-575
栏目:
综述
出版日期:
2017-06-25

文章信息/Info

Title:
Research progress in contrast- induced nephropathy
作者:
王玉萍 沈世林 苏东君 何岳珍 陈辅环
Author(s):
WANG Yuping SHEN Shilin SU Dongjun HE Yuezhen CHEN Fuhuan
The First Hospital of Lanzhou University, Lanzhou, Gansu Province 730000, China
关键词:
【关键词】 对比剂 对比剂肾病 预防
文献标志码:
A
摘要:
【摘要】 随着对比剂在现代医学中广泛应用,对比剂肾病(CIN)也引起临床上更多关注。肾缺血和肾小管毒性被认为是CIN发病机制。相关检测指标除血清肌酐(SCr)外,中性粒细胞明胶酶相关载脂蛋白(NGAL)、胱抑素C(Cys C)、肾损害分子- 1(KIM- 1)、尿N- 乙酰- β- D氨基葡萄糖苷酶(NAG)和微小核糖核酸(miRNA)是最有前景的生物标志物。对比剂造影前必须评估患者自身危险因素(基础肾功能情况、糖尿病、贫血、高同型半胱氨酸等)和对比剂相关危险因素(对比剂渗透压、黏滞度、用量、应用频度等)。CIN治疗目前仍以水化疗法为主,其它方法包括他汀类、血管扩张剂、抗氧化剂、中医药等药物治疗,以及血液净化疗法。该文就CIN诊断、发病机制、危险因素和防治措施等研究进展作一简要综述。

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备注/Memo

备注/Memo:
(收稿日期:2016-10-22)
(本文编辑:边 佶)
更新日期/Last Update: 2017-06-13