[1]陈 峰,王 洁,甘解华,等.MR三维动脉自旋标记、双指数模型弥散加权成像评估急性前循环大血管闭塞患者再通后再灌注损伤风险[J].介入放射学杂志,2021,30(12):1210-1214.
 CHEN Feng,WANG Jie,GAN Jiehua,et al.Application of MR 3D-ASL and bi-exponential model DWI in evaluating the risk of reperfusion injury in patients with acute anterior circulation large vessel occlusion after vascular recanalization[J].journal interventional radiology,2021,30(12):1210-1214.
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MR三维动脉自旋标记、双指数模型弥散加权成像评估急性前循环大血管闭塞患者再通后再灌注损伤风险()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年12
页码:
1210-1214
栏目:
神经介入
出版日期:
2021-12-25

文章信息/Info

Title:
Application of MR 3D-ASL and bi-exponential model DWI in evaluating the risk of reperfusion injury in patients with acute anterior circulation large vessel occlusion after vascular recanalization
作者:
陈 峰 王 洁 甘解华 王高燕 卢苗青 赵嘉林 陈 勇
Author(s):
CHEN Feng WANG Jie GAN Jiehua WANG Gaoyan LU Miaoqing ZHAO Jialing CHEN Yong.
Department of Neurology, Ningbo Medical Center LI Huili Hospital, Ningbo, Zhejiang Province 315040, China
关键词:
【关键词】 三维动脉自旋标记 脑血流量 双指数模型弥散加权成像 动脉取栓术 再灌注损伤
文献标志码:
A
摘要:
【摘要】 目的 探讨MR三维动脉自旋标记(3D-ASL)、双指数模型弥散加权成像(DWI)对急性前循环大血管闭塞脑梗死患者血管再通治疗后再灌注损伤风险的评估作用。方法 回顾性分析2018年6月至2020年6月在宁波市医疗中心李惠利医院接受取栓治疗的36例脑梗死患者。根据术后临床和功能MRI表现,将患者分为高灌注组和无高灌注组。比较不同灌注患者临床特征、脑血流量(CBF)、表观弥散系数(ADC)等参数差异。结果 36例患者中无高灌注组22例(61.1%),高灌注组14例(38.9%)。单因素分析显示,无高灌注组患者年龄、术前美国国立卫生研究院卒中量表(NIHSS)评分,术后绝对CBF、相对CBF(rCBF)、ADCfast、ADCslow均低于高灌注组(P<0.05)。Spearman相关性分析显示,CBF与ADCfast呈显著正相关(r=0.697,P<0.01)。二元logistic回归分析显示ADCfast是预测患者术后高灌注的独立危险因素(P<0.05),受试者工作特征曲线(ROC)分析显示最佳阈值为51.2×10-4 mm2/s。结论 MR 3D-ASL、双指数DWI技术可较好地评估急性脑梗死患者血管再通术后再灌注损伤风险。

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备注/Memo

备注/Memo:
(收稿日期:2020- 12- 01)
(本文编辑:边 佶)
更新日期/Last Update: 2021-12-20