[1]吴 萍,秦 敏,李 尊,等.微波消融治疗T1N0M0乳头状甲状腺癌伴包膜侵犯的初步研究[J].介入放射学杂志,2023,32(10):975-979.
 WU Ping,QIN Min,LI Zun,et al.Preliminary study of microwave ablation for T1N0M0 stage papillary thyroid carcinoma with concomitant capsule invasion[J].journal interventional radiology,2023,32(10):975-979.
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微波消融治疗T1N0M0乳头状甲状腺癌伴包膜侵犯的初步研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年10
页码:
975-979
栏目:
非血管介入
出版日期:
2023-10-31

文章信息/Info

Title:
Preliminary study of microwave ablation for T1N0M0 stage papillary thyroid carcinoma with concomitant capsule invasion
作者:
吴 萍 秦 敏 李 尊 钱 丰
Author(s):
WU Ping QIN Min LI Zun QIAN Feng.
Department of Ultrasound, Affiliated Wujin Hospital of Jiangsu University(Wujin Clinical College of Xuzhou Medical University), Changzhou, Jiangsu Province 213000, China
关键词:
【关键词】 超声造影 微波消融 乳头状甲状腺癌 包膜侵犯 甲状腺激素 并发症
文献标志码:
A
摘要:
【摘要】 目的 探讨超声引导微波消融治疗T1N0M0乳头状甲状腺癌(PTC)伴包膜侵犯的可行性和有效性。方法 选择2017年3月至2021年9月江苏大学附属武进医院和苏州大学附属第三医院病理确诊PTC伴包膜侵犯(T1N0M0)患者共86例,采用超声引导下延长和多点微波消融以及液体隔离策略治疗。并采用超声造影测量消融术前1 d和消融后1、3、6、12个月的肿瘤最大直径和体积变化,检测消融前和消融后1、3、6、12个月血清甲状腺激素水平。记录随访12个月肿瘤进展率(包括局部复发、新发病灶和淋巴结转移)和并发症。结果 所有患者均成功完成微波消融术和术后12个月的临床随访,消融总时间50~185s,平均(135±60)s,水分离体积30~80 mL,平均(52±16) mL。术后1个月肿瘤最大直径和体积较术前显著增加,随后逐渐缩小(P<0.05)。63例(73.3%,63/86)肿瘤完全消失,未检测到局部复发。消融前后各时间点促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)和甲状腺素(FT4)水平均无显著变化,均在正常参考范围(P>0.05)。所有患者术后均未常规应用甲状腺替代药物。7例(8.1%,7/86)出现肿瘤进展,其中6例为新发病灶、1例为淋巴结转移,经二次消融后肿瘤完全消失。轻度嗓音改变(5.8%,5/86)是唯一主要并发症,术后6个月内缓解。结论 超声引导微波消融治疗T1N0M0期 PTC伴包膜侵犯具有较好的安全性和临床疗效,值得推广应用。

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备注/Memo

备注/Memo:
(收稿日期:2022- 10- 18)
(本文编辑:茹 实)
更新日期/Last Update: 2023-10-31