[1]高飞,顾仰葵,黄金华,等.微波消融毁损活体猪脾的实验研究[J].介入放射学杂志,2010,(11):888-892.
　GAO Fei,GU Yang-kui,HUANG Jin-hua,et al.Destruction of porcine spleen with microwave ablation: an experimental study in vivo[J].journal interventional radiology,2010,(11):888-892.
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微波消融毁损活体猪脾的实验研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年11期
页码:
888-892
栏目:
实验研究
出版日期:
2010-11-25

文章信息/Info

Title:
Destruction of porcine spleen with microwave ablation: an experimental study in vivo
作者:
高飞; 顾仰葵; 黄金华; 罗荣光; 李常仑
510060  广州广州中山大学肿瘤医院影像与介入中心;华南肿瘤学国家重点实验室；南昌大学第一附属医院影像介入科
Author(s):
GAO Fei;  GU Yang-kui;  HUANG Jin-hua;  LUO Rong-guang;  LI Chang-lun.
Medical Imaging and Interventional Center, the Affiliated Cancer Hospital, Sun Yat-sen University, State Key Laboratory of Oncology in Southern China, Guangzhou 510060, China
关键词:
微波;  消融;  脾脏
分类号:
Ｒ５５１.１
文献标志码:
Ｂ
摘要:
目的探讨微波消融毁损淤血肿大的活体猪脾的安全性、可行性及其规律。方法麻醉并开腹分别结扎５头活猪脾静脉２～４ｈ，待脾脏淤血肿大后进行微波消融（共５６个位点），观察术中针道渗血、微波电极周围组织炭化情况，并记录不同功率、时间及消融部位对脾脏毁损体积的影响，同时观察消融术后消融灶及其周围组织的病理改变。结果消融术中针道渗血发生率为８．９％（５／５６），均为微波电极周围组织炭化所致；炭化发生率为８．９％（５／５６）；微波消融范围受消融功率、时间、部位的影响；消融范围与消融时间成正相关（ｒ＝０．９７５３６，Ｐ＜０．０１）；消融范围与消融功率成正相关（ｒ＝０．９８１８４，Ｐ＜０．０１）；远离脾门区域（Ⅱ区）消融范围明显大于靠近脾门区域（Ⅰ区）（Ｐ＜０．０１）；消融术后即时病理改变与１周后病理改变中均可见较大面积的凝固性坏死，后者坏死组织周边可见较明显的炎性反应及组织水肿改变。结论微波消融是一种毁损淤血肿大脾脏较为安全、可靠的微创方法，并可通过调整消融功率、时间、部位控制其毁损体积。

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备注/Memo

备注/Memo:
收稿日期：２０１００５１７
广东省科技计划项目（编号：2008B030301127）
更新日期/Last Update: 2010-11-25