[1]唐 田,古善智,李国文,等.经皮肝穿刺胆道引流联合CT引导下微波消融治疗肝门区胆管癌的疗效分析[J].介入放射学杂志,2015,(09):811-814.
　TANG Tian,GU Shan- zhi,LI Guo- wen,et al.PTCD combined with CT- guided microwave ablation for hepatic hilar cholangiocarcinoma： analysis of therapeutic efficacy[J].journal interventional radiology,2015,(09):811-814.
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经皮肝穿刺胆道引流联合CT引导下微波消融治疗肝门区胆管癌的疗效分析 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年09期
页码:
811-814
栏目:
临床研究
出版日期:
2015-09-25

文章信息/Info

Title:
PTCD combined with CT- guided microwave ablation for hepatic hilar cholangiocarcinoma： analysis of therapeutic efficacy
作者:
唐 田;  古善智;  李国文;  黄满平;  黄 斌;  熊正平
Author(s):
TANG Tian;  GU Shan- zhi;  LI Guo- wen;  HUANG Man- ping;  HUANG Bin;  XIONG Zheng- ping
Department of Interventional Radiology， Hunan Provincial Cancer Hospital & Affiliated Cancer Hospital of Xiangya School of Medicine， Central South University， Changsha， Hunan Province 410013， China
关键词:
【关键词】 肝门区胆管癌;  微波消融;  经皮肝穿刺胆道引流;  介入放射学;  CT引导
文献标志码:
A
摘要:
【摘要】 目的 探讨经皮肝穿刺胆道引流联合CT引导下微波消融（MWA）治疗肝门区胆管癌的应用价值。方法 回顾性分析自2012年12月至2014年8月29例不可手术切除的Ⅲ、Ⅳ型肝门区胆管癌伴梗阻性黄疸患者，经病理证实胆管腺癌，其中19例行胆道内外引流术，4例行胆道外引流术，6例行左右两侧胆管引流术，待肝功能改善后，行肝门区肿块MWA治疗，29例患者完成46次消融治疗，每例平均1.5次，术后4～8周复查肝功能、增强CT或者MR，采用mRECIST标准评价肿瘤治疗疗效，观察患者的胆红素变化，随访其进展及生存时间。结果 术后1个月完全缓解（CR）15例（15/29，51.7%）、部分缓解（PR）17例（17/29，58.6%），整体有效率82%（CR+PR），1例患者术后出现肝内转移，1例出现肺转移，29例患者术后胆红素均明显下降，6个月、1年、2年生存率分别为68.9%（20/29），31.0%（9/29），6.8%（2/29），中位生存期（MST）8.9个月，总生存期（OS）11.7个月。结论 经皮肝穿刺胆道引流联合CT引导下MWA治疗肝门区胆管癌是微创、安全、有效的治疗方法。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：２０１4-11-22）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2015-09-23