[1]丁婷婷,畅智慧,刘兆玉.支架内再狭窄非编码核糖核酸靶向治疗研究进展[J].介入放射学杂志,2022,31(02):210-213.
 DING Tingting,CHANG Zhihui,LIU Zhaoyu..Advances in non-coding ribonucleic acid-targeted therapy for in-stent restenosis[J].journal interventional radiology,2022,31(02):210-213.
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支架内再狭窄非编码核糖核酸靶向治疗研究进展()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年02
页码:
210-213
栏目:
综述
出版日期:
2022-02-25

文章信息/Info

Title:
Advances in non-coding ribonucleic acid-targeted therapy for in-stent restenosis
作者:
丁婷婷 畅智慧 刘兆玉
Author(s):
DING Tingting CHANG Zhihui LIU Zhaoyu.
Department of Radiology, Affiliated Shengjing Hospital of China Medical University, Shenyang, Liaoning Province 110004, China
关键词:
【关键词】 非编码核糖核酸 下肢动脉硬化闭塞症 支架内再狭窄 血管平滑肌细胞
文献标志码:
A
摘要:
【摘要】 血管内支架植入术作为一种微创、安全有效的方法,近年来广泛应用于下肢动脉硬化闭塞症(ASO)治疗,但支架内再狭窄(ISR)(血管直径缩小至参考血管直径50%以上)发生率仍然很高。因此,如何治疗ISR成为临床主要问题。非编码核糖核酸(ncRNA)是一类不编码蛋白质核糖核酸(RNA)分子,如微RNA(microRNA,miRNA)、环状RNA(circRNA)、长链非编码RNA(lncRNA)的统称,可调节ncRNA中血管平滑肌细胞表型转化,如增殖、迁移、凋亡、新生内膜增殖等。该文举例说明了ncRNA作为ISR治疗可能的生物标志物或潜在治疗靶标,并阐述了相关新思想和新发现。

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备注/Memo

备注/Memo:
(收稿日期:2020- 10- 01)
(本文编辑:边 佶)

更新日期/Last Update: 2022-02-21