[1]路军良,杨宁,赵士军,等.自制机械祛栓器械治疗急性大块肺动脉栓塞的实验研究[J].介入放射学杂志,2008,(04):262.
　LU Junliang,YANG Ning,ZHAO Shijun,et al.The primary experimental study of self－made percutaneous catheterized thrombectomy device for acute massive pulmonary embolism[J].journal interventional radiology,2008,(04):262.
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自制机械祛栓器械治疗急性大块肺动脉栓塞的实验研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年04期
页码:
262
栏目:
实验研究
出版日期:
2008-04-15

文章信息/Info

Title:
The primary experimental study of self－made percutaneous catheterized thrombectomy device for acute massive pulmonary embolism
作者:
路军良; 杨宁; 赵士军; 等
１００７００中国协和医科大学北京协和医院放射科（路军良、杨宁）；唐山丰润区人民医院（赵士军、马俊山）；河北冀州市人民医院（杨建平）
Author(s):
LU Jun－liang; YANG Ning; ZHAO Shi－jun; MA Jun－shan; YANG Jian－ping
Department of Radiology，Peking Union Medical University，Beijing１００７００，China
关键词:
动物模型; 肺动脉栓塞; 器械祛栓
分类号:
R５４３.５
文献标志码:
B
摘要:
目的检测自制机械祛栓器在动物体内应用的祛栓效能、可行性和安全性。方法杂种犬７只，采用经股静脉插管至一侧肺动脉主干后注入血栓制作急性大块肺动脉栓塞模型，模型制作成功半小时后开始进行祛栓，入路分别采取经右股静脉５只，左股静脉、右侧颈内静脉各１只。记录祛栓时间和抽出血液量；并行血管造影，肺动脉压测定；血气测定；动物在祛栓２h后处死。结果１只犬在祛栓过程中损伤肺动脉引起出血死亡，６只均顺利完成本实验。平均祛栓干预时间为２．４min，收集的血液平均为８４ml ；祛栓后中央肺动脉基本通畅；肺动脉压均可降至正常水平；血气也大部恢复正常水平；病理切片显示祛栓后被栓塞中央动脉腔通畅。结论实验初步证实本器械在急性大块肺栓塞的祛栓治疗中是可行的，基本上安全。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：２００７－１１－１２
更新日期/Last Update: 2008-04-15