[1]张晓前,郭 鹏,党之俊,等.金龙胶囊联合介入疗法治疗原发性肝癌临床观察[J].介入放射学杂志,2012,(03):249-251.
 ,,et al.Kinglong capsules combined with interventional therapy for hepatocellular carcinomas: clinical observation [J].journal interventional radiology,2012,(03):249-251.
点击复制

金龙胶囊联合介入疗法治疗原发性肝癌临床观察 ()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年03期
页码:
249-251
栏目:
临床研究
出版日期:
2012-03-28

文章信息/Info

Title:
Kinglong capsules combined with interventional therapy for hepatocellular carcinomas: clinical observation  
作者:
 张晓前 郭 鹏 党之俊 温树伟
Author(s):
 ZHANG Xiaoqian GUO Peng DANG Zhijun WEN Shuwei.  
  Department of Interventional Radiology, Shanxi Provincial Tumor Hospital, Taiyuan, Shanxi Province 030013, China
关键词:
 【关键词】 原发性肝癌 介入治疗 金龙胶囊
文献标志码:
A
摘要:
 【摘要】 目的 观察分别接受金龙胶囊联合肝动脉介入治疗和单纯介入疗法的原发性肝细胞癌患者的预后,比较两种方法的疗效。方法 对2001年1月至2006年12月山西省肿瘤医院收治的151例肝癌患者进行随访和分析,其中74例进行介入疗法的同时加服中药金龙胶囊,77例进行单纯介入疗法,记录治疗前后生物学标志改变,并在各组指标均衡可比的基础上,采用KappaMenire方法比较两种治疗方法的平均生存率,中位生存期的比较采用LogRank检验,疗效、不良反应等资料的比较采用卡方检验。结果 151例肝癌患者中位生存14个月。治疗前两组资料各指标之间差别无统计学意义(P均 >0.05),组间均具可比性。金龙胶囊联合介入治疗组的中位生存期为18.5个月,单纯介入疗法组的中位生存期为11.7个月,经LogRank检验,两组中位生存期差别具有统计学意义(χ2 = 13.32,P < 0.01)。两组病例疗效、生活质量变化(KPS 评分)以及不良反应等的比较,差别也均有统计学意义(P均< 0.05)。结论 金龙胶囊联合介入治疗效果优于单纯介入化疗。

参考文献/References:

[1]   Parkin DM, Bray F, Ferlay PP. Global Cancer statistics 2002[J]. CA Cancer J Clin, 2005, 55: 74  108.
[2]   赵剑波, 李彦豪, 陈   勇, 等. 原发性肝癌患者介入治疗后生命质量得分的变化分析[J]. 临床放射学杂志, 2002, 21: 550  552.
[3]   张百红. 肝癌化疗的研究进展[J]. 国外医学: 肿瘤学分册, 2003, 30: 384  387.
[4]   Guan YS, Liu Y. Interventional treatments for hepatocellular carcinoma[J]. Hepatobiliary Pancreat Dis Int, 2006, 5: 495  500.
[5]   Lu W, Li YH, Yu ZJ, et al. A comparative study of damage to liver function after TACE with use of lowdose versus conventionaldose of anticancer drugs in hepatocellular carcinoma[J]. Hepatogastroenterology, 2007, 54: 1499  1502.
[6]   中国抗癌协会肝癌专业委员会. 原发性肝癌的临床诊断与分期标准[J]. 现代实用医学, 2002, 16: 213.
[7]   Greene FL, Page DL, Fleming ID, et al. Liver including intrahepatic bile ducts[M]//American Joint Committee on cancer staging manual. 6th ed. New York: Springer  2002: 131  144.
[8]   孙   燕, 周际昌. 临床肿瘤内科手册[M]. 4版. 北京: 人民卫生出版社, 2003: 102  107.
[9]   刘士辰. 肝细胞癌化疗及介入治疗现状[J]. 国外医学: 肿瘤学分册, 2003, 30: 40  43.
[10] 石怀芝. 金龙胶囊配合辨证施治治疗原发性肝癌30例临床观察[J]. 北京中医, 2000, 19: 30  32.

相似文献/References:

[1].Spontaneous regression of a giant basilar artery aneurysm in a young adult after surgical injury :case report and literature review[J].介入放射学杂志,2007,(10):718.
 ZHANG He,LI Ming-hua,WANG Chun,et al.Spontaneous regression of a giant basilar artery aneurysm in a young adult after surgical injury :case report and literature review[J].journal interventional radiology,2007,(03):718.
[2]李统怀,郑红枫. 子宫动脉栓塞治疗子宫瘢痕妊娠11例[J].介入放射学杂志,2011,(11):898.
 LI Tong-huai,ZHENG Hong-feng..Clinical application of uterine artery embolization in treating uterine scar pregnancy[J].journal interventional radiology,2011,(03):898.
[3]吕维富,张爱武,周春泽,等. 子宫动脉的三维DSA表现及其最佳显示体位探讨[J].介入放射学杂志,2011,(11):853.
 LV Wei-fu,ZHANG Ai-wu,ZHOU Chun-ze,et al.3D-DSA findings of uterine artery and its optimal projection position[J].journal interventional radiology,2011,(03):853.
[4]张 靖,周少毅,陈昆山,等.经导管动脉硬化栓塞联合注射硬化治疗婴儿颌面部巨大高流量血管瘤[J].介入放射学杂志,2011,(11):848.
 ZHANG Jing,ZHOU Shao-yi,CHEN Kun-shan,et al.Transcatheter arterial sclerosing embolization with injection sclerotherapy for the treatment of huge and high-flow maxillofacial hemangiomas in infants[J].journal interventional radiology,2011,(03):848.
[5]谢小西,吕银祥,章宏欣,等. 肝动脉化疗栓塞、射频消融联合125Ⅰ粒子植入 治疗原发性肝癌的临床应用[J].介入放射学杂志,2011,(11):863.
 XIE Xiao-xi,LV Yin-xiang,ZHANG Hong-xin,et al.The clinical application of TACE together with RFA and 125Ⅰ seed implantation in treating hepatocellular carcinoma[J].journal interventional radiology,2011,(03):863.
[6]王铭义,王 峰. 脑灌注成像在颈动脉狭窄介入治疗中的应用[J].介入放射学杂志,2011,(11):915.
 WANG Ming-yi,WANG Feng..Application of brain perfusion imaging in interventional treatment of carotid artery stenosis[J].journal interventional radiology,2011,(03):915.
[7]杜 猛,张锦生. 介入治疗急性深静脉血栓的临床观察[J].介入放射学杂志,2011,(11):858.
 DU Meng,ZHANG Jing-sheng..Interventional therapy for acute deep venous thrombosis: a clinical observation[J].journal interventional radiology,2011,(03):858.
[8]孟庆娜,李国庆,白晓冬. 急性心肌梗死介入治疗术中恶心呕吐的护理[J].介入放射学杂志,2011,(11):913.
 MENG Qing-na,LI Guo-qing,BAI Xiao-dong..The nursing care of nausea and vomiting occurred in interventional treatment for acute myocardial infarction[J].journal interventional radiology,2011,(03):913.
[9]王海亭,蒋忠仆,周 毅,等. 透视引导下鱼肝油酸钠泡沫硬化剂治疗下肢静脉曲张30例[J].介入放射学杂志,2011,(11):905.
 WANG Hai-ting,JIANG Zhong-pu,ZHOU Yi,et al.Fluoroscopically-guided foam sclerotherapy with sodium morrhuate for the treatment of lower extremity varices[J].journal interventional radiology,2011,(03):905.
[10]杜 鲲,管 生,胡小波,等. 原发性肝癌TACE术后完全缓解病灶磁共振 ADC值可重复性及一致性研究[J].介入放射学杂志,2011,(11):867.
 DU Kun,GUAN Sheng,HU Xiao-bo,et al.Magnetic resonance apparent diffusion coefficient values of the completely remitted lesions of primary hepatocellular carcinoma after TACE: a study of their repeatability and consistency[J].journal interventional radiology,2011,(03):867.
[11]程洪涛,郭晨阳,黎海亮,等.TACE联合射频消融治疗原发性肝癌疗效的影响因素分析[J].介入放射学杂志,2012,(03):216.
 ,,et al.TACE combined with CTguided percutaneous radiofrequency ablation for the treatment of primary hepatocellular carcinomas: an analysis of factors affecting the therapeutic result [J].journal interventional radiology,2012,(03):216.
[12]姚红响,陈根生,诸葛英,等.肝动脉化疗栓塞联合CT引导射频消融序贯治疗中小肝癌的临床应用[J].介入放射学杂志,2012,(04):301.
 ,,et al.Sequential treatment with TACE and CTguided RFA for small and moderate sized HCC [J].journal interventional radiology,2012,(03):301.
[13]姚全军,胡鸿涛,黎海亮,等.C臂CT成像在乏血供原发性肝癌诊疗中的临床应用[J].介入放射学杂志,2012,(04):305.
 ,,et al.The clinical application of C arm CT imaging in diagnosing and treating hypovascular primary hepatic carcinomas [J].journal interventional radiology,2012,(03):305.
[14]高 嵩,朱旭,杨仁杰,等. TACE联合奥沙利铂、氟尿嘧啶、亚叶酸钙肝动脉化疗治疗中晚期原发性肝癌[J].介入放射学杂志,2012,(05):377.
 ,,et al. TACE combined with hepatic arterial infusion chemotherapy using oxaliplatin, 5fluorouracil and folinic acid for intermediate and advanced hepatocellular carcinomas[J].journal interventional radiology,2012,(03):377.
[15]刘 昕,吕维富,鲁 东,等. 动脉介入栓塞治疗肝癌破裂出血[J].介入放射学杂志,2012,(07):586.
 LIU Xin,LV Wei- fu,LU Dong,et al. Interventional treatment of hepatic bleeding due to spontaneous rupture of hepatocellular carcinoma[J].journal interventional radiology,2012,(03):586.
[16]张志良,杨学东,温阿明,等. 经动脉化疗栓塞联合伽玛刀治疗原发性肝癌的疗效评价[J].介入放射学杂志,2012,(07):596.
 ZHANG Zhi- liang,YANG Xue- dong,WEN A-ming,et al. Evaluation of TACE combined with gamma?蛳 knife radiotherapy for primary hepatocellular carcinoma[J].journal interventional radiology,2012,(03):596.
[17]赵许亚,周 石.TACE联合经皮瘤内注射碘油吡柔比星乳剂治疗中晚期肝癌疗效分析[J].介入放射学杂志,2012,(08):675.
 ZHAO Xu- ya,ZHOU Shi.. Transcatheter artery chemoembolization combined with percutaneous intratumoral injection of Lipiodol emulsion of pirarubicin for advanced hepatocellular carcinomas: an analysis of clinical efficacy[J].journal interventional radiology,2012,(03):675.
[18]王少雷,李 森,魏 宏,等.奥沙利铂与吡喃阿霉素介入治疗原发性肝癌的比较研究[J].介入放射学杂志,2012,(09):738.
 WANG Shao- lei,LI Sen,WEI Hong,et al. Interventional chemoembolization therapy of primary hepatocellular carcinoma: a comparative study between oxaliplatin and therarubicin[J].journal interventional radiology,2012,(03):738.
[19]李虎子,郭 志,王海涛,等.肝细胞癌患者TACE后外周血调节性T细胞水平对预后的影响[J].介入放射学杂志,2012,(12):998.
 LI Hu? zi,GUO Zhi,WANG Hai? tao,et al. The effect of regulatory T cells level in peripheral blood on the prognosis in HCC patients after TACE [J].journal interventional radiology,2012,(03):998.
[20]陶超超,张鸿文,吴纪瑞. 原发性肝癌TACE术后肺部炎症的影像表现及原因分析[J].介入放射学杂志,2012,(12):1038.
 TAO Chao? chao,ZHANG Hong? wen,WU Ji? rui.. Pulmonary inflammation occurring after TACE for primary hepatocellular carcinoma: its imaging features and an analysis of its causes[J].journal interventional radiology,2012,(03):1038.

备注/Memo

备注/Memo:
 (收稿日期:20110611)
更新日期/Last Update: