[1]何闯,吴蔚,袁晶,等.CT引导下穿刺活检对ⅠA期非小细胞肺癌疾病无进展生存期和总生存期的影响[J].介入放射学杂志,2020,29(04):372-375.
　HE Chuang,WU Wei,YUAN Jing,et al. The influence of CT-guided needle biopsy on disease-free progressive survival and overall survival in patients with stage ⅠA non-small cell lung cancer[J].journal interventional radiology,2020,29(04):372-375.
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CT引导下穿刺活检对ⅠA期非小细胞肺癌疾病无进展生存期和总生存期的影响()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年04
页码:
372-375
栏目:
非血管介入
出版日期:
2020-05-08

文章信息/Info

Title:
 The influence of CT-guided needle biopsy on disease-free progressive survival and overall survival in patients with stage ⅠA non-small cell lung cancer
作者:
何闯; 吴蔚; 袁晶; 陈玉潇; 杨丽; 李良山; 李廷源; 黄学全
Author(s):
HE Chuang;  WU Wei;  YUAN Jing;  CHEN Yuxiao;  YANG Li;  LI Liangshan;  LI Tingyuan;  HUANG Xuequan.
Department of Minimally-Invasive Intervention, First Affiliated Hospital of Army Medical University (Third Military Medical University), Chongqing 400038, China
关键词:
【关键词】　非小细胞肺癌; ⅠA期; 活检
文献标志码:
A
摘要:
【摘要】　目的?探讨ⅠA期非小细胞肺癌（NSCLC）患者根治术术前活检是否影响患者的疾病无进展生存期（PFS）和总生存期（OS）。方法?回顾性收集2007—2014年行根治术的ⅠA期NSCLC患者225例，根据是否行CT引导下穿刺活检，依临床基本特征进行1∶1倾向性匹配分析（PSM），活检组和非活检组分别有47例纳入研究。采用Kaplan-Meier生存曲线和Cox回归分析进行生存分析。
结果?经PSM匹配后两组基本临床资料无显著差异。匹配后中位随访时间58.5个月，活检组和非活检组的PFS分别为（64.8±31.4）和（61.2±34.4）个月，两组PFS差异无统计学意义（χ2=0.020，P=0.888），OS分别为（67.9±30.2）、（65.3±31.3）个月，差异无统计学意义（χ2=0.003，P=0.955）。单因素和多因素分析显示根治术术前行CT引导下经皮穿刺活检不是患者PFS和OS的影响因素。结论?ⅠA期NSCLC术前行CT引导下经皮穿刺活检不影响患者的PFS和OS。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：2019-06-11）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2020-05-06