[1]周传国,魏宝杰,王剑锋,等.双支架联合植入治疗恶性胆管梗阻合并胃流出道梗阻 [J].介入放射学杂志,2018,27(09):847-852.
 ZHOU Chuanguo,WEI Baojie,WANG Jianfeng,et al.Combined implantation of dual stents for the treatment of malignant biliary obstruction complicated by gastric outlet obstruction[J].journal interventional radiology,2018,27(09):847-852.
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双支架联合植入治疗恶性胆管梗阻合并胃流出道梗阻 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年09期
页码:
847-852
栏目:
非血管介入
出版日期:
2018-09-25

文章信息/Info

Title:
Combined implantation of dual stents for the treatment of malignant biliary obstruction complicated by gastric outlet obstruction
作者:
周传国 魏宝杰 王剑锋 黄 强 高 堃
Author(s):
ZHOU Chuanguo WEI Baojie WANG Jianfeng HUANG Qiang GAO Kun
Department of Interventional Radiology, Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
关键词:
【关键词】 胆道支架 十二指肠支架 胆管梗阻 十二指肠梗阻
文献标志码:
A
摘要:
【摘要】 目的 评价经皮胆道支架植入联合十二指肠支架置入处理胆道及胃流出道恶性梗阻的临床价值。方法 回顾性分析28例恶性胆道梗阻合并胃十二指肠梗阻的晚期恶性肿瘤患者,行经皮胆道支架植入及经口十二指肠支架置入。观察手术成功率、胆道梗阻及胃十二指肠梗阻症状缓解情况、手术并发症、支架通畅时间及患者生存时间。结果 28例患者均成功实施经皮胆管支架植入和经口十二指肠支架置入术,手术成功率100%。术后30 d患者血清总胆红素由(219.9±102.6) μmol/L降至(46.2±21.4) μmol/L,直接胆红素由(181.4±21.4) μmol/L降至(36.8±18.6) μmol/L,谷胺酰转肽酶(585.8±533.2) U/L降至(298.9±223.4) U/L,碱性磷酸酶(682.3±394.6) U/L 降至(341.9±239.6) U/L,天冬氨酸转氨酶(225.8±141.3) U/L降至(48.5±25.6) U/L,丙氨酸转氨酶(198.6±120.8) U/L降至(53.9±29.2) U/L,均明显下降(P<0.01)。胃出口梗阻评分由术前(0.6±0.5)分升至术后(1.4±0.5)分,差异具有统计学意义(P<0.05)。无30 d内死亡病例。胆道支架中位通畅时间109.5 d(31~187 d)及十二指肠支架中位通畅时间95.0 d(13~169 d),患者中位生存时间134 d(45~245 d)。结论 经皮胆道支架植入术联合十二指肠支架置入术处理恶性胆管梗阻合并胃流出道梗阻,手术成功率高、并发症少,是安全有效的晚期肿瘤姑息性治疗方法,可以改善临床症状,提高患者生活质量。

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备注/Memo

备注/Memo:
(收稿日期:2017-11-14)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2018-09-11