[1]史诗洁,詹迎江,童林军,等.西艾克介入性治疗肝癌、肺癌的临床研究[J].介入放射学杂志,1998,(01):29-31.
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西艾克介入性治疗肝癌、肺癌的临床研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
1998年01期
页码:
29-31
栏目:
试验研究
出版日期:
2000-01-01

文章信息/Info

作者:
史诗洁;詹迎江;童林军;涂建英;吉美玲;程永德;
解放军第八五医院
关键词:
肝癌;  肺癌;  西艾克;  介入治疗
摘要:
目的:观察西艾克介入性治疗肝癌、肺癌的疗效及毒副反应。材料与方法:采用杭州民生制药厂生产的西艾克,分别与5-Fu、MMC、卡铂、Vp16组成不同的化疗方案,对30例不能手术的中晚期肝癌和肺癌进行动脉灌注化疗,其中原发性肝癌13例,转移性肝癌7例,原发性肺癌10例。全部病例均采用Seldinger 法将导管超选择插至肝总动脉和支气管动脉后,缓慢注入稀释的联合化疗药物。治疗前后均复查血象、肝功、肾功、CT 等以评价疗效及毒副反应。结果:以 CR+PR 为有效,原发性肝癌有效率为61.5%。转移性肝癌有效率为42.9%,原发性肺癌有效率为70%.总有效率60%。该药的骨髓抑制的毒副作用较大,70%病人有恶心、呕吐等消化道反应,脱发、指端麻木等毒副作用轻。结论:临床研究表明西艾克对肺癌有良好的疗效,但对肝癌的疗效一般,和其它的抗肝癌药物相比无显著差异。

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更新日期/Last Update: 1900-01-01