[1]李海伟,刘 静,李 森.125I粒子植入与伽玛刀治疗门脉癌栓的疗效对比[J].介入放射学杂志,2014,(08):702-705.
 LI Hai wei,LIU Jing,LI Sen..125Iodine seed implantation and gamma knife for the treatment of portal vein tumor thrombosis in hepatocellular carcinoma: comparison of therapeutic efficacy[J].journal interventional radiology,2014,(08):702-705.
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125I粒子植入与伽玛刀治疗门脉癌栓的疗效对比 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年08期
页码:
702-705
栏目:
非血管介入
出版日期:
2014-08-25

文章信息/Info

Title:
125Iodine seed implantation and gamma knife for the treatment of portal vein tumor thrombosis in hepatocellular carcinoma: comparison of therapeutic efficacy
作者:
李海伟 刘 静 李 森
Author(s):
LI Hai wei LIU Jing LI Sen.
Department of Interventional Radiology, Liaoning Provincial Cancer Hospital, Shenyang, Liaoning Province110042, China
关键词:
【关键词】 原发性肝癌 门静脉癌栓 伽玛刀 125I放射粒子植入
文献标志码:
A
摘要:
【摘要】 目的 比较125I放射粒子植入与伽玛刀治疗门静脉癌栓的疗效,探讨其临床应用价值。方法 2009年1月—2013年5月的原发性肝癌合并门静脉癌栓的60例患者分为两组,30例采用伽玛刀治疗,计划设计3 ~ 10个靶点,单次剂量3 ~ 6 Gy, 2 ~ 5 次/周,照射总量30 ~ 50 Gy。治疗计划中50% ~ 70%等剂量曲线包绕计划靶区(PTV)。另30例采用125I放射粒子植入治疗,观察治疗后门静脉癌栓的变化。结果 治疗后3个月,伽玛刀组癌栓完全消失(CR)0例,部分缓解(PR)8例(26.6%),无变化(SD)17例(56.7%),进展(PD)5例(16.7%);粒子植入组完全消失3例(10.0%),部分缓解19例(63.4%),无变化(SD)7例(23.3%),进展(PD)1例(3.3%)。2组比较差异有统计学意义(P < 0.05)。2组在腹水及肝功能改善方面差异无统计学意义(P > 0.05)。结论 125I放射粒子植入治疗门静脉癌栓近期疗效优于伽玛刀,远期疗效有待于进一步研究。 

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2013-12-08)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-08-22