[1]李振武,张伟,孙立军.磁共振扩散加权成像在肝癌化疗栓塞术后随访中的价值[J].介入放射学杂志,2010,(08):610.
　LI Zhenwu,ZHANG Wei,SUN Lijun,et al.The clinical value of MR diffusion－weighted imaging in the follow－up observation of hepatocellular carcinoma after transcatheter arterial chemoembolization[J].journal interventional radiology,2010,(08):610.
点击复制

磁共振扩散加权成像在肝癌化疗栓塞术后随访中的价值()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年08期
页码:
610
栏目:
肿瘤介入
出版日期:
2010-08-15

文章信息/Info

Title:
The clinical value of MR diffusion－weighted imaging in the follow－up observation of hepatocellular carcinoma after transcatheter arterial chemoembolization
作者:
李振武; 张伟; 孙立军
７１００３２西安第四军医大学西京医院放射科
Author(s):
LI Zhen－wu; ZHANG Wei; SUN Li－jun; QI Shun．
the Affiliated Xijing Hospital，the Forth Military Medical University，Xi ’an７１００３２，China
关键词:
扩散加权成像; 肝癌; 化疗栓塞术
分类号:
R７３５.７
文献标志码:
A
摘要:
目的探讨MR扩散加权成像（DWI ）在肝癌化疗栓塞术后随访中的应用价值。方法对l６例行TACE术的肝癌患者行MR DWI 并与DSA或CT造影检查相对照；分别测量病灶的表观扩散系数（apparent diffusion coefficient ，ADC）值并对比肝内转移灶与原发灶的ADC值。结果碘油沉积良好者１１处，其余７处沉积欠佳；正常肝实质的ADC值术前与术后无明显变化（t＝０．５４，P＞０．０５）。沉积欠佳组ADC值明显低于沉积良好组（t＝４．８１，P＜０．０１），沉积良好组术前ADC值与术后相比有所升高（t＝６．８１，P＜０．０１），而沉积欠佳组未见明显变化（４处稍降低）。另外，DWI 发现１２处肝内转移灶，转移灶与原发灶之间ADC值对比，两者差距有统计学意义（t＝４．６１，P＜０．０１）。结论DWI 可以灵敏地发现转移性病灶，也可以用来评价TACE的栓塞效果。

参考文献/References:

［１］李彦豪．实用介入诊疗技术图解［M］．北京：科学出版社，２００２．
［２］袁正，肖湘生，刘士远，等．磁共振扩散加权成像在肝癌TACE术后随访中的定性和定量应用［J］．介入放射学杂志，２００７，１６：８２２－８２６．
［３］郑晓林，徐辉雄，吕明德，等．磁共振弥散加权成像检测肝内小病灶的临床应用［J］．中国医学影像技术，２００４，２：１５１０－１５１２．
［４］肖运平，肖恩华，罗建光，等．MR扩散成像在肝细胞癌经导管动脉化疗栓塞术后疗效评价中的价值［J］．中国医学影像技术，２００８，２４：２７０－２７３．
［５］Deng J，Rhee TK，Sato KT，et al．In Vivo Diffusion－weighted Imaging of Liver Tumor Necrosis in the VX２Rabbit Model at１．５Tesla［J］．Invest Radiol，２００６，４１：４１０－４１４．
［６］Valonen PK，Lehtimaki KK，Vaisanen TH，et al．Water diffusion in a rat glioma during ganciclovirt hymidine kinase gene therapy－induced programmed cell death in vivo：correlation with cell density［J］．J Magn Reson Imaging，２００４，１９：３８９－３９６．
［７］尚全良，肖恩华，贺忠，等．肝癌经导管动脉灌注化疗栓塞术疗效的MR扩散加权成像动态研究［J］．中华放射学杂志，２００６，４０：２３５－２４０．

相似文献/References:

[1]曹海利,孟巍,白彬.肝癌基因治疗研究新进展[J].介入放射学杂志,2008,(05):375.
　CAO Haili,MENG Wei,BAI Bin.New progress in research of gene therapy for hepatocellular carcinoma[J].journal interventional radiology,2008,(08):375.
[2]陆骊工,胡宝山,李勇,等.中晚期原发性肝癌合并症的介入治疗研究[J].介入放射学杂志,2008,(07):514.
　LU Ligong,HU Baoshan,LI Yong,et al.Study of interventional therapy for complications in advanced primary hepatocellular carcinoma[J].journal interventional radiology,2008,(08):514.
[3]杨伟洪,刘鹏程,梁珊瑚,等.多层螺旋CT血管造影在判断肝癌寄生供血中的价值[J].介入放射学杂志,2008,(09):654.
　YANG Weihong,LIU Pengchen g,LIANG Shanhu,et al.Evaluation of MSCTA for parasitic blood supply in hepatic carcinoma[J].journal interventional radiology,2008,(08):654.
[4]张茵,周兵,许秀芳,等.肝动脉化疗栓塞治疗原发性肝癌存活２０年一例[J].介入放射学杂志,2008,(09):684.
　ZHANG Yin,ZHOU Bing,XU Xiufang,et al.Survival more than２０years after transarterial chemical embolization for hepatocellular carcinoma：A case report[J].journal interventional radiology,2008,(08):684.
[5]官泳松,贺庆.肝癌介入治疗中应用p５３的几个要点[J].介入放射学杂志,2008,(11):761.
　GUAN Yongsong,HE Qing.Essentials in clinical application of p５３for tumors intervention－example of liver cancer[J].journal interventional radiology,2008,(08):761.
[6]肖运平,肖恩华.介入治疗在防治肝癌术后复发中的作用及进展[J].介入放射学杂志,2008,(11):831.
　XIAO Yunping,XIAO Enhua.The role and progress of interventional therapy in the prevention and treatment of postoperative hepatocellular carcinoma recurrence[J].journal interventional radiology,2008,(08):831.
[7]史震山,陈自谦,杨熙章,等.原发性大肝癌患者TACE后S－腺苷蛋氨酸的护肝作用[J].介入放射学杂志,2008,(11):790.
　SHI Zhenshan,CHEN Ziqian,YANG Xizhang,et al.The clinical study on the liver－protection of S－adenosy－methionine in large hepatocellular carcinoma patients after TACE[J].journal interventional radiology,2008,(08):790.
[8]王耀普,杨康健,赵思源,等.兔肝癌模型的改良接种及其DSA影像分析[J].介入放射学杂志,2010,(03):214.
　WANG Yaopu,YANG Kangjian,ZHAO Siyuan,et al.The modified inoculation method for the preparation of rabbit VX２hepatic carcinoma model and DSA imagining observation[J].journal interventional radiology,2010,(08):214.
[9]贺洪德,贺晶,罗中华,等.肝动脉化疗栓塞联合门静脉栓塞治疗中晚期肝癌的疗效评价[J].介入放射学杂志,2010,(03):191.
　HE Hongde,HE Jing,LUO Zhonghua,et al.Evaluation of the therapeutic effect of hepatic arterial chemoembolization combined with portal chemoembolization for advanced hepatic carcinomas[J].journal interventional radiology,2010,(08):191.
[10]李广琪,曹玮,李超,等.肝动脉热灌注对兔肝VX２肿瘤及正常肝组织血管渗透性功能的作用[J].介入放射学杂志,2010,(03):217.
　LI Guangqi,CAO Wei,LI Chao,et al.Influence of hepatic artery thermotherapy on the vascular permeability of hepatic tumor tissue and normal liver tissue in VX２tumor－bearing rabbits[J].journal interventional radiology,2010,(08):217.

备注/Memo

备注/Memo:
收稿日期：２０１０－０２－２５
更新日期/Last Update: 2010-08-15