[1]杨呈伟,冷晓畅,邵姝婧,等.基于计算流体力学的主动脉夹层术后假腔变化研究[J].介入放射学杂志,2026,(02):155-160.[doi:10.3969/j.issn.1008-794X.2026.02.007 ]
 YANG Chengwei,LENG Xiaochang,SHAO Shujing,et al.Study of the postoperative changes of false lumen volume in aortic dissection based on computational fluid dynamics[J].J Intervent Med,2026,(02):155-160.[doi:10.3969/j.issn.1008-794X.2026.02.007 ]
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基于计算流体力学的主动脉夹层术后假腔变化研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2026年02
页码:
155-160
栏目:
血管介入
出版日期:
2026-02-25

文章信息/Info

Title:
Study of the postoperative changes of false lumen volume in aortic dissection based on computational fluid dynamics
文章编号:
1008-794X(2026)-002-0155-06
作者:
杨呈伟 冷晓畅 邵姝婧 齐伟伟 钱沛东 黄连军 徐 磊
通信作者: 黄连军 E-mail:huanglianjun@126.com
Author(s):
YANG Chengwei12LENG Xiaochang3SHAO Shujing3QI Weiwei1QIAN Peidong3HUANG Lianjun1XU Lei2.
1Department of Imaging and Interventional Therapy,Shanghai Delta Cardiovascular Hospital,Shanghai 201702,China; 2Department of Medical Imaging,Affiliated Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China; 3Department of Technology Boea Wisdom(Hangzhou)Network Technology Co.,Ltd.Hangzhou,Zhejiang Province 310000,China
关键词:
主动脉夹层假腔 计算流体力学 形态学
分类号:
R654.3
DOI:
10.3969/j.issn.1008-794X.2026.02.007
文献标志码:
A
摘要:
目的 结合主动脉CT血管造影(CTA)形态学与计算流体动力学(computational fluid dynamics,CFD)分析,探究主动脉夹层术后假腔体积(false lumen volume,FLV)演变的血流动力学机制。方法 回顾性分析6例主动脉夹层术后患者共21次CTA随访资料,分析随访节点假腔形态学参数与CFD参数的关系。形态学参数包括:FLV、假腔短轴直径(false lumen short-axis diameter,FLSD)、长轴直径(false lumen long-axis diameter,FLLA)、真腔最窄水平假腔面积(false lumen area at the true lumen's narrowest point,FLA_TLS); CFD参数包括:时均壁面剪应力(time-averaged wall shear stress,TAWSS)、振荡剪切指数(oscillatory shear index,OSI)、相对停留时间(relative residence time,RRT)、梯度振荡数(gradient oscillatory number,GON)。结果 6例患者假腔扩张组与缩小组各3例,随访时间(138.7±121.0)d。FLV与形态学参数(FLSD:r=0.681,P=0.000 7; FLLA:r=0.874,P<0.000 1; FLA_TLS:r=0.80,P<0.000 1)及CFD参数高值区面积(高TAWSS:r=0.68,P=0.000 8; 高RRT:r=0.511,P<0.017 9; 高OSI:r=0.808,P<0.000 1; 高GON:r=0.793,P<0.000 1)均呈显著正相关。假腔缩小组TAWSS、RRT、OSI高值区占比增加; 扩张组则表现为假腔近心端入口高速射流、远端血流停滞,且TAWSS、RRT、OSI高值区占比减少。结论 血流动力学参数(TAWSS、OSI、RRT)与假腔演变显著相关,高OSI、低TAWSS和低RRT是主动脉夹层术后假腔扩张的关键机制。

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备注/Memo

备注/Memo:
基金项目: 上海市青浦区卫生健康系统第五轮特色专科建设(TZ2023-13); 上海市青浦区卫健委科研课题立项(QWJ2023-59)
通信作者: 黄连军 E-mail:huanglianjun@126.com
更新日期/Last Update: 2026-02-25