[1]王智,池嘉昌,翟博.超声引导下经皮微波消融治疗膈顶部肝癌的疗效观察 [J].介入放射学杂志,2020,29(03):305-309.
 WANG Zhi,CHI Jiachang,ZHAI Bo..Ultrasound-guided percutaneous microwave ablation for the treatment of hepatocellular carcinoma adjacent to diaphragmatic dome[J].journal interventional radiology,2020,29(03):305-309.
点击复制

超声引导下经皮微波消融治疗膈顶部肝癌的疗效观察
()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年03
页码:
305-309
栏目:
临床研究
出版日期:
2020-04-20

文章信息/Info

Title:
Ultrasound-guided percutaneous microwave ablation for the treatment of hepatocellular carcinoma adjacent to diaphragmatic dome
作者:
王智池嘉昌翟博
Author(s):
WANG Zhi CHI Jiachang ZHAI Bo.
Department of Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
关键词:
【关键词】 原发性肝癌膈顶肿瘤微波消融B超引导
文献标志码:
A
摘要:
【摘要】 目的?探讨超声引导下经皮微波消融(MWA)治疗膈顶部肝肿瘤的疗效及应用价值。方法?对2011年3月—2017年12月期间接受超声引导下MWA治疗的133例隔顶部肝癌患者(A组)及同期接受治疗的136例肝癌患者(B组)的临床资料进行回顾性分析,总结超声引导下经皮MWA治疗膈顶部肝肿瘤的技术路线、临床疗效及安全性。结果?MWA治疗后,A、B组的完全消融率分别为88.7%和95.6%,A组患者的完全消融率明显低于B组(P=0.036)。两组间严重并发症的发生率差异无统计学意义(P>0.05)。A组患者术后6个月、12个月无复发生存率分别为53.5%和39.0%,术后12个月、24个月、36个月生存率分别为80.8%、57.7%和50.3%。B组患者术后6个月、12个月无复发生存率分别为69.0%和57.8%,术后12个月、24个月、36个月生存率分别为92.1%、77.8%和71.9%。B组患者的无瘤生存率和总生存率明显高于A组,差异有显著统计学意义(P<0.01)。结论?尽管膈顶部肿瘤位置的特殊性影响MWA的治疗效果,且术后更易复发,但膈顶部肿瘤并非MWA的禁忌证,MWA仍是治疗膈顶部肝癌的一种安全有效的治疗方法。

参考文献/References:

[1] 中华人民共和国卫生和计划生育委员会医政医管局. 原发性肝癌诊疗规范(2017年版)[J]. 中华消化外科杂志, 2017, 16:635-647.
[2] Shiina S, Tateishi R, Arano T, et al. Radiofrequency ablation for hepatocellular carcinoma: 10-year outcome and prognostic factors[J]. Am J Gastroenterol, 2012, 107: 569-577.
[3] Ren H, An C, Liang P, et al. Ultrasound-guided percutaneous microwave ablation assisted by athree-dimensional visualization treatment platform combined with transcatheter arterial chemoembolization for a single large hepatocellular carcinoma 5 cm or larger: a preliminary clinical application[J]. Int J Hyperthermia, 2018:1-11.
[4] Ma S, Ding M, Li J, et al. Ultrasound-guided percutaneous microwave ablation for hepatocellular carcinoma: clinical outcomes and prognostic factors[J]. J Cancer Res Clin Oncol, 2017, 143: 131-142.
[5] 周平盛, 王延明, 钱国军, 等. 微波消融治疗单发5cm下肝细胞肝癌预后及其影响因素分析[J]. 介入放射学杂志, 2017, 26:712-717.
[6] 程馨玉, 丁建民, 经?翔. 影响原发性肝癌射频消融治疗预后的因
素[J]. 中国介入影像与治疗学, 2015, 12:18-21.
[7] Kambadakone A, Baliyan V, Kordbacheh H, et al. Imaging guided percutaneous interventions in hepatic dome lesions: tips and tricks[J]. World J Hepatol, 2017, 9:840-849.
[8] 中国抗癌协会肝癌专业委员会, 中国抗癌协会临床肿瘤学协作专业委员会, 中华医学会肝病学分会肝癌学组. 肝癌局部消融治疗规范的专家共识[J]. 肿瘤, 2011, 31:385-358.
[9] 翟?博, 李晓燕, 刘?晟, 等. 膈顶部原发性肝癌的射频消融[J]. 介入放射学杂志, 2009, 18:357-361.
[10] 经?翔, 陈敏华. 肝肿瘤热消融治疗并发症原因及其防治[J]. 中华医学杂志, 2015, 95:2147-2149.
[11] 韩?玥. 肝脏肿瘤热消融治疗的并发症病因及防治策略[J]. 肝癌电子杂志, 2014, 1:13-16.
[12] 刘丽莉, 方?勇, 王凯峰, 等. 引导射频消融治疗膈顶部肝癌的临床研究[J]. 肿瘤, 2014, 34:60-66.
[13] 朱传东, 丁怀银, 王礼学, 等. CT 引导下经皮微波消融治疗膈顶部复发性小肝癌15 例疗效观察[J]. 现代肿瘤医学, 2018, 26:733-736.
[14] 唐?田, 古善智, 李国文, 等. 超声引导联合人工胸水微波消融膈顶部肝肿瘤[J]. 中南大学学报?医学版, 2017, 42:184-188.
[15] 韩?玥, 张?景, 闫?东, 等. 人工气胸在CT 引导下肝脏膈顶肿瘤微波消融中的应用[J]. 中国医学前沿杂志?电子版, 2017, 9:119-122.


相似文献/References:

[1]高 嵩,朱旭,杨仁杰,等. TACE联合奥沙利铂、氟尿嘧啶、亚叶酸钙肝动脉化疗治疗中晚期原发性肝癌[J].介入放射学杂志,2012,(05):377.
 ,,et al. TACE combined with hepatic arterial infusion chemotherapy using oxaliplatin, 5fluorouracil and folinic acid for intermediate and advanced hepatocellular carcinomas[J].journal interventional radiology,2012,(03):377.
[2]程洪涛,郭晨阳,黎海亮,等.TACE联合射频消融治疗原发性肝癌疗效的影响因素分析[J].介入放射学杂志,2012,(03):216.
 ,,et al.TACE combined with CTguided percutaneous radiofrequency ablation for the treatment of primary hepatocellular carcinomas: an analysis of factors affecting the therapeutic result [J].journal interventional radiology,2012,(03):216.
[3]张晓前,郭 鹏,党之俊,等.金龙胶囊联合介入疗法治疗原发性肝癌临床观察[J].介入放射学杂志,2012,(03):249.
 ,,et al.Kinglong capsules combined with interventional therapy for hepatocellular carcinomas: clinical observation [J].journal interventional radiology,2012,(03):249.
[4]姚红响,陈根生,诸葛英,等.肝动脉化疗栓塞联合CT引导射频消融序贯治疗中小肝癌的临床应用[J].介入放射学杂志,2012,(04):301.
 ,,et al.Sequential treatment with TACE and CTguided RFA for small and moderate sized HCC [J].journal interventional radiology,2012,(03):301.
[5]姚全军,胡鸿涛,黎海亮,等.C臂CT成像在乏血供原发性肝癌诊疗中的临床应用[J].介入放射学杂志,2012,(04):305.
 ,,et al.The clinical application of C arm CT imaging in diagnosing and treating hypovascular primary hepatic carcinomas [J].journal interventional radiology,2012,(03):305.
[6]刘 昕,吕维富,鲁 东,等. 动脉介入栓塞治疗肝癌破裂出血[J].介入放射学杂志,2012,(07):586.
 LIU Xin,LV Wei- fu,LU Dong,et al. Interventional treatment of hepatic bleeding due to spontaneous rupture of hepatocellular carcinoma[J].journal interventional radiology,2012,(03):586.
[7]张志良,杨学东,温阿明,等. 经动脉化疗栓塞联合伽玛刀治疗原发性肝癌的疗效评价[J].介入放射学杂志,2012,(07):596.
 ZHANG Zhi- liang,YANG Xue- dong,WEN A-ming,et al. Evaluation of TACE combined with gamma?蛳 knife radiotherapy for primary hepatocellular carcinoma[J].journal interventional radiology,2012,(03):596.
[8]赵许亚,周 石.TACE联合经皮瘤内注射碘油吡柔比星乳剂治疗中晚期肝癌疗效分析[J].介入放射学杂志,2012,(08):675.
 ZHAO Xu- ya,ZHOU Shi.. Transcatheter artery chemoembolization combined with percutaneous intratumoral injection of Lipiodol emulsion of pirarubicin for advanced hepatocellular carcinomas: an analysis of clinical efficacy[J].journal interventional radiology,2012,(03):675.
[9]王少雷,李 森,魏 宏,等.奥沙利铂与吡喃阿霉素介入治疗原发性肝癌的比较研究[J].介入放射学杂志,2012,(09):738.
 WANG Shao- lei,LI Sen,WEI Hong,et al. Interventional chemoembolization therapy of primary hepatocellular carcinoma: a comparative study between oxaliplatin and therarubicin[J].journal interventional radiology,2012,(03):738.
[10]骆俊朋,胡鸿涛,郭晨阳,等.吉西他滨热化疗灌注联合卡铂化疗栓塞治疗原发性肝癌临床应用研究[J].介入放射学杂志,2013,(06):470.
 LUO Jun? peng,HU Hong? tao,GUO Chen? yang,et al. Hyperthermochemotherapy by using heated gemcitabine perfusion combined with transcatheter arterial chemoembolization of carboplatin for primary liver carcinomas[J].journal interventional radiology,2013,(03):470.

备注/Memo

备注/Memo:
(收稿日期:2019-05-17)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2020-04-16