[1]刘平,曾伟华,李后炳,等.肝癌介入治疗药动学及其临床意义探讨[J].介入放射学杂志,1995,(02):67-69.
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肝癌介入治疗药动学及其临床意义探讨()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
1995年02期
页码:
67-69
栏目:
临床研究
出版日期:
2000-01-01

文章信息/Info

作者:
刘平;曾伟华;李后炳;潘云艳;杜运生;
湖南湘潭市中心医院
关键词:
肝癌 动脉 栓塞 阿霉素 微囊 药动学
摘要:
本研究通过测定血清阿霉素浓度,分析了原发性肝癌阿霉素肝动脉灌注(A 组)、阿霉素碘油乳化后栓塞(B 组)及阿霉素微囊栓塞化疗(C 组)后药动学变化及其临床意义。A 组药动学变化与静脉给药相似,但峰值浓度高。B 组峰浓度低,半衰期延长,显示缓释和降低血浓度的作用。C 组峰浓度不明显,表现为长时、稳定的释放,血浓度低,具有保持局部长时间高浓度作用。结果揭示了肝癌介入治疗不同给药方法疗效差异的药动学依据。

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更新日期/Last Update: 1900-01-01