[1]颜 波,吕朋华,王福安,等.胆道支架置入术联合125 I条以及肝动脉化疗栓塞术治疗恶性胆道梗阻[J].介入放射学杂志,2022,31(11):1085-1088.
 YAN Bo,LV Penghua,WANG Fuan,et al.Biliary stenting combined with 125I seed strip implantation and hepatic artery chemoembolization for malignant biliary obstruction[J].journal interventional radiology,2022,31(11):1085-1088.
点击复制

胆道支架置入术联合125 I条以及肝动脉化疗栓塞术治疗恶性胆道梗阻()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年11
页码:
1085-1088
栏目:
临床研究
出版日期:
2022-12-13

文章信息/Info

Title:
Biliary stenting combined with 125I seed strip implantation and hepatic artery chemoembolization for malignant biliary obstruction
作者:
颜 波 吕朋华 王福安 王书祥 孙 陵
Author(s):
YAN Bo LV Penghua WANG Fuan WANG Shuxiang SUN Ling.
Department of Interventional Radiology, North Jiangsu People’s Hospital, Yangzhou, Jiangsu Province 225001, China
关键词:
【关键词】 胆道支架125I 粒子 肝动脉化疗栓塞术 恶性胆道梗阻
文献标志码:
A
摘要:
【摘要】 目的 探讨胆道支架置入术联合125I条内照射以及肝动脉化疗栓塞术治疗恶性胆道梗阻的临床疗效。方法 回顾性分析2017年6月至2020年9月江苏省苏北人民医院治疗恶性胆道梗阻的患者共35例。所有患者首先在数字减影血管造影下经皮肝胆管引流(PTCD),12例患者行胆道支架植入治疗(对照组),23例患者接受经皮胆道支架置入术联合125I条以及肝动脉化疗栓塞术治疗(观察组)。结果 35例患者手术成功率为100%,术后两组均未发生与手术相关的严重并发症。观察组和对照组血清 TBil术后4周较术前明显下降,差异有统计学意义(P<0.05) 。术后,观察组胆道通畅时间为(6.50±0.34) 个月,长于对照组的(2.40±0.17)个月,差异有统计学意义(P<0.05);观察组与对照组患者中位生存时间分别为(7.20±0.48)个月和(2.40±0.17)个月,差异有统计学意义(P<0.05)。结论 胆道支架置入术联合125I条以及肝动脉化疗栓塞术治疗恶性胆道梗阻临床效果显著,能抑制肿瘤生长,延长支架开放时间及患者生存时间。

参考文献/References:

[1] 张小坚,张联合,张士良,等. 经内镜逆行胰胆管造影术与经皮肝穿刺胆道引流术治疗恶性梗阻性黄疸的比较[J]. 中华全科医学, 2016, 14:575- 577.
[2] Zhao SM,Zhao H,Gu WW,et al. Treatment of malignant obstructive jaundice by biliary stent and biliary stent combined with 125I seed implantation[J]. J Shanghai Jiaotong Univ(Sci), 2015, 35: 1661- 1665.
[3] Thornton RH, Frank BS, Covey AM, et al. Catheter- free survival after primary percutaneous stenting of malignant bile duct obstruction[J]. AJR Am J Roentgenol, 2011, 197: W514- W518.
[4] 马少军,翟仁友,赵 峰. 恶性梗阻性黄疸的介入治疗进展[J]. 中华介入放射学电子杂志, 2016, 4:119- 123.
[5] Cui FR, Liu W, Li WX. Comparison of ERCP and PTCD in the treatment of benign and malignant extrahepatic bile duct obstructive jaundice[J]. Int J Lab Med, 2018, 39: 342- 344.
[6] Duan F, Cui L, Bai Y, et al. Comparison of efficacy and compli- cations of endoscopic and percutaneous biliary drainage in malignant obstructive jaundice: a systematic review and meta- analysis[J]. Cancer Imaging, 2017, 17: 27.
[7] Zhu HD, Guo JH, Huang M, et al. Irradiation stents vs. conven- tional metal stents for unresectable malignant biliary obstruction: a multicenter trial[J]. J Hepatol, 2018, 68: 970- 977.
[8] Schlachterman A, Craft WW Jr, Hilgenfeldt E, et al. Current and future treatments for hepatocellular carcinoma[J]. World J Gastroenterol, 2015, 21: 8478- 8491.
[9] 韩成龙,马亦龙,欧盛秋,等. 125I粒子条联合胆道支架植入治疗恶性梗阻性黄疸22例疗效分析[J]. 介入放射学杂志, 2015, 24:141- 145.
[10] Martinez JM, Anene A, Bentley TG, et al. Cost effectiveness of metal stents in relieving obstructive jaundice in patients with pancreatic cancer[J]. J Gastrointest Cancer, 2017, 48: 58- 65.
[11] Ma J, Luo J, Gu J, et al. Malignant obstructive jaundice treated with intraluminal placement of Iodine- 125 seed strands and metal stents: an analysis of long- term outcomes and prognostic features[J]. Brachytherapy, 2018, 17: 689- 695.
[12] 蒋国军,赵 丹,代义红. 近距内放疗联合经皮胆道支架治疗肝门胆管癌对黄疸复发及生存期的影响[J]. 现代消化及介入诊疗,2018, 23:668- 671.
[13] 王剑宇,徐 浩,许 伟,等. 支架联合内或外125I粒子条治疗恶性梗阻性黄疸临床研究[J]. 介入放射学杂志, 2019, 28:874- 877.
[14] 李 健,王 松,于春鹏,等. 胆管支架联合125I粒子条植入治疗恶性梗阻性黄疸相关并发症临床分析[J]. 齐鲁医学杂志, 2017, 32:171- 173, 177.
[15] 常海洋,王永正,王武杰,等. 胆道支架置入术联合125I支架内照射治疗恶性梗阻性黄疸效果观察[J]. 山东医药, 2015, 55:46- 47.
[16] 潘洪涛,刘会春,费圣贤,等. 胆道支架联合125I粒子腔内照射治疗肝门胆管癌的临床疗效[J]. 中华放射学杂志, 2016, 50:393- 396.
[17] 李宗明,焦德超,韩新巍,等. 125I粒子双链放疗引流管在恶性阻塞性黄疸治疗中的初步应用[J]. 郑州大学学报(医学版), 2019, 54:646- 649.
[18] 郭金和,朱光宇,朱海东,等. 胆管内照射支架的研制及临床应用的初步结果[J]. 中华医学杂志, 2011, 91:2310- 2313.
[19] 周 广,肖恩华,尚全良,等. 胆道金属裸支架与125I粒子支架治疗恶性胆道梗阻的疗效对比:一项单中心前瞻性研究[J]. 介入放射学杂志, 2018, 27:467- 472.
[20] 谢长远,陈林军,张军宪,等. 胆道支架联合动脉化疗栓塞术治疗恶性胆道梗阻40例效果分析[J]. 中国乡村医药, 2015, 22:16- 17.
[21] 朱 超,刘会春,胡小四,等. 胆道双支架联合125I粒子腔内照射治疗恶性肝门部胆道梗阻的疗效分析[J]. 介入放射学杂志, 2020, 29:1100- 1104.
[22] 谢宗贵,张希全,李凡东,等. 胆道支架技术5年回顾(213例随访报告)[J]. 中华肝胆外科杂志, 2002, 8:595- 597.

相似文献/References:

[1]姚红响,陈根生,叶冠雄,等.胆道支架联合125I粒子条治疗恶性梗阻性黄疸[J].介入放射学杂志,2014,(10):893.
 YAO Hong xiang,CHEN Gen sheng,YE Guan xiong,et al.Biliary stenting combined with 125I seed implantation intracavitary irradiation for the treatment of malignant obstructive jaundice[J].journal interventional radiology,2014,(11):893.
[2]诸葛英,姚红响,曾 群.胆道支架联合125I粒子条治疗恶性梗阻性黄疸的护理[J].介入放射学杂志,2015,(05):449.
 ZHU Ge ying,YAO Hong xiang,ZENG Qun.Nursing care for patients with malignant obstructive jaundice receiving biliary stenting combined with linear 125I seeds strand implantation[J].journal interventional radiology,2015,(11):449.
[3]周传国,魏宝杰,王剑锋,等.双支架联合植入治疗恶性胆管梗阻合并胃流出道梗阻 [J].介入放射学杂志,2018,27(09):847.
 ZHOU Chuanguo,WEI Baojie,WANG Jianfeng,et al.Combined implantation of dual stents for the treatment of malignant biliary obstruction complicated by gastric outlet obstruction[J].journal interventional radiology,2018,27(11):847.
[4]胡天鹏,沈 婕,邵梦麟,等.18F-FDG PET/CT 相关参数对肺癌患者125I粒子植入术后短期疗效的预测价值[J].介入放射学杂志,2022,31(06):577.
 HU Tianpeng,SHEN Jie,SHAO Menglin,et al.The clinical value of the relevant parameters of pre-treatment 18F-FDG PET-CT in predicting the short-term efficacy of radioactive 125I seed implantation in patients with lung cancer[J].journal interventional radiology,2022,31(11):577.

备注/Memo

备注/Memo:
(收稿日期:2021- 08- 31)
(本文编辑:新 宇)
更新日期/Last Update: 2022-12-09