[1]涂建飞,孙宏涛,孙 蓬,等.TraSphere显影栓塞微球用于经动脉化疗栓塞肝癌的疗效[J].介入放射学杂志,2026,(03):319-323.[doi:10.3969/j.issn.1008-794X.2026.03.015]
 TU Jianfei,SUN Hongtao,SUN Peng,et al.First-in-man study of TraSphere embolic microspheres for transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma[J].J Intervent Med,2026,(03):319-323.[doi:10.3969/j.issn.1008-794X.2026.03.015]
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TraSphere显影栓塞微球用于经动脉化疗栓塞肝癌的疗效()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2026年03
页码:
319-323
栏目:
临床研究
出版日期:
2026-03-25

文章信息/Info

Title:
First-in-man study of TraSphere embolic microspheres for transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma
文章编号:
1008-794X(2026)-003-0319-05
作者:
涂建飞 孙宏涛 孙 蓬 纪建松
323000 浙江丽水 丽水市中心医院(温州医科大学附属第五医院)介入诊疗中心(纪建松、涂建飞); 科睿驰(深圳)医疗科技发展有限公司(孙宏涛、孙 蓬)
Author(s):
TU JianfeiSUN HongtaoSUN PengJI Jiansong.
Lishui Municipal Central Hospital,Lishui,Zhejiang Province 323000,China; Cardiolink Science(Shenzhen)Med Tech Development Co.,Ltd.Shenzhen,Guangdong Province 518122,China.
关键词:
肝癌 载药微球经动脉化疗栓塞 显影栓塞微球 CT 可视化
分类号:
R735.7
DOI:
10.3969/j.issn.1008-794X.2026.03.015
文献标志码:
B
摘要:
目的 探讨TraSphere显影栓塞微球用于经动脉化疗栓塞治疗肝癌的安全性、有效性。方法 选取2023年9月至2023年11月丽水市中心医院收治的肝癌患者5例,以TraSphere显影栓塞微球加载表阿霉素行载药微球经动脉化疗栓塞(drug-eluting bead transarterial chemoembolization,DEB-TACE)治疗。治疗后随访1个月,根据改良实体瘤疗效评价标准(mRECIST)评价抗肿瘤疗效,记录栓塞区域可视化情况、肝功能及并发症。结果 5例患者均成功进行DEB-TACE治疗。治疗后1个月,5例患者病灶评价为PR。术后即刻锥形束CT扫描与术后1个月CT对栓塞区域的可视化评价中,100%病灶可达到25%~100%区域显影; 术后4例患者出现不良反应,其中栓塞后综合征3例,未发生3级以上不良反应,不良反应在给予对症支持治疗后,1~2 d内症状消失。结论 TraSphere显影栓塞微球用于DEB-TACE治疗肝癌安全可行,具有一定的短期疗效与较好的显影性能,远期疗效需大样本、多中心、随机对照研究进一步确证。

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(收稿日期:2025-01-14)
(本文编辑:新 宇)

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备注/Memo

备注/Memo:
通信作者: 纪建松 E-mail:jjstcty@wmu.edu.cn
更新日期/Last Update: 2026-03-25