[1]纪昌学,陈宪,涂蓉,等.经肝动脉化疗栓塞对高危因素肝癌的疗效观察[J].介入放射学杂志,2007,(06):378.
　JI Chang-xue,CHEN Xian,TU Rong,et al.Therapeutic efficacy of transcatheter arterial chemoembolization for liver cancer with high-risk factors[J].journal interventional radiology,2007,(06):378.
点击复制

经肝动脉化疗栓塞对高危因素肝癌的疗效观察()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年06期
页码:
378
栏目:
肿瘤介入
出版日期:
2007-06-15

文章信息/Info

Title:
Therapeutic efficacy of transcatheter arterial chemoembolization for liver cancer with high-risk factors
作者:
纪昌学; 陈宪; 涂蓉; 等
５７０１０２海口海南医学院附属医院放射科（纪昌学、涂蓉）；武汉湖北省肿瘤医院放射科（陈宪、李子林）
Author(s):
JI Chang-xue; CHEN Xian; TU Rong; LI Zi-lin
Department of Radiology，Affiliated Hospital of Hainan Medical College，Haikou５７０１０２，China
关键词:
肝动脉化疗栓塞; 肝癌; 高危因素; 生存
分类号:
R７３５.７
文献标志码:
A
摘要:
目的探讨经肝动脉化疗栓塞（TACE）对高危因素肝癌的治疗效果。方法回顾性分析２００１年１月至２００５年１２月２６６例肝癌患者接受５３６次介入治疗，患有门静脉癌栓或血胆红素升高（＞３４μmol／L）者为高危组，余患者为低危组。高危组７４例（２７．８％），低危组１９２例。高危组采用更加超选择性栓塞、较少的栓塞剂用量和较少的手术次数（为１．４和２．３P＜０．０５），比较两组患者的术后并发症发生率、生存期。结果全部并发症的发生率为３．５％，两组并发症的发生率差异无统计学意义（分别为２．５和７．６％，P＝０．０７）熏高危组１、３年生存率分别为４５％和１６％，低危组１、３年生存率分别为６３％和１８％，低危组生存期长于高危组，但两组间差异无统计学意义（P＝０．０８）。结论高危因素肝癌患者TACE术后并发症发生率未显著增加。采用适当的技术，TACE对高危因素肝癌患者是安全的。

参考文献/References:

［１］Kiely JM，Rilling WS，Chemoembolization in patients at high risk：results and complications［J］．J Vasc Interv Radiol，２００６，１７：４７-５３．
［２］LiadL，Virgili J，Figueras J，et al．A prognostic index of the survival of patients with unresectable hepatocellular carcinoma after transcatheter arterial chemoembolization［J］．Cancer，２０００，８８：５０-５７．
［３］Okusaki T，Odada S，Ueno H，et al．Evaluation of the therapeutic effect of transcatheter arterial embolization for hepatocellular carcinoma［J］．Oncology，２０００，５８：２９３-２９９．
［４］Liovet JM，Bruix J．Systematic review of randomized trials for unresectable hepatocellular carcinoma：Chenmoembolization improves sruvival［J］．Hepatology，２００３，３７：４２９-４４２．
［５］Chan AO，Yuen MF，Hui CK，et al．A prospective study regard-ing the complications of transcatheter intraarterial lipiodol chemoembolization in patients with hepatocellular carcinoma［J］．Cancer，２００２，９４：１７４７-１７５２．
［６］罗鹏飞，符力，陈晓明，等．肝癌介入治疗后胆汁瘤的形成与临床意义［J］．中华放射学杂志，２０００，３４：７５７-７５９．
［７］Tazawa J，Maeda M，Sakai Y，et al．Radiation therapy in com-bination with transcathter arterial chemoembolization for hepatocellular carcinoma with extensive portal vein involvement［J］．J Gastroenterol Hepatol，２００１，１６：６６０-６６５．

相似文献/References:

[1]曹海利,孟巍,白彬.肝癌基因治疗研究新进展[J].介入放射学杂志,2008,(05):375.
　CAO Haili,MENG Wei,BAI Bin.New progress in research of gene therapy for hepatocellular carcinoma[J].journal interventional radiology,2008,(06):375.
[2]杨伟洪,刘鹏程,梁珊瑚,等.多层螺旋CT血管造影在判断肝癌寄生供血中的价值[J].介入放射学杂志,2008,(09):654.
　YANG Weihong,LIU Pengchen g,LIANG Shanhu,et al.Evaluation of MSCTA for parasitic blood supply in hepatic carcinoma[J].journal interventional radiology,2008,(06):654.
[3]张茵,周兵,许秀芳,等.肝动脉化疗栓塞治疗原发性肝癌存活２０年一例[J].介入放射学杂志,2008,(09):684.
　ZHANG Yin,ZHOU Bing,XU Xiufang,et al.Survival more than２０years after transarterial chemical embolization for hepatocellular carcinoma：A case report[J].journal interventional radiology,2008,(06):684.
[4]官泳松,贺庆.肝癌介入治疗中应用p５３的几个要点[J].介入放射学杂志,2008,(11):761.
　GUAN Yongsong,HE Qing.Essentials in clinical application of p５３for tumors intervention－example of liver cancer[J].journal interventional radiology,2008,(06):761.
[5]肖运平,肖恩华.介入治疗在防治肝癌术后复发中的作用及进展[J].介入放射学杂志,2008,(11):831.
　XIAO Yunping,XIAO Enhua.The role and progress of interventional therapy in the prevention and treatment of postoperative hepatocellular carcinoma recurrence[J].journal interventional radiology,2008,(06):831.
[6]史震山,陈自谦,杨熙章,等.原发性大肝癌患者TACE后S－腺苷蛋氨酸的护肝作用[J].介入放射学杂志,2008,(11):790.
　SHI Zhenshan,CHEN Ziqian,YANG Xizhang,et al.The clinical study on the liver－protection of S－adenosy－methionine in large hepatocellular carcinoma patients after TACE[J].journal interventional radiology,2008,(06):790.
[7]王耀普,杨康健,赵思源,等.兔肝癌模型的改良接种及其DSA影像分析[J].介入放射学杂志,2010,(03):214.
　WANG Yaopu,YANG Kangjian,ZHAO Siyuan,et al.The modified inoculation method for the preparation of rabbit VX２hepatic carcinoma model and DSA imagining observation[J].journal interventional radiology,2010,(06):214.
[8]贺洪德,贺晶,罗中华,等.肝动脉化疗栓塞联合门静脉栓塞治疗中晚期肝癌的疗效评价[J].介入放射学杂志,2010,(03):191.
　HE Hongde,HE Jing,LUO Zhonghua,et al.Evaluation of the therapeutic effect of hepatic arterial chemoembolization combined with portal chemoembolization for advanced hepatic carcinomas[J].journal interventional radiology,2010,(06):191.
[9]李广琪,曹玮,李超,等.肝动脉热灌注对兔肝VX２肿瘤及正常肝组织血管渗透性功能的作用[J].介入放射学杂志,2010,(03):217.
　LI Guangqi,CAO Wei,LI Chao,et al.Influence of hepatic artery thermotherapy on the vascular permeability of hepatic tumor tissue and normal liver tissue in VX２tumor－bearing rabbits[J].journal interventional radiology,2010,(06):217.
[10]杨康健,赵思源,赵斌羽,等.兔肝癌改良接种模型的生长特性研究[J].介入放射学杂志,2010,(03):211.
　YANG Kangjian,ZHAO Siyuan,ZHAO Binyu,et al.The growing features of rabbit VX２hepatic carcinoma model prepared with modified inoculation method[J].journal interventional radiology,2010,(06):211.
[11]陆骊工,胡宝山,李勇,等.中晚期原发性肝癌合并症的介入治疗研究[J].介入放射学杂志,2008,(07):514.
　LU Ligong,HU Baoshan,LI Yong,et al.Study of interventional therapy for complications in advanced primary hepatocellular carcinoma[J].journal interventional radiology,2008,(06):514.
[12]郑加生,李建军,崔雄伟,等.肝动脉化疗栓塞联合CT引导下射频消融术治疗肝癌的疗效分析[J].介入放射学杂志,2009,(05):324.
　ZHENG Jia-sheng,LI Jian-jun,CUI Xiong-wei,et al.Therapeutic combination of hepatic arterial chemoembolization with CT鄄guided radiofrequency ablation for hepatocellular carcinoma：an analysis of curative effect[J].journal interventional radiology,2009,(06):324.

备注/Memo

备注/Memo:
收稿日期：２００６－０４－２６
更新日期/Last Update: 2007-06-15