[1]侯立泳,高兴强,王 永,等.经皮微波消融与胸腔镜肺叶切除术治疗Ⅰ期非小细胞肺癌的疗效[J].介入放射学杂志,2019,28(09):851-854.
 HOU Liyong,GAO Xingqiang,WANG Yong,et al.CT- guided percutaneous microwave ablation versus thoracoscopic lobectomy for the treatment of stage I NSCLC: analysis of curative effect[J].journal interventional radiology,2019,28(09):851-854.
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经皮微波消融与胸腔镜肺叶切除术治疗Ⅰ期非小细胞肺癌的疗效()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年09期
页码:
851-854
栏目:
非血管介入
出版日期:
2019-09-25

文章信息/Info

Title:
CT- guided percutaneous microwave ablation versus thoracoscopic lobectomy for the treatment of stage I NSCLC: analysis of curative effect
作者:
侯立泳 高兴强 王 永 于永超 念丁芳
Author(s):
HOU Liyong GAO Xingqiang WANG Yong YU Yongchao NIAN Dingfang.
Department of Interventional Radiology, Qingdao Haici Medical Group, Qingdao, Shandong Province 266033, China
关键词:
【关键词】 微波消融术 胸腔镜 非小细胞肺癌 疗效 预后
文献标志码:
A
摘要:
【摘要】 目的 探究CT引导下经皮微波消融(MWA)与胸腔镜肺叶切除术治疗Ⅰ期非小细胞肺癌(NSCLC)的疗效及预后。方法 选取2015年3月至2017年2月139例NSCLC患者作为研究对象。根据治疗方案将139例NSCLC患者分为两组,MWA组(n=65)和胸腔镜组(n=74)。比较两组患者手术疗效、术后并发症发生情况、手术相关指标及生存情况。结果 两组患者肿瘤清除率比较,差异无统计学意义(P>0.05)。两组患者治疗期间均未出现死亡病例。两组患者并发症发生率比较,胸腔镜组和MWA组分别为20/74和14/65,差异无统计学意义。胸腔镜组肿瘤100%切除,MWA组肿瘤完全消融,两组差异无统计学意义(P>0.05)。MWA组患者手术时间、术后住院时间及住院费用均低于胸腔镜组,差异有统计学意义(P<0.05)。MWA组患者1、2年总生存率(OS)和无瘤生存率(DFS)与胸腔镜组比较,差异均无统计学意义(P>0.05)。MWA组患者平均总生存时间及平均DFS与胸腔镜组比较,差异无统计学意义(P>0.05)。结论 MWA与胸腔镜肺叶切除术治疗Ⅰ期NSCLC疗效相当,且较为安全。MWA治疗Ⅰ期NSCLC的手术时间、术后住院时间及费用均低于胸腔镜肺叶切除术。

参考文献/References:

[1] Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012[J]. CA Cancer J Clin, 2015, 65: 87-108.
[2] Cheng JM, Li CY, Wang LW, et al. Precise localization of small pulmonary nodules using Pre-VATS with Xper-CT in combination with real-time fluoroscopy-guided coil: report of 15 patients[J]. J Intervent Med, 2018, 1: 102-105.
[3] 胡 兰, 郭 庆, 文 丹, 等. CT引导下经皮肺穿刺活检术诊断肺癌准确性的回顾性分析[J].介入放射学杂志, 2018, 27:274-277.
[4] Little AG, Gay EG, Gaspar LE, et al. National survey of non-small cell lung cancer in the United States: epidemiology, pathology and patterns of care[J]. Lung Cancer, 2007, 57: 253-260.
[5] 黄大钡, 李晓群, 张 健, 等. C臂CT在肺小结节胸腔镜切除术前定位中的应用[J]. 介入放射学杂志, 2017, 26: 843-846.
[6] Wei Z, Ye X, Yang X, et al. Microwave ablation combined with EGFR- TKIs versus only EGFR- TKIs in advanced NSCLC patients with EGFR- sensitive mutations[J]. Oncotarget, 2017, 8: 56714-56725.
[7] Sun YH, Song PY, Guo Y, et al. Effects of microwave ablation or its combination with whole- body chemotherapy on serum vascular endothelial growth factor levels in patients with stage IIIB/IV NSCLC[J]. Genet Mol Res, 2015, 14: 10015-10025.
[8] Acksteiner C, Steinke K. Percutaneous microwave ablation for early-stage non-small cell lung cancer(NSCLC) in the elderly: a promising outlook[J]. J Med Imaging Radiat Oncol, 2015, 59: 82-90.
[9] Steinke K, Liu H. Minimally invasive techniques for medically inoperable stage I non- small cell lung cancer(NSCLC): image-guided microwave ablation, a promising therapy option[J]. J Med Imaging Radiat Oncol, 2014, 58: 79-80.
[10] Wei Z, Ye X, Yang X, et al. Advanced non small cell lung cancer: response to microwave ablation and EGFR Status[J]. Eur Radiol, 2017, 27: 1685-1694.
[11] Wu Z, Wang Q, Wu C, et al. Three- port single- intercostal versus multiple-intercostal thoracoscopic lobectomy for the treatment of lung cancer: a propensity- matched analysis[J]. BMC Cancer, 2019, 19: 8.
[12] Zhang XF, Li DY, Wu JX, et al. Comparison of deep or moderate neuromuscular blockade for thoracoscopic lobectomy: a randomized controlled trial[J]. BMC Anesthesiol, 2018, 18: 195.
[13] Zhang Z, Huang Q, Liao Y, et al. Application of the "continuous suture dividing and equal suture tightening" method in video-assisted thoracoscopic surgery sleeve lobectomy[J]. J Thorac Dis, 2018, 10: 5199- 5207.
[14] Liu X, Chen X, Shen Y, et al. Learning curve for uniportal video-assisted thoracoscopic surgery lobectomy-results from 120 consecutive patients[J]. J Thorac Dis, 2018, 10: 5100-5107.
[15] Yao W, Lu M, Fan W, et al. Comparison between microwave ablation and lobectomy for stage I non- small cell lung cancer: a propensity score analysis[J]. Int J Hyperthermia, 2018, 34: 1329-1336.

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备注/Memo

备注/Memo:
(收稿日期:2019-01-22)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2019-09-24