[1]刘 丽,钟嘉明,陈晓霞,等.肝动脉化疗栓塞术联合自体DC CIK细胞治疗BCLC C期肝癌的随机对照研究[J].介入放射学杂志,2015,(05):434-438.
 LIU Li,ZHONG Jia ming,CHEN Xiao xia,et al.Transarterial chemoembolization combined with autologous DC CIK cells for the treatment of hepatocellular carcinoma of BCLC C stage: a randomized controlled study[J].journal interventional radiology,2015,(05):434-438.
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肝动脉化疗栓塞术联合自体DC CIK细胞治疗BCLC C期肝癌的随机对照研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年05期
页码:
434-438
栏目:
临床研究
出版日期:
2015-05-25

文章信息/Info

Title:
Transarterial chemoembolization combined with autologous DC CIK cells for the treatment of hepatocellular carcinoma of BCLC C stage: a randomized controlled study
作者:
刘 丽 钟嘉明 陈晓霞 丁 宁 钱其军 曲增强
Author(s):
LIU Li' target="_blank" rel="external">"serif"; LINE-HEIGHT: 200%">LIU Li ZHONG Jia ming CHEN Xiao xia DING Ning QIAN Qi jun QU Zeng qiang
Department of Interventional Radiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China
关键词:
【关键词】 肝细胞癌 肝动脉化疗栓塞 DC CIK 免疫功能 T淋巴细胞亚群
文献标志码:
A
摘要:
【摘要】 目的 探讨肝动脉化疗栓塞(TACE)联合DC CIK细胞治疗BCLC C期肝细胞癌的疗效。方法 60例BCLC C期HCC患者随机分为治疗组与对照组,治疗组患者采用TACE联合DC CIK治疗,对照组患者只行TACE治疗,比较两组患者的免疫功能、半年和1年生存率。结果 治疗组全血T细胞亚群CD3+CD8+明显升高,CD3+CD4+明显下降,较治疗前差异有统计学意义(P<0.05)。两组半年生存率分别为67.9%、48.1%(P<0.05),一年生存率分别为53.6%、 29.6%(P<0.05)。结论 TACE联合DC CIK细胞联合治疗比单纯TACE治疗效果更好,是BCLC C期肝细胞癌的一种有效的治疗方法。

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备注/Memo

备注/Memo:
(收稿日期:2014-11-04)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2015-05-19