[1]梅百强,杨希立,许兆延,等.急性冠状动脉综合征患者心外膜脂肪组织体积与冠状动脉斑块特征相关性研究[J].介入放射学杂志,2021,30(12):1215-1218.
 MEI Baiqiang,YANG Xili,XU Zhaoyan,et al.Correlation between epicardial adipose tissue volume and coronary plaque characteristics in patients with acute coronary syndrome[J].journal interventional radiology,2021,30(12):1215-1218.
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急性冠状动脉综合征患者心外膜脂肪组织体积与冠状动脉斑块特征相关性研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年12
页码:
1215-1218
栏目:
心脏介入
出版日期:
2021-12-25

文章信息/Info

Title:
Correlation between epicardial adipose tissue volume and coronary plaque characteristics in patients with acute coronary syndrome
作者:
梅百强 杨希立 许兆延 梁 茜 李 健 岑锦明 吴雪锋 游 伟 徐志锋
Author(s):
MEI Baiqiang YANG Xili XU Zhaoyan LIANG Qian LI Jian CEN Jinming WU Xuefeng YOU Wei XU Zhifeng.
Department of Cardiology, Affiliated Foshan Municipal First People’s Hospital, Sun Yat-sen University, Foshan, Guangdong Province 528010, China
关键词:
【关键词】 急性冠状动脉综合征 经皮冠状动脉介入治疗 心外膜脂肪组织 血管内超声
文献标志码:
A
摘要:
【摘要】 目的 通过iMap-血管内超声(IVUS)分析急性冠状动脉综合征(ACS)患者冠状动脉粥样硬化斑块成分,探讨心外膜脂肪组织体积(EATV)与冠状动脉斑块特征的相关性。 方法 连续筛选2018 年1月至 2020 年 1月在佛山市第一人民医院接受择期冠状动脉造影(CAG)或经皮冠状动脉支架植入术,并完成iMap-IVUS分析的ACS患者89 例。所有患者入院后均接受心脏CTA检查,测算EATV。根据EATV水平将患者分为高水平组(H组,≥86 cm3,n=47)和低水平组(L组,<86 cm3,n=42),分析比较两组患者CAG和iMap-IVUS影像学结果。 结果 H组患者高敏C反应蛋白(hs-CRP)、肌钙蛋白(Tn)I、肌酸激酶同工酶(CK-MB)、肌酐(Cr)、脂蛋白相关磷脂酶(Lp-PLA)2均高于L组(P<0.05);冠状动脉斑块含钙化成分明显少于L组(P=0.002),坏死核心明显多于L组(P=0.007),且薄纤维帽斑块(TCFA)发生率显著高于L组(P=0.002)。logistic回归分析发现,EATV(OR=2.465,95%CI=1.35~4.50,P=0.002)是TCFA的独立预测因子。结论 iMap-IVUS分析证实,ACS患者EATV升高与易损斑块有良好相关性,可作为预测TCFA的潜在标志物。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2020- 09- 27)
(本文编辑:边 佶)
更新日期/Last Update: 2021-12-20