[1]王 猛,崔 瑶,杜可朴,等.CT引导经胸骨路径125I粒子植入治疗纵隔肿瘤的临床价值 [J].介入放射学杂志,2021,30(06):604-607.
 WANG Meng,CUI Yao,DU Kepu,et al.The clinical value of CT-guided 125I seed implantation via trans-sternum approach in treating mediastinal tumors[J].journal interventional radiology,2021,30(06):604-607.
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CT引导经胸骨路径125I粒子植入治疗纵隔肿瘤的临床价值
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年06
页码:
604-607
栏目:
临床研究
出版日期:
2021-06-26

文章信息/Info

Title:
The clinical value of CT-guided 125I seed implantation via trans-sternum approach in treating mediastinal tumors
作者:
王 猛 崔 瑶 杜可朴 李 帅 刘婷婷 陈艳林 李亚丹 高 飞 周志刚
Author(s):
WANG Meng CUI Yao DU Kepu LI Shuai LIU Tingting CHEN Yanlin LI Yadan GAO Fei ZHOU Zhigang.
Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, China
关键词:
【关键词】 CT引导 经胸骨路径 125I粒子 纵隔肿瘤
文献标志码:
A
摘要:
【摘要】 目的 探讨经胸骨路径在CT引导125I粒子植入治疗位于前、中纵隔肿瘤的临床应用。方法 收集2017年9月至2019年9月接受CT引导经胸骨路径125I粒子植入治疗的20例前、中纵隔肿瘤患者临床资料。记录术后即刻剂量学参数,观察术后粒子分布满意率、并发症发生率及局部疗效,随访术后半年、1年的生存率。结果 术后即刻剂量验证剂量学参数如下:90%肿瘤靶区接受剂量(D90)(134.30±14.53) Gy;肿瘤靶区接受90%、100%、150%和200%处方剂量的体积百分比(V90、V100、V150和V200)分别为(97.15±2.09)%、(93.04±1.75)%、(66.86±7.53)%、(42.95±9.11)%;适形指数(conformity index,CI)、靶区外体积指数(EI)、均匀性指数(homogeneity index,HI)分别为0.65±0.06、(40.79±13.72)%、(27.90±7.53)%。粒子分布满意率90%。术后即刻1例患者出现气胸、1例患者出现咯血。平均随访(12.0±4.8)个月(4~24个月),术后2个月、半年、1年局部控制率分别为65.0%、64.7和53.8%。半年、1年生存率89.5%和81.3%。随访期间有4例患者死亡、3例患者出现局部进展,无放射相关并发症发生。结论 经胸骨路径是CT引导125I粒子植入治疗前、中纵隔肿瘤的安全路径,术后粒子分布满意率高。

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备注/Memo

备注/Memo:
(收稿日期:2020- 04- 11)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2021-06-25