[1]鲁小敏,顾裕平,吴桂鹏,等.应用低容量苯酚腹腔神经丛毁损治疗上腹部癌痛[J].介入放射学杂志,2021,30(11):1166-1169.
 LU Xiaomin,GU Yuping,WU Guipeng,et al.CT-guided celiac nerve plexus block by using low-volume phenol injection for the treatment of upper abdominal cancerous pain[J].journal interventional radiology,2021,30(11):1166-1169.
点击复制

应用低容量苯酚腹腔神经丛毁损治疗上腹部癌痛()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年11
页码:
1166-1169
栏目:
临床研究
出版日期:
2021-11-25

文章信息/Info

Title:
CT-guided celiac nerve plexus block by using low-volume phenol injection for the treatment of upper abdominal cancerous pain
作者:
鲁小敏 顾裕平 吴桂鹏 史传岗
Author(s):
LU Xiaomin GU Yuping WU Guipeng SHI Chuangang.
Affiliated Hai’an Hospital of Nantong University, Nantong, Jiangsu Province 226600, China
关键词:
【关键词】 CT引导苯酚癌性疼痛腹腔神经丛
文献标志码:
A
摘要:
【摘要】 目的 评估单针低容量苯酚毁损腹腔神经丛治疗上腹部癌性疼痛,为晚期上腹部癌痛患者的治疗提供参考。方法 回顾性分析2017年12月到2019年12月147例晚期癌痛患者行CT引导低容量苯酚腹腔神经丛毁损的临床资料。对在CT引导下低容量苯酚行腹腔神经丛毁损前后的疼痛评分、阿片类药物的每日摄入量、肿瘤患者生活质量指数的6个月随访期间的数据进行分析,同时收集手术时间以及与手术相关的并发症发生情况。结果 随访期间患者的疼痛评分、每日阿片类药物摄入量和生活质量较术前均得到显著改善(P<0.05)。由于疾病进展,在第4至第6个月疼痛评分有所恢复。9例患者术中发现血管摄取对比剂征象,术后27.2%患者出现了低血压,14.9%患者出现了短暂性的腹泻。所有患者均无腹部灼痛和醉酒征象出现。结论 CT引导单针低剂量苯酚用于腹腔神经丛毁损是一种有效、安全且耗时较少缓解上腹部癌痛的方法,可提供长达6个月的疼痛缓解。

参考文献/References:

[1] Bornstein E, Husk G, Lenchner E, et al. Implementation of a standardized post- cesarean delivery order set with multimodal combination analgesia reduces inpatient opioid usage[J]. J Clin Med, 2020, 10: 7.
[2] Bhutiani N, Cheadle GA, Bahr MH, et al. Comparative efficacy of bilateral thoracoscopic splanchnicectomy for intractable pain secondary to pancreatic cancer vs chronic pancreatitis[J]. J Am Coll Surg, 2017, 224: 566- 571.
[3] Tewari S, Agarwal A, Dhiraaj S, et al. Comparative evaluation of retrocrural versus transaortic neurolytic celiac plexus block for pain relief in patients with upper abdominal malignancy: a retros-pective observational study[J]. Indian J Palliat Care, 2016, 22: 301- 306.
[4] Amr SA, Reyad RM, Othman AH, et al. Comparison between radiofrequency ablation and chemical neurolysis of thoracic splanchnic nerves for the management of abdominal cancer pain, randomized trial[J]. Eur J Pain, 2018, 22: 1782- 1790.
[5] 吴泽涛,李焕祥,吕峰泉,等. 可控弯针经皮穿刺腹腔神经丛毁损术治疗上腹部癌痛18例[J]. 介入放射学杂志, 2014, 23:916- 919.
[6] Novy DM, Engle MP, Lai EA, et al. Effectiveness of splanchnic nerve neurolysis for targeting location of cancer pain: using the pain drawing as an outcome variable[J]. Pain Physician, 2016, 19: 397- 403.
[7] Wang L, Lu M, Wu X, et al. Contrast- enhanced ultrasound- guided celiac plexus neurolysis in patients with upper abdominal cancer pain: initial experience[J]. Eur Radiol, 2020, 30: 4514- 4523.
[8] Comlek S. Pain control with splanchnic neurolysis in pancreatic cancer patients unresponsive to celiac plexus neurolysis[J]. J Pain Res, 2020, 13: 2023- 2031.
[9] Yokoyama A, Kamada Y, Imazeki H, et al. Effects of ADH1B and ALDH2 genetic polymorphisms on alcohol elimination rates and salivary acetaldehyde levels in intoxicated Japanese alcoholic men[J]. Alcohol Clin Exp Res, 2016, 40: 1241- 1250.
[10] Yokoyama A, Mizukami T, Yokoyama T. Genetic polymorphisms of alcohol dehydrogense- 1B and aldehyde dehydrogenase- 2, alcohol flushing, mean corpuscular volume, and aerodigestive tract neoplasia in Japanese drinkers[J]. Adv Exp Med Biol, 2015, 815: 265- 279.
[11] Lee J, Kim BH, Yu KS, et al. A first- in- human, double- blind, placebo- controlled, randomized, dose escalation study of DWP- 05195, a novel TRPV1 antagonist, in healthy volunteers[J]. Drug Des Devel Ther, 2017, 11: 1301- 1313.
[12] 陈 炜,费 勇,姚 明,等. CT引导下无水乙醇腹腔神经丛阻滞术治疗顽固性上腹部癌痛的量效关系[J]. 中华麻醉学杂志, 2020, 40:320- 322.
[13] Bang JY, Sutton B, Hawes RH,et al. EUS- guided celiac ganglion radiofrequency ablation versus celiac plexus neurolysis for palliation of pain in pancreatic cancer: a randomized controlled trial(with videos)[J]. Gastrointest Endosc, 2019, 89: 58- 66.
[14] Ishiwatari H, Hayashi T, Yoshida M, et al. Phenol- based endoscopic ultrasound- guided celiac plexus neurolysis for East Asian alcohol- intolerant upper gastrointestinal cancer patients: a pilot study[J]. World J Gastroenterol, 2014, 20: 10512- 10517.

相似文献/References:

[1]张 勇,周玉梅,陈淑君,等.明胶海绵颗粒联合凝血酶预防CT引导下卵巢癌穿刺活检术后针道出血[J].介入放射学杂志,2016,(05):412.
 ZHANG Yong,ZHOU Yu- mei,CHEN Shu- jun,et al.Combination use of gelatin sponge particles and thrombin solution injection for the prevention of needle tract bleeding after CT- guided biopsy of ovarian cancer[J].journal interventional radiology,2016,(11):412.
[2]章 阳,肖天林.CT引导下中心静脉导管置管引流心包积液的临床分析[J].介入放射学杂志,2016,(09):789.
 ZHANG Yang,XIAO Tian- lin.CT- guided central venous catheter drainage for the treatment of pericardial effusion: a clinical analysis[J].journal interventional radiology,2016,(11):789.
[3]杨茂江,琼 仙,徐书琴,等.穿刺路径对CT引导下心包置管引流的价值[J].介入放射学杂志,2017,(02):173.
 YANG Maojiang,QIONG Xian,XU Shuqin,et al.The clinical value of selection of the puncture path in performing CT-guided pericardial drainage [J].journal interventional radiology,2017,(11):173.
[4]申玉鑫,周志刚,王 猛,等.CT引导下氩氦刀冷冻消融治疗平滑肌肉瘤临床疗效观察 [J].介入放射学杂志,2018,27(03):228.
 SHEN Yuxin,ZHOU Zhigang,WANG Meng,et al.CT- guided argon- helium cryoablation for the treatment of leiomyosarcoma: observation of clinical efficacy[J].journal interventional radiology,2018,27(11):228.
[5]司宝霞,谭 华.CT引导下臭氧靶点椎间盘注射治疗腰1/2椎间盘突出症1例[J].介入放射学杂志,2019,28(07):690.
 SI Baoxia,TAN Hua..CT- guided injection of ozone in target intervertebral disc for the treatment of lumbar 1-2 irtervertebral disc protrusion: report of one case[J].journal interventional radiology,2019,28(11):690.
[6]陈小峰,曹 晔,浦建枫,等.CT引导下水针刀靶向微创松解技术在腰椎间盘突出症治疗中的应用研究 [J].介入放射学杂志,2019,28(08):754.
 CHEN Xiaofeng,CAO Ye,PU Jianfeng,et al.Application of CT- guided targeted minimally- invasive release technique with water needle knife in treating lumbar disc herniation[J].journal interventional radiology,2019,28(11):754.
[7]王 猛,崔 瑶,杜可朴,等.CT引导经胸骨路径125I粒子植入治疗纵隔肿瘤的临床价值 [J].介入放射学杂志,2021,30(06):604.
 WANG Meng,CUI Yao,DU Kepu,et al.The clinical value of CT-guided 125I seed implantation via trans-sternum approach in treating mediastinal tumors[J].journal interventional radiology,2021,30(11):604.
[8]杨崇双,黄学全,何 闯,等.CT引导下经皮锁骨上穿刺胸腔胃造瘘1例[J].介入放射学杂志,2023,32(02):166.
 YANG Chongshuang,HUANG Xuequan,HE Chuang,et al.CT-guided percutaneous supraclavicular puncture thoracic gastrostomy: report of one case[J].journal interventional radiology,2023,32(11):166.
[9]李东源,李良山,刘 丽,等.CT引导下肠道占位病变穿刺活检的临床应用[J].介入放射学杂志,2023,32(08):804.
 LI Dongyuan,LI Liangshan,LIU Li,et al.Clinical application of CT-guided puncture biopsy in diagnosing intestinal space-occupying lesions[J].journal interventional radiology,2023,32(11):804.
[10]吉冬梅,卢 丹.CT引导下高电压长时程脉冲射频与神经阻滞治疗阴部神经痛的疗效分析[J].介入放射学杂志,2023,32(12):1216.
 JI Dongmei,LU Dan..CT- guided high-voltage long-duration pulsed radiofrequency versus nerve block in the treatment of pudendal neuralgia: an analysis of efficacy[J].journal interventional radiology,2023,32(11):1216.

备注/Memo

备注/Memo:
(收稿日期:2020- 10- 01)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2021-11-22