[1]钱 亭,陈茂振,高 峰,等. 两种方法建立兔VX2肝癌模型的比较及影像学评估[J].介入放射学杂志,2014,(01):58-61.
　QIAN Ting,CHEN Mao? zhen,GAO Feng,et al. Comparison of two methods used in establishing VX?蛳 2 liver tumor model in rabbits and their imaging evaluation[J].journal interventional radiology,2014,(01):58-61.
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 两种方法建立兔VX2肝癌模型的比较及影像学评估 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年01期
页码:
58-61
栏目:
实验研究
出版日期:
2014-01-20

文章信息/Info

Title:
 Comparison of two methods used in establishing VX?蛳 2 liver tumor model in rabbits and their imaging evaluation
作者:
钱 亭;  陈茂振;  高 峰;  尹化斌 
Author(s):
 QIAN Ting;  CHEN Mao?蛳 zhen;  GAO Feng;  YIN Hua?蛳 bin.
 Department of Radiology， Shanghai Municipal Fifth People’s Hospital， Shanghai 200240， China
关键词:
 ; 【关键词】 肝肿瘤;  VX2肿瘤;  影像学评估;  动物模型
文献标志码:
A
摘要:
 【摘要】 目的 比较两种方法建立兔VX2肝癌模型的成瘤情况及CT、DSA表现。方法 采用新西兰白兔40只，随机分成A、B两组，每组20只。A组采用开腹包埋植入VX2瘤块，B组采用CT引导下穿刺种植VX2瘤块，术后2周行CT及DSA检查。结果 A组成瘤率为50%（10/20），B组为85%（17/20），组间差异有统计学意义（P < 0.05）。与A组相比，B组操作简单、成瘤率高。两组CT及DSA造影表现一致。结论 两种方法建立的兔VX2肝癌模型的CT及DSA影像学表现无差别，CT引导下经皮穿刺种植法的应用优于开腹种植。

参考文献/References:

 ［1］ Lee KH， Liapi E， Buijs M， et al. Percutaneous US?蛳 guided implantation of VX?蛳 2 carcinoma into rabbit liver： a comparison with open surgical method［J］. J Surg Res， 2009， 155： 94 ?蛳 99.
［2］ 江雄鹰， 罗荣光， 黄金华， 等． 兔VX2肝癌模型建立与经兔股动脉微导管超选择性肝左动脉插管技术的探讨［J］． 介入放射学杂志， 2011， 20： 214 ?蛳 217．
［3］ Watanabe D， Ueo H， Inoue H， et al. Antitumor effects of intraarterial infusion of tumor necrosis factor/lipiodol emulsion on hepatic tumor in rabbits［J］. Oncology， 1995， 52： 76 ?蛳 81.
［4］ Swistel AJ， Bading JR， Raaf JH. Intraarterial versus intravenous adriamycin in the rabbit VX ?蛳 2 tumor system［J］. Cancer， 1984， 53： 1397 ?蛳 1404.
［5］ 史东宏， 曹建民， 许 健， 等． CT引导下兔VX2肝癌模型的制作及综合评估［J］． 介入放射学杂志， 2008， 17： 725 ?蛳 728． 

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 （收稿日期：２０１3-０5-15）
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