[1]李华伟,张庆桥,徐 浩,等.JAK2V617F基因突变与非突变布-加综合征患者介入术后再狭窄对比观察 [J].介入放射学杂志,2020,29(12):1196-1199.
　LI Huawei,ZHANG Qingqiao,XU Hao,et al.Postoperative restenosis of Budd-Chiari syndrome after interventional treatment：comparison between patients with JAK2V617F gene mutation and patients with no JAK2V617F gene mutation[J].journal interventional radiology,2020,29(12):1196-1199.
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JAK2V617F基因突变与非突变布-加综合征患者介入术后再狭窄对比观察


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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年12
页码:
1196-1199
栏目:
血管介入
出版日期:
2020-12-25

文章信息/Info

Title:
Postoperative restenosis of Budd-Chiari syndrome after interventional treatment：comparison between patients with JAK2V617F gene mutation and patients with no JAK2V617F gene mutation
作者:
李华伟;  张庆桥;  徐 浩;  祖茂衡;  肖晋昌;  神 斌;  杨 晶
Author(s):
LI Huawei;  ZHANG Qingqiao;  XU Hao;  ZU Maoheng;  XIAO Jinchang;  SHEN Bin;  YANG Jing.
Department of Interventional Radiology， Affiliated Hospital of Xuzhou Medical University， Xuzhou， Jiangsu Province 221006， China
关键词:
【关键词】 布-加综合征;  JAK2V617F基因突变;  再狭窄
文献标志码:
A
摘要:
【摘要】 目的 探讨JAK2V617F基因突变对布-加综合征（BCS）患者介入术后再狭窄的影响。方法 回顾性分析2015年1月至2019年9月在徐州医科大学附属医院接受介入术治疗的JAK2V617F基因突变BCS患者（突变组，n=18）和非突变BCS患者（对照组，n=36）临床资料，比较两组患者基线数据和介入术后再狭窄率。 结果 突变组血小板计数、凝血酶原时间、活化部分凝血活酶时间及国际标准化比值均高于对照组（P＜0.05）。突变组介入术后患者再狭窄率显著高于对照组（43.8%对13.9%，P=0.037）。突变组和对照组患者介入术后1、2、3年首次通畅率分别为67.0%、67.0%、40.2%和93.8%、84.0%、78.8%，突变组患者首次通畅率均显著低于对照组（P=0.015）。 结论 JAK2V617F基因突变可能增加BCS患者介入术后再狭窄发生率。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：2019-11-10）
（本文编辑：边 佶）
更新日期/Last Update: 2020-12-16