[1]邵天朋,刘 丽,袁 磊,等.动脉栓塞联合氩氦刀序贯治疗小肾癌的临床疗效分析[J].介入放射学杂志,2015,(07):597-601.
 SHAO Tian- peng,LIU Li,YUAN Lei,et al.Sequential therapy of transcatheter arterial embolization combined with percutaneous argon- helium cryoablation for small renal cancers: analysis of clinical effect[J].journal interventional radiology,2015,(07):597-601.
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动脉栓塞联合氩氦刀序贯治疗小肾癌的临床疗效分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年07期
页码:
597-601
栏目:
肿瘤介入
出版日期:
2015-07-25

文章信息/Info

Title:
Sequential therapy of transcatheter arterial embolization combined with percutaneous argon- helium cryoablation for small renal cancers: analysis of clinical effect
作者:
邵天朋 刘 丽 袁 磊 卢光明 曹建民 许 健
Author(s):
SHAO Tian- peng LIU Li YUAN Lei LU Guang- ming CAO Jian- min XU Jian
Postgraduate School, Xuzhou Medical College, Xuzhou, Jiangsu Province 221000, China
关键词:
【关键词】 小肾癌 冷冻消融 动脉栓塞 并发症
文献标志码:
A
摘要:
【摘要】 目的 探讨动脉栓塞(TAE)联合CT引导经皮氩氦刀序贯治疗小肾癌的安全性和疗效。方法 收集2008年2月—2013年7月南京军区南京总医院医学影像科介入病房44例TAE联合CT引导经皮氩氦刀序贯治疗的小肾癌患者,术后1个月复查肾功能,术后1~3个月复查增强CT或增强MRI,采用mRECIST标准评价其疗效,并对患者进行12~46个月随访,平均随访时间28个月。结果 44例患者共48个病灶行TAE和氩氦刀序贯治疗,其中病灶完全缓解(CR)38个,部分缓解(PR)6个,病灶稳定(SD)4个,缓解率(CR+PR)为91.7%。所有患者均未发生严重并发症,仅1例患者冷冻过程中出现局限性出血,给予对症处理后好转。患者术后平均住院时间4 d,随访期间3例失访,1例因食管癌相关并发症死亡。40例患者随访期均存活,存活患者中5例于13~22个月后复发,后予以再次联合治疗。结论 采用TAE联合CT引导经皮氩氦刀序贯治疗小肾癌微创、安全、有效,尤其是氩氦刀冷冻前进行栓塞可能降低冷冻过程中出血发生率,值得临床推广应用。

参考文献/References:

[1] 那彦群, 叶章群, 孙颖浩, 等. 中国泌尿外科疾病诊断治疗指南(2014版)[M]. 北京: 人民卫生出版社, 2014: 3- 19.
[2] Ljungberg B, Hanbury DC, Kuczyk MA, et al. Renal cell carcinoma guideline[J]. Eur Urol, 2007, 51: 1502- 1510.
[3] Strom KH, Derweesh I, Stroup SP, et al. Second prize: Recur- rence rates after percutaneous and laparoscopic renal cryoablation of small renal masses: does the approach make a difference[J]. J Endourol, 2011, 25: 371- 375.
[4] 许 健, 曹建民, 卢光明, 等. CT引导下经皮穿刺氩氦刀靶向冷冻治疗肾癌[J]. 介入放射学杂志, 2008, 17: 667- 669.
[5] Lencioni R, Llovet JM. Modified RECIST(mRECIST) assessment for hepatocellular carcinoma[J]. Semin Liver Dis, 2010, 30: 52- 60.
[6] Siegel R, Ma J, Zou Z, et al. Cancer statistics, 2014[J]. CA Cancer J Clin, 2014, 64: 9- 29.
[7] 李 恒, 叶章群. 冷冻消融在肾肿瘤治疗中的应用[J]. 现代泌尿生殖肿瘤杂志, 2011, 3: 240- 242.
[8] Klatte T, Grubmüller B, Waldert M, et al. Laparoscopic cryoablation versus partial nephrectomy for the treatment of small renal masses: systematic review and cumulative analysis of observational studies[J]. Eur Urol, 2011, 60: 435- 443.
[9] Kapoor A, Touma NJ, Dib RE. Review of the efficacy and safety of cryoablation for the treatment of small renal masses[J]. Can Urol Assoc J, 2013, 7: E38- E44.
[10] Kunkle D, Uzzo RG. Cryoablation or radiofrequency ablation of the small renal mass: a meta- analysis[J]. Cancer, 2008, 113: 2671- 2680.
[11] Lin YC, Turna B, Frota R, et al. Laparoscopic partial nephrectomy versus laparoscopic cryoablation for multiple ipsilateral renal tumors[J]. Eur Urol, 2008, 53: 1210- 1218.
[12] Hinshaw JL, Shadid AM, Nakada SY, et al. Comparison of percutaneous and laparoscopic cryoablation for the treatment of solid renal masses[J]. AJR Am J Roentgenol, 2008, 191: 1159- 1168.
[13] Sidana A, Aggarwal P, Feng Z, et al. Complications of renal cryoablation: a single center experience[J]. J Urol, 2010, 184: 42- 47.
[14] Kim EH, Tanagho YS, Saad NE, et al. Comparison of laparos- copic and percutaneous cryoablation for treatment of renal masses[J]. Urology, 2014, 83: 1081- 1087.
[15] 任 超, 肖越勇, 吴 斌, 等. CT引导下经皮穿刺氩氦刀冷冻消融术治疗肾癌的临床应用研究[J]. 中华临床医师杂志? 电子版, 2012, 6: 58- 60.
[16] Li Y, Guo Z, Liu CF, et al. Effect of transcatheter renal arterial embolization combined with cryoablation on regulatory CD4(+)CD25(+) T lymphocytes in the peripheral blood of patients with advanced renal carcinoma[J]. Cryobiology, 2012, 65: 56- 59.
[17] Miller JM, Julien P, Wachsman A, et al. The role of embolization in reducing the complications of cryoablation in renal cell carcinoma[J]. Clin Radiol, 2014, 69: 1045- 1049.

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备注/Memo

备注/Memo:
(收稿日期:2014-08-25)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2015-07-22