[1]刘 晟,周平盛,钱国军.经皮微波消融治疗近肠道肝细胞癌74例疗效分析[J].介入放射学杂志,2016,(05):404-407.
　LIU Sheng,ZHOU Ping- sheng,QIAN Guo- jun.Percutaneous microwave ablation for the treatment of hepatocellular carcinoma adjacent to the intestinal tract： analysis of curative effect in 74 patients[J].journal interventional radiology,2016,(05):404-407.
点击复制

经皮微波消融治疗近肠道肝细胞癌74例疗效分析 ()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2016年05期
页码:
404-407
栏目:
非血管介入
出版日期:
2016-05-25

文章信息/Info

Title:
Percutaneous microwave ablation for the treatment of hepatocellular carcinoma adjacent to the intestinal tract： analysis of curative effect in 74 patients
作者:
刘 晟;  周平盛;  钱国军
Author(s):
LIU Sheng;  ZHOU Ping- sheng;  QIAN Guo- jun
Department of Minimally Invasive Surgery， Eastern Hepatobiliary Surgery Hospital， Shanghai 200438， China
关键词:
【关键词】 肝细胞癌;  微波消融;  长期预后;  早期
文献标志码:
A
摘要:
【摘要】 目的 评价超声引导下经皮微波消融（MWA）对近肠道部位肝细胞癌的安全性、局部疗效、长期预后，并分析预后影响因素。方法 回顾性分析2008年3月至2010年7月接受超声引导下MWA治疗的74例初发近肠道肝细胞癌患者的临床资料。观察完全消融率、术后并发症、局部肿瘤进展，计算术后长期生存率并分析预后影响因素。结果 90枚肿瘤中的84枚首次达到完全消融，完全消融93.3%；局部肿瘤进展10.8%；1、3、5 年总生存率和无瘤生存率分别为97.3%、74.3%、45.9%和87.7%、51.4%、31.1%；HCV是影响无瘤生存率的独立危险因素，多发肿瘤是影响总生存率的独立危险因素。结论 经皮MWA是治疗近肠道肝细胞癌安全、有效的方式，术前肠道准备、穿刺采用平行肠道进针方式、术后禁食水可降低肠道损伤风险。

参考文献/References:

［1］ Itoh S, Ikeda Y, Kawanaka H, et al. Efficacy of surgical microwave therapy in patients with unresectable hepatocellular carcinoma［J］. Ann Surg Oncol, 2011, 18: 3650- 3656.
［2］ Bruix J, Sherman M. Management of hepatocellular carcinoma: an update［J］. Hepatology, 2011, 53: 1020- 1022.
［3］ Nishikawa H, Inuzuka T, Takeda H, et al. Percutaneous radiofre- quency ablation therapy for hepatocellular carcinoma: a proposed new grading system for the ablative margin and prediction of local tumor progression and its validation［J］. J Gastroenterol, 2011, 46: 1418- 1426.
［4］ 经 翔， 丁建民， 王彦冬， 等． 射频消融和微波消融治疗肝癌的比较［J］． 介入放射学杂志， 2014， 23： 306- 310．
［5］ Nakazawa T, Kokubu S, Shibuya A, et al. Radiofrequency ablation of hepatocellular carcinoma: correlation between local tumor progression after ablation and ablative margin［J］. AJR Am J Roent- genol, 2007, 188: 480- 488.
［6］ Qian GJ, Wang N, Shen Q, et al. Efficacy of microwave versus radiofrequency ablation for treatment of small hepatocellular carcinoma: experimental and clinical studies［J］. Eur Radiol, 2012, 22: 1983- 1990.
［7］ Shi J, Sun Q, Wang Y, et al. Comparison of microwave ablation and surgical resection for treatment of hepatocellular carcinomas conforming to milan criteria［J］. J Gastroenterol Hepatol, 2014, 29: 1500- 1507.
［8］ Lü MD, Xu HX, Xie XY, et al. Percutaneous microwave and radiofrequency ablation for hepatocellular carcinoma: a retros- pective comparative study［J］. J Gastroenterol, 2005, 40: 1054- 1060.
［9］ 王 能， 钱国军， 沈 强， 等． 经皮肝穿刺射频治疗肝恶性肿瘤的严重并发症分析［J］． 中华肝胆外科杂志， 2011， 17： 186- 188．
［10］ Zhang M, Liang P, Cheng ZG, et al. Efficacy and safety of artificial ascites in assisting percutaneous microwave ablation of hepatic tumours adjacent to the gastrointestinal tract［J］. Int J Hyperthermia, 2014, 30: 134- 141.
［11］ Ding J, Jing X, Liu J, et al. Comparison of two different thermal techniques for the treatment of hepatocellular carcinoma［J］. Eur J Radiol, 2013, 82: 1379- 1384.
［12］ 许 贇， 王 能， 沈 强， 等． 经皮热消融治疗极早期肝癌的疗效及预后因素分析［J］． 中国普通外科杂志， 2015， 24： 945- 951．
［13］ 李晓峰， 钱国军， 张 磊， 等．微波高功率条件下消融原发性肝癌的初步研究［J］． 介入放射学杂志， 2011， 20： 974- 978．

相似文献/References:

[1]姚雪松,李 槐.不可手术切除的肝细胞癌的疗效评价标准——改良ＲＥＣＩＳＴ标准更可靠[J].介入放射学杂志,2012,(03):177.
　. Ｔｈｅｒａｐｅｕｔｉｃ ｅｖａｌｕａｔｉｏｎ ｃｒｉｔｅｒｉｏｎ ｏｆ ｉｎｏｐｅｒａｂｌｅ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａｓ： ｍｏｄｉｆｉｅｄ ＲＥＣＩＳＴ ａｓ ａ ｍｏｒｅ ｒｅｌｉａｂｌｅ ｓｔａｎｄａｒｄ[J].journal interventional radiology,2012,(05):177.
[2]梁茂全,苏洪英. 肝癌化疗栓塞前后甲胎蛋白变化模式的临床意义[J].介入放射学杂志,2012,(04):333.
　.Ｔｈｅ ｔｒａｎｓｆｏｒｍａｔｉｏｎ ｐａｔｔｅｒｎ ｏｆ ｓｅｒｕｍ аｆｅｔｏｐｒｏｔｅｉｎ ａｆｔｅｒ ｔｒａｎｓｃａｔｈｅｔｅｒ ａｒｔｅｒｉａｌ ｃｈｅｍｏｅｍｂｏｌｉｚａｔｉｏｎ ｉｎ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａ： ｉｔｓ ｃｌｉｎｉｃａｌ ｓｉｇｎｉｆｉｃａｎｃｅ [J].journal interventional radiology,2012,(05):333.
[3]孙 磊,施海彬,刘 圣,等.肝细胞癌肝动脉门静脉分流形成的相关因素分析[J].介入放射学杂志,2012,(03):206.
　,,et al.Ｔｈｅ ｆａｃｔｏｒｓ ｒｅｌａｔｅｄ ｔｏ ｔｈｅ ｆｏｒｍａｔｉｏｎ ｏｆ ａｒｔｅｒｉｏｐｏｒｔａｌ ｓｈｕｎｔｉｎｇ ｉｎ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａｓ [J].journal interventional radiology,2012,(05):206.
[4]沈海洋,刘瑞宝,刘 岩,等. 肝右叶前、后段原发性肝癌TACE后VEGF及CD34的表达水平 ；[J].介入放射学杂志,2012,(06):469.
　SHEN Hai- yang,LIU Rui- bao,LIU Yan,et al. The expression levels of vascular endothelial growth factor and CD34 in residual cancerous tissues of primary hepatocellular carcinoma located at anterior and posterior segments of right lobe liver after TACE[J].journal interventional radiology,2012,(05):469.
[5]彭辽河,胡晓燕,李 杰,等. 18F-FDG PET/CT显像在肝细胞癌TACE术后残留或复发病灶检出中的应用价值[J].介入放射学杂志,2012,(08):636.
　PENG Liao- he,HU Xiao- yan,LI Jie,et al. Clinical application of 18F- FDG PET/CT imaging in detecting residual lesions or recurrence foci of hepatocellular carcinoma after TACE treatment[J].journal interventional radiology,2012,(05):636.
[6]陆小华,朱小庆,茅国新.肝细胞癌相关单核苷酸多态性的研究进展[J].介入放射学杂志,2013,(06):520.
　LU Xiao? hua,ZHU Xiao? qing,MAO Guo? xin.. Hepatocellular carcinoma?蛳 related single nucleotide polymorphisms： recent advances in research[J].journal interventional radiology,2013,(05):520.
[7]陈奇峰,贾振宇,杨正强,等.肝动脉化疗栓塞联合微波消融与单独肝动脉化疗栓塞治疗大肝癌疗效meta分析[J].介入放射学杂志,2017,(03):225.
　CHEN Qifeng,JIA Zhenyu,YANG Zhengqiang,et al.TACE combined with MWA versus simple TACE for the treatment of large hepatic cancers： a meta- analysis of curative effect[J].journal interventional radiology,2017,(05):225.
[8]杨国威,张 巍,钱 晟,等.热损伤对肝细胞肝癌细胞增殖及侵袭转移特性影响的实验研究 [J].介入放射学杂志,2017,(05):436.
　YANG Guowei,ZHANG Wei,QIAN Sheng,et al.The effect of thermal damage on the cell proliferation and invasive metastasis of HCC： an experimental study in vitro[J].journal interventional radiology,2017,(05):436.
[9]李 鑫,梁 萍,于晓玲,等.经皮微波消融肾细胞癌疗效的超声造影评价[J].介入放射学杂志,2014,(08):688.
　LI Xin,LIANG Ping,YU Xiao ling,et al.Percutaneous microwave ablation for renal cell carcinoma： evaluation of therapeutic effect with contrast enhanced ultrasound[J].journal interventional radiology,2014,(05):688.
[10]姚雪松,闫 东,曾辉英,等.TACE联合索拉非尼治疗不能手术切除肝细胞癌介入治疗间隔时间的分析[J].介入放射学杂志,2014,(09):769.
　YAO Xue song,YAN Dong,ZENG Hui ying,et al.TACE combined with sorafenib for inoperable hepatocellular carcinoma： analysis of treatment interval[J].journal interventional radiology,2014,(05):769.
[11]李晓峰,钱国军,张 磊,等. 微波高功率条件下消融原发性肝癌的初步研究[J].介入放射学杂志,2011,(12):974.
　LI Xiao-feng,QIAN Guo-jun,ZHANG Lei,et al.Microwave ablation with high output power for the treatment of hepatocellular carcinoma: a preliminary study[J].journal interventional radiology,2011,(05):974.
[12]王晓维,付守忠,戴 锋,等.肝动脉栓塞化疗联合射频消融与联合微波消融治疗原发性肝癌的疗效和安全性比较 [J].介入放射学杂志,2016,(08):673.
　WANG Xiao-wei,FU Shou-zhong,DAI Feng,et al.The curative effect and safety in treating primary hepatocellular carcinoma: comparison between TACE plus radiofrequency ablation and TACE plus microwave ablation [J].journal interventional radiology,2016,(05):673.
[13]周平盛,王延明,钱国军,等.微波消融治疗单发5 cm以下肝细胞肝癌预后及其影响因素分析 [J].介入放射学杂志,2017,(08):712.
　ZHOU Pingsheng,WANG Yanming,QIAN Guojun,et al.Microwave ablation for solitary hepatocellular carcinoma sized less than 5 cm： analysis of prognosis and its influence factors[J].journal interventional radiology,2017,(05):712.
[14]周平盛,刘 晟,王 能,等.超声引导下微波消融治疗肝细胞癌术后肿瘤复发及其危险因素分析[J].介入放射学杂志,2022,31(12):1174.
　ZHOU Pingsheng,LIU Sheng,WANG Neng,et al.Analysis of tumor recurrence and its risk factors after ultrasound-guided microwave ablation for hepatocellular carcinoma[J].journal interventional radiology,2022,31(05):1174.

备注/Memo

备注/Memo:
（收稿日期：２０１6-０1-31）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2016-05-16