[1]李文会,罗剑钧,戴真煜,等.腔内近距离放疗联合及支架植入治疗恶性胆道梗阻[J].介入放射学杂志,2015,(03):215-218.
 LI Wen hui,LUO Jian jun,DAI Zhen yu,et al.Intraluminal brachytherapy combined with stent placement for the treatment of malignant biliary obstruction[J].journal interventional radiology,2015,(03):215-218.
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腔内近距离放疗联合及支架植入治疗恶性胆道梗阻 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年03期
页码:
215-218
栏目:
非血管介入
出版日期:
2015-03-25

文章信息/Info

Title:
Intraluminal brachytherapy combined with stent placement for the treatment of malignant biliary obstruction
作者:
李文会 罗剑钧 戴真煜 姚立正 董从松 朱 军 薄顺挺
Author(s):
LI Wen hui LUO Jian jun DAI Zhen yu YAO Li zheng DONG Cong song ZHU Jun BO Shun ting.
Department of Radiology, Affiliated Yancheng Municipal Third People’s Hospital, Southeast University, Yancheng, Jiangsu Province 224001, China
关键词:
【关键词】 恶性胆道梗阻 支架 碘-125粒子 近程放疗
文献标志码:
A
摘要:
【摘要】 目的 评价经皮植入125I粒子条及支架治疗恶性胆道梗阻的安全性及疗效。方法 对2009年6月至2013年6月,在上海中山医院接受介入治疗的68例恶性胆道梗阻患者的资料进行回顾性分析,其中41例在胆道梗阻段同时植入支架和125I粒子条(联合治疗组),27例仅植入支架(传统治疗组),对两组患者的生存期、至黄疸进展时间及手术相关不良事件发生率进行比较。结果 所有125I粒子条和支架植入均获成功。传统支架组和联合支架组术后7、14 d血清胆红素水平组间差异有统计学意义(P < 0.05);联合支架组术后未发生明显骨髓抑制;单纯支架组和联合支架组中位生存期分别为123和215 d,差异有统计学意义(P < 0.05)。结论 腔内近程放疗联合支架植入治疗恶性胆道梗阻安全,疗效较单纯植入支架明显。

参考文献/References:

[1] 罗开元, 毛文源, 等. 实用组织间植入内放射治疗恶性肿瘤学[M]. 北京: 人民卫生出版社, 2008.
[2] Cheng JL, Bruno MJ, Bergman JJ, et al. Endoscopic palliation of patients with biliary obstruction caused by nonresectable hilar cholangiocarcinoma: efficacy of self expandable metallic Walls tents[J]. Gastrointest Endosc, 2002, 56: 33 39.
[3] Hong K, Geschwind J. Locoregional intra arterial therapies for unresectable intrahepatic cholangiocarcinoma[J]. Semin Oncol, 2010, 37: 110 117.
[4] Kopek N, Holt MI, Hansen AT, et al. Stereotactic body radiotherapy for unresectable cholangiocarcinoma[J]. Radiother Oncol, 2010, 94: 47 52.
[5] Shinohara ET, Guo M, Mitra N, et al. brachytherapy in the treatment of cholangiocarcinoma[J]. Int J Radiat Oncol Biol Phys, 2010, 78: 722 728.
[6] Válek V, Kysela P, Kala Z, et al. Brachytherapy and percutaneous stenting in the treatment of cholangiocarcinoma: A prospective randomised study[J]. Eur J Radiol, 2007, 62: 175 179.
[7] Simmons DT, Baron TH, Petersen BT, et al. A novel endoscopic approach to brachytherapy in the management of Hilar cholangiocarcinoma[J]. Am J Gastroenterol, 2006, 101: 1792 1796.
[8] Nag S, Dehaan M, Scruggs G, et al. Long term Follow Up of patients of intrahepatic malignancies treated with iodine 125 brachytherapy[J]. Int J Radiat Oncol Biol Phys, 2006, 64: 736 744.
[9] 贺克武, 高 斌, 秦汉林, 等. 125I粒子组织间植入联合支气管动脉灌注化疗治疗肺癌的疗效观察[J]. 介入放射学杂志, 2012, 21: 554 558.
[10] 戴真煜, 姚立正, 李文会, 等. 经皮胆道支架联合支架旁125I粒子条植入治疗恶性胆道梗阻[J]. 介入放射学杂志, 2011, 20: 706 708.
[11] 王 皓, 王俊杰, 袁慧书, 等. 放射性125I粒子植入治疗椎体及椎旁肿瘤[J]. 现代肿瘤医学, 2010, 18: 146 148.
[12] Zhu HD, Guo JH, Zhu GY, et al. A novel biliary stent loaded with (125)I seeds in patients with malignant biliary obstruction: preliminary results versus a conventional biliary stent[J]. J Hepatol, 2012, 56: 1104 1111.
[13] Bethge N, Sommer A, Gross U, et al. Human tissue responses to metal stents implanted in vivo for the palliation of malignant stenoses[J]. Gastrointest Endosc, 1996, 43: 596 602.
[14] Van Berkel AM, Huibregtse IL, Bergman JJ, et al. A prospective randomized trial of Tannenbaum type Teflon coated stents versus polyethylene stents for distal malignant biliary obstruction[J]. Eur J Gastroenterol Hepatol, 2004, 16: 213 217.

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备注/Memo

备注/Memo:
(收稿日期:2014-05-03)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2015-03-29