[1]崔 宁,李晓群.经皮经肝双极射频消融导管恶性梗阻性黄疸20例 [J].介入放射学杂志,2014,(08):693-697.
 CUI Ning,LI Xiao qun..Percutaneous transhepatic bipolar radiofrequency catheter ablation for the treatment of malignant obstructive jaundice: preliminary experience in 20 cases[J].journal interventional radiology,2014,(08):693-697.
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经皮经肝双极射频消融导管恶性梗阻性黄疸20例 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年08期
页码:
693-697
栏目:
非血管介入
出版日期:
2014-08-25

文章信息/Info

Title:
Percutaneous transhepatic bipolar radiofrequency catheter ablation for the treatment of malignant obstructive jaundice: preliminary experience in 20 cases
作者:
崔 宁 李晓群
Author(s):
CUI Ning LI Xiao qun.
Interventional Treatment Center, Affiliated Taihe Hospital, Hubei Medical College, Shiyan City, Hubei Province 442000, China
关键词:
【关键词】 恶性胆道梗阻 胆管 导管 射频消融 支架
文献标志码:
A
摘要:

【摘要】 目的 探讨经皮经肝双极射频消融(RFA)导管治疗恶性梗阻性黄疸的可行性、安全性及初步疗效。方法 选取20例失去手术治疗机会的恶性胆道梗阻患者(其中2例胆道支架再堵塞),采用经皮经肝穿刺胆道路径双极RFA治疗,消融功率为5 ~ 12 W,单次消融时间为60 ~ 120 s,消融持续时间平均4.66 min(1.5 ~ 8.5 min),有效消融范围平均为5.76 cm(4 ~ 10 cm)。消融后导入球囊扩张阻塞段,再植入胆道金属支架,观察术后疗效、安全性及并发症。结果 20例患者均成功完成RFA治疗:17例植入胆道支架,其中11例支架植入前用球囊扩张;1例单行球囊扩张术未放置支架;2例胆道支架再阻塞后消融(1例球囊扩张)。术后未出现胆漏、胆道感染、肝贯通伤、腹膜炎等并发症。20例胆道引流均获成功;中位随访期为3个月(0.5 ~ 10个月);术后1、3个月分别有19例和14例支架通畅,术后1、3个月分别有19例和14例生存,随访期内,20例患者中8例生存,12例死亡。中位生存期为144 d(13 ~ 330 d),支架通畅中位时间为90 d(13 ~ 210 d)。12例死亡患者中8例因恶病质、多脏器功能衰竭死亡,但随访期内总胆红素等指标无升高。结论 经皮肝穿刺胆道内导管射频消融术作为一种新型安全、可行的治疗方法,取得了一定疗效,但远期疗效仍有待进一步探讨。

 

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备注/Memo

备注/Memo:
(收稿日期:2014-02-22)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-08-22