[1]周 兵,李明华,王建波,等.覆膜支架置入封堵治疗后动脉瘤形态学变化的实验研究[J].介入放射学杂志,2011,(02):131-134.
 ZHOU Bing,LI Ming-hua,WANG Jian-bo,et al.The morphologic changes of aneurysms after isolated by covered stent implantation: an experimental study[J].journal interventional radiology,2011,(02):131-134.
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覆膜支架置入封堵治疗后动脉瘤形态学变化的实验研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2011年02期
页码:
131-134
栏目:
实验研究
出版日期:
2011-03-15

文章信息/Info

Title:
The morphologic changes of aneurysms after isolated by covered stent implantation: an experimental study
作者:
周 兵 李明华 王建波 程永德 王 珏 袁建华
310014 杭州 浙江省人民医院放射科介入病房;上海交通大学附属第六人民医院;解放军第八五医院
Author(s):
ZHOU Bing LI Ming-hua WANG Jian-bo CHENG Yong-de WANG Jue YUAN Jian-hua.
Department of Interventional Radiology, Zhejiang Provincial People’s Hospital, Hangzhou 310014, China
关键词:
动脉瘤 覆膜支架 体积 占位效应
分类号:
R197.39
文献标志码:
A
摘要:
目的   研究颅内动脉瘤在使用覆膜支架治疗后的形态学变化。方法 使用5只实验犬建立双侧颈动脉侧壁动脉瘤模型10枚,2周后使用覆膜支架对动脉瘤进行封堵治疗。分别于术前、术后即刻、术后2、4周行动脉瘤3.0 MR检查,观察动脉瘤形态学变化,术后4周将实验动物处死后行病理学研究。重点研究覆膜支架置入后不同时期动脉瘤体积的变化。统计软件使用SAS6.12。结果 3.0 MR能够在T2像清楚显示动脉瘤形态。术前、术后即刻、术后2、4周动脉瘤瘤体积分别为(100.17 ± 16.64)mm3,(97.25 ± 17.18)mm3,(44.11 ± 5.96)mm3和(33.75 ± 5.02)mm3,支架置入后不同时间动脉瘤体积比较差异有统计学意义(χ2 = 22.254, P < 0.01);术后2、4周动脉瘤体积较术前平均减小55.6%,66.2%;术后4周病理显示动脉瘤体完全纤维化。结论 动脉瘤在覆膜支架封堵治疗后体积能够明显缩小并最终完全纤维化,从而减轻其对周围结构的占位效应。

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备注/Memo

备注/Memo:
收稿日期:20101018
更新日期/Last Update: 2011-03-15