[1]李成州,贾宁阳,姜庆军,等.522例肺部病变CT引导经皮切割针活检总结[J].介入放射学杂志,2008,(10):716.
 LI Chengzhou,JIA Ningyang,JIANG Qingjun,et al.Clinical evaluation of percutaneous transthoracic needle core-biopsy under CT guidance(with522cases reports)[J].journal interventional radiology,2008,(10):716.
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522例肺部病变CT引导经皮切割针活检总结()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年10期
页码:
716
栏目:
非血管介入
出版日期:
2008-10-15

文章信息/Info

Title:
Clinical evaluation of percutaneous transthoracic needle core-biopsy under CT guidance(with522cases reports)
作者:
李成州贾宁阳姜庆军
200233上海交通大学附属第六人民医院放射科(李成州、吴春根、丁月根);第二军医大学长征医院影像科(贾宁阳、张电波、刘士远、肖湘生);解放军济南军区总医院放射科(姜庆军)
Author(s):
LI Cheng-zhouJIA Ning-yangJIANG Qing-junWU Chun-genZHANG Dian-boDIN Yue-genLIU Shi-yuanXIAO Xiang-sheng.
Department of Radiology,Sixth Hospital,Shanghai Jiaotong University,Shanghai200233,China
关键词:
断层摄影术X线计算机放射学介入性活组织检查肺部疾病
分类号:
R437.2
文献标志码:
A
摘要:
目的总结CT引导经皮切割针穿刺活检术对肺部病变诊断的准确性、灵敏度、特异度和并发症。方法收集1992年以来,取材成功并有完整资料的522例CT引导经皮肺部切割针穿刺活检病例作回顾性分析。其中肺部结节或肿块性病变467例,其他病变55例。统计该法诊断灵敏度、特异度和并发症,并分析其影响因素。结果476例获得组织标本并有病理学结果,取材成功率为91.2%(476/522)。301例病理确诊为恶性肿瘤,包括腺癌107例,鳞状细胞癌84例,不能分型恶性肿瘤59例,小细胞未分化癌16例,肺转移瘤22例,低度恶性肿瘤3例,肺肉瘤3例,细支气管肺泡细胞癌2例,5例病理报告为“癌变可疑”,后证实为支气管肺癌。17例穿刺病理为“癌变可疑”,后证实为良性病变。穿刺未发现癌细胞者204例,其中明确诊断为良性病变102例(结核41例,非特异性肺炎21例,慢性炎症18例,支气管扩张7例,炎性假瘤6例,曲霉感染5例,隐球菌性肺炎3例,良性纤维组织细胞瘤1例)。非特异性病理结果的良性病变73例。另29例穿刺未发现肿瘤组织,而后证实为恶性肿瘤,系假阴性。阳性预测值为94.7%〔301/(301+17)〕,灵敏度为91.2%〔301/(301+29)〕,特异度为91.1%〔175/(175+17)〕,假阴性率为14.2%(29/204)。54例发生气胸,占10.3%(54/522),仅1.5%的病例(8/522)行抽气或置管闭式引流处理。肺出血42例,咯血36例,均未经特殊处理而自愈。结论CT引导经皮切割针肺部病灶活检具有较高的诊断灵敏度和特异度,有助于提高良性病变的诊断准确性,同时并不显著增加气胸和出血等并发症的发生率。

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备注/Memo

备注/Memo:
收稿日期:2008-01-22
更新日期/Last Update: 2008-10-15