[1]朱悦琦,李明华,方淳,等.应用Willis覆膜支架治疗脑池段动脉瘤的临床对照研究和长期随访结果[J].介入放射学杂志,2010,(04):275.
　ZHU Yueqi,LI Minghua,FANG Chun,et al.Application of Willis covered stent in the treatment of aneurysms located in the cisternal segment of the internal carotid artery：a pilot comparative study with long－term follow－up results[J].journal interventional radiology,2010,(04):275.
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应用Willis覆膜支架治疗脑池段动脉瘤的临床对照研究和长期随访结果()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年04期
页码:
275
栏目:
神经介入
出版日期:
2010-04-15

文章信息/Info

Title:
Application of Willis covered stent in the treatment of aneurysms located in the cisternal segment of the internal carotid artery：a pilot comparative study with long－term follow－up results
作者:
朱悦琦; 李明华; 方淳; 等
２００２３３上海交通大学医学院附属第六人民医院放射科（朱悦琦、李明华、方淳、王武、张培蕾、谭华桥、王建波）；上海同济大学医学院附属第十人民医院放射科（程英升）
Author(s):
ZHU Yue－qi ; LI Ming－hua; FANG Chun; WANG Wu ; ZHANG Pei－lei; CHENG Ying－sheng; TAN Hua－qiao; WANG Jian－bo．
the Affiliated Sixth People’s Hospital，School of Medicine，Shanghai Jiaotong University，Shanghai２００２３３，China
关键词:
血管内治疗; 覆膜支架; 动脉瘤; 脑池段
分类号:
R７４３.４
摘要:
目的复杂性颈内动脉脑池段动脉瘤（ICA－CSA）治疗难度很高。本研究通过与弹簧圈填塞治疗疗效比较，探讨Willis覆膜支架治疗ICA－CSA的可行性。方法１９枚和１７枚ICA－CSA分别使用Willis覆膜支架植入（A组）和弹簧圈（B组）填塞治疗。即刻和随访血管造影评价动脉瘤复发，内漏和载瘤动脉狭窄情况。Kaplan－Meier生存分析曲线比较两组治疗动脉瘤的无复发率和载瘤动脉无再狭窄率。结果A组中，１３枚ICA－CSA植入支架，即刻造影完全闭塞，有５枚ICA－CSA存在少量内漏；B组中，７枚ICA－CSA弹簧圈填塞即刻达到完全和次完全闭塞，８枚达到大部填塞，２枚部分填塞。在两组中各发生１例急性血栓形成，１例弹簧圈填塞后发生再出血。A组随访造影显示１６枚ICA－CSA完全闭塞，２支载瘤动脉有轻度狭窄。Kaplan－Meier曲线分析表明术后１８个月两组病例中分别有９３．３％和５０％动脉瘤治疗后无复发，分别有８７．５％和１００％载瘤动脉无狭窄。临床症状随访研究表明A组和B组病例中神经症状完全恢复分别为９例和９例，明显改善分别为３例和５例，无改变分别为２例和２例，恶化进展分别为１例和０例。结论应用Willis覆膜支架植入治疗复杂性ICA－CSA是一种可行的血管内治疗方法，但是对于载瘤动脉极其弯曲和重要侧支覆盖风险的情况下，覆膜支架技术不能作为第一选择。

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备注/Memo

备注/Memo:
收稿日期：２０１０－０１－２６
基金项目：本研究受国家自然科学基金（编号：３０５７０５４０）；上海市医学重点项目（编号：０５Ⅲ０２３）；博士创新课题资金（编号：BXJ０９３３）资助
更新日期/Last Update: 2010-04-15