[1]林剑平,先正元,石荣书,等.DSA引导下犬肾微波消融局部损伤作用的实验研究[J].介入放射学杂志,2008,(09):651.
　LIN Jianping,XIAN Zhengyuan,SHI Rongshu,et al.Experimental research on local renal injury of dog with microwave ablation guided by DSA[J].journal interventional radiology,2008,(09):651.
点击复制

DSA引导下犬肾微波消融局部损伤作用的实验研究()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年09期
页码:
651
栏目:
实验研究
出版日期:
2008-09-15

文章信息/Info

Title:
Experimental research on local renal injury of dog with microwave ablation guided by DSA
作者:
林剑平; 先正元; 石荣书; 等
０１７０００内蒙古鄂尔多斯市中心医院放射科（林剑平）；遵义医学院影像系（先正元）；遵义医学院附属医院介入中心（石荣书）；CT室（张高峰、李先浪）
Author(s):
LIN Jian－ping; XIAN Zheng－yuan; SHI Rong－shu; ZHANG Gao－feng; LI Xian－lang．
Department of Radiology，Erdos Central Hospital，Inner Mongolia０１７０００，China
关键词:
微波消融; 肾损伤; 肾功能; 并发症; 数字减影; 血管造影
分类号:
R７３.３３
文献标志码:
A
摘要:
目的探讨DSA引导下微波消融治疗肾脏病变的效果、安全性及保存部分肾功能的可行性。方法对肾盂内注入３０％泛影葡胺的新鲜离体猪肾和行动脉肾盂造影的活犬肾进行微波消融。将犬分为消融测温、双肾单点消融、单肾双点消融组。消融测温组消融后即时DSA造影，取病理。双肾单点消融与单肾双点消融组消融后即时与１０d后DSA造影，取尿常规、血常规、肾功能和病理检查。结果①离体实验均显示肾盂挛缩显著，７０W、３min功率消融易产生尿漏。②活体实验DSA示局部血液供应消失，残余肾功能与消融面积相关。急性期病理结果示肾皮质、肾髓质、肾盂细胞急性损伤。慢性期DSA示肾消融区大小无明显变化，消融区外大血管及肾组织血供正常，残余肾功能存在，无尿漏。右肾上极消融与周围脏器产生粘连。肾大体标本示肾被膜增厚。显微镜下显示凝固性坏死，边界纤维组织增生。结论微波消融能有效地灭活局部肾组织，对残余肾的功能保留效果好；无大血管损伤，慢性期无尿漏发生，较易引起肾周围组织粘连

参考文献/References:

［１］Murphy DP，Gill IS．Energy based renal tumor ablation，a review［J］．Semi n Urol Oncol，２００１，１９：１３３－１４０．
［２］Kigure T，Harada T，Yuri Y，et al．Ultrasound－guided micro－wave thermotherapy on a VX－２carcinoma implanted in rabbit kidney［J］．Ultrasound Med Biol，１９９５，２１：６４９－６５５．
［３］He X，McGee S，Coad JE，et al．Investigation of the thermal and tissue injury behaviour in microwave thermal therapy using a porcine kidney model［J］．Int J Hyperthermia，２００４，２０：５６７－５９３．
［４］梁萍，董宝玮，董隽，等．超声引导下经皮微波凝固治疗肾肿瘤１例［J］．中华超声影像学杂志，２００３，１２：４４５－４４６．
［５］张大鵾，董宝玮，梁萍，等．植入式微波消融离体猪肾实验研究［J］．中国医学影像技术，２００６，２２：１６１４－１６１６．
［６］邢金春，张开颜．冷冻和射频治疗对猪肾盂肾盏肾段血管的损伤作用［J］．中华实验外科杂志，２００５，２２：８６２－８６３．
［７］Rendon RA，Gertner MR，Sherar MD，et al．Development of a radiofrequency based thermal therapy technique in an in vivo porcine model for the treatment of small renal masses［J］．J Urol，２００１，１６６：２９２－２９８．

相似文献/References:

[1]许彪,刘剔生,文斌.超选择肾动脉栓塞治疗外伤性肾出血：３８例报告[J].介入放射学杂志,2008,(01):60.
　XU Biao,LIU Tisheng,WENG Bing.Superselective renal artery embolization for traumatic renal hemorrhage：report of ３８cases[J].journal interventional radiology,2008,(09):60.
[2]刘冲,何金瞳,李天,等.水隔离技术对降低肝被膜下肿瘤微波消融术后残存的效果评价 [J].介入放射学杂志,2020,29(03):267.
　LIU Chong,HE Jintong,LI Tian,et al.Application of hydrodissection technique in reducing residual tumor tissue of hepatic subcapsular malignancy after microwave ablation and evaluation of its curative effect[J].journal interventional radiology,2020,29(09):267.
[3]王智,池嘉昌,翟博.超声引导下经皮微波消融治疗膈顶部肝癌的疗效观察 [J].介入放射学杂志,2020,29(03):305.
　WANG Zhi,CHI Jiachang,ZHAI Bo..Ultrasound-guided percutaneous microwave ablation for the treatment of hepatocellular carcinoma adjacent to diaphragmatic dome[J].journal interventional radiology,2020,29(09):305.
[4]田 玮,陆海燕.1例脾肿瘤消融术后并发血象异常患者的护理[J].介入放射学杂志,2021,30(02):214.
　TIAN Wei,LU Haiyan..Nursing care for a patient with abnormal hemogram after receiving microwave ablation for splenic tumor[J].journal interventional radiology,2021,30(09):214.
[5]顾美琴,奚 静,李 尊,等.超声引导下微波消融治疗多灶性T1N0M0甲状腺乳头状癌的可行性研究[J].介入放射学杂志,2024,33(05):495.
　GU Meiqin,XI Jing,LI Zun,et al.Ultrasound- guided microwave ablation for multifocal T1N0M0 papillary thyroid carcinoma： a feasibility study[J].journal interventional radiology,2024,33(09):495.
[6]秦焕蓉,程芝梅,吴祥锴,等.经导管动脉化疗栓塞和微波消融治疗VX2肝癌诱导低氧诱导因子-1α调节糖酵解与微血管密度相关性分析研究[J].介入放射学杂志,2024,33(04):390.
　QIN Huanrong,CHENG Zhimei,WU Xiangkai,et al.Correlation between HIF-1α regulation of glycolysis and microvessel density induced by transcatheter arterial chemoembolization and microwave ablation in experimental rabbits with VX2 hepatocellular carcinoma[J].journal interventional radiology,2024,33(09):390.

备注/Memo

备注/Memo:
收稿日期：２００８－０２－２６
更新日期/Last Update: 2008-09-15