[1]周承凯,梁惠民,李欣,等.实验兔VX2肝肿瘤模型制作及动脉插管技术探讨[J].介入放射学杂志,2006,(02):101-104.
 ZHOU Cheng-kai,LIANG Hui-ming,LI Xin,et al.Establishment of rabbit model bearing VX2 liver tumor experimentation and discussion of the selective hepatic arterial catheterization.[J].journal interventional radiology,2006,(02):101-104.
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实验兔VX2肝肿瘤模型制作及动脉插管技术探讨()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2006年02期
页码:
101-104
栏目:
实验研究
出版日期:
2006-02-01

文章信息/Info

Title:
Establishment of rabbit model bearing VX2 liver tumor experimentation and discussion of the selective hepatic arterial catheterization.
作者:
周承凯 梁惠民 李欣 柳曦
430022,武汉,华中科技大学同济医学院附属协和医院放射科
Author(s):
ZHOU Cheng-kaiLIANG Hui-mingLI Xinet al
关键词:
肝癌 动物模型 介入治疗
分类号:
R73.36
摘要:
目的介绍应用VX2细胞株制作兔移植性肝癌模型,并探讨插管技术的应用.方法实验对象为新西兰大白兔(n=80),VX2瘤块组织接种于肝脏,接种后2~3周实验组(n=51)行剖腹直视下肝动脉直接楔入插管,并作DSA造影.对照组1和2(各10只)分别采取经股动脉-肝动脉插管和开腹经胃十二指肠动脉逆行插管方法对比研究.结果实验组插管成功率为98%(50/51),其中88%(45/51)完成超选择栓塞;对照组1和2的插管成功率分别为30%和40%,只有0/10和4/10完成超选择栓塞.结论移植性兔VX2肝癌是介入治疗实验研究较为理想的动物模型,综合影像评价有利于实验动物的筛选。采用肝动脉细针直接穿刺楔入法插管成功率高,可完成超选择栓塞,是值得推广的实验方法。

参考文献/References:

[1] Burgener H Peripheral hepatic artery embolization in rabbits with VX2 carcinoma of the liver[J] Cancer ,1980,46:56
[2] Miao Y.Ni Y.Bosmans H Radiofrequency ablation for eradication of renal tumor in a rabbit model by using a cooled-tip electrode technique[J] .Ann Surg Oncol,2001,8:651-657

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备注/Memo

备注/Memo:
(收稿日期:2004-11-09)
更新日期/Last Update: 2010-11-19