[1]赵晓阳,曹会存,李天晓,等. TACE联合RFA治疗胆管癌根治性切除术后肝转移11例[J].介入放射学杂志,2013,(11):954-958.
　ZHAO Xiao? yang,CAO Hui? cun,LI Tian? xiao,et al. TACE combined with RFA for the treatment of hepatic metastases after radical resection of cholangiocarcinoma： report of 11 cases[J].journal interventional radiology,2013,(11):954-958.
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 TACE联合RFA治疗胆管癌根治性切除术后肝转移11例 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年11期
页码:
954-958
栏目:
临床研究
出版日期:
2013-11-15

文章信息/Info

Title:
 TACE combined with RFA for the treatment of hepatic metastases after radical resection of cholangiocarcinoma： report of 11 cases
作者:
 赵晓阳;  曹会存;  李天晓;  王振豫;  曹广劭;  刘 健;  王玉丹;  刘建文
Author(s):
 ZHAO Xiao?蛳 yang;  CAO Hui?蛳 cun;  LI Tian?蛳 xiao;  WANG Zhen?蛳 yu;  CAO Guang?蛳 shao;  LIU Jian;  WANG Yu?蛳 dan;  LIU Jian?蛳 wen.
 Department of Interventional Radiology， Henan Provincial People’s Hospital， Zhengzhou University， Zhengzhou， Henan Province 450003， China
关键词:
 ; 【关键词】 胆管癌;  肝转移;  射频消融;  化疗栓塞
文献标志码:
A
摘要:
 【摘要】 目的 探讨胆管癌根治性切除术后肝转移经导管肝动脉化疗栓塞（TACE）联合射频消融（RFA）治疗的疗效和安全性。方法 收集2009年5月至2012年5月11例胆管癌根治性切除术后肝转移患者，先在DSA下行TACE，1个月后根据复查情况在CT引导下行RFA。术后定期进行CT、血常规、肝功能等检查，观察并记录患者病灶变化情况、术后并发症及生存期等。结果 所有患者均成功完成TACE和RFA，并且在1次或多次RFA治疗后转移病灶完全坏死，发生肿瘤局部进展的中位时间为4.5个月，自首次发现肝转移中位生存时间为13个月。术后常见不良反应为肝区疼痛、发热等，均给予对症处理后好转。仅2例患者复查出现肝脓肿，白细胞升高，给予抽吸引流及抗生素治疗后好转。观察期内未出现由手术或手术并发症直接致死病例。结论 TACE联合RFA能够有效的控制胆管癌根治性切除术后肝转移患者肝内病灶的进展，延长患者生存期，提高患者生存质量。

参考文献/References:

 ［1］ Vasilieva LE， Papadhimitriou SI， Dourakis SP. Modern diagnostic approaches to cholangiocarcinoma［J］. Hepatobiliary Pancreat Dis Int， 2012， 11： 349 ?蛳 359.
［2］ Taylor I， Mullee MA， Campbell MJ. Prognostic index for the development of liver metastases in patients with colorectal Cancer［J］. Br J Surg， 1990， 77： 499 ?蛳 501.
［3］ Woo SM， Ryu JK， Lee SH， et al. Recurrence and prognostic factors of ampullary carcinoma after radical resection： comparison with distal extrahepatic cholangiocarcinoma［J］. Ann Surg Oncol， 2007， 14： 3195 ?蛳 3201.
［4］ Meloni MF， Andreano A， Laeseke PF， et al. Breast cancer liver metastases： US?蛳 guided percutaneous radiofrequency ablation?蛳 intermediate and long?蛳 term survival rates［J］. Radiology， 2009， 253： 861 ?蛳 869.
［5］ Wang YH， Liu JF， Li F， et al. Radiofrequency ablation combined with transarterial chemoembolization for unresectable primary liver Cancer［J］. Chin Med J （Engl）， 2009， 122： 889 ?蛳 894.
［6］ Nimura Y， Kamiya J， Kondo S， et al. Aggressive preoperative management and extended surgery for hilar cholangiocarcinoma： Nagoya experience［J］. J Hepatobiliary Pancreat Surg， 2000， 7： 155 ?蛳 162.
［7］ DeOliveira ML， Cunningham SC， Cameron JL， et al. Cholangiocarcinoma： thirty?蛳 one?蛳 year experience with 564 patients at a single institution［J］. Ann Surg， 2007， 245： 755 ?蛳 762.
［8］ Gwak HK， Kim WC， Kim HJ， et al. Extrahepatic bile duct cancers： surgery alone versus surgery plus postoperative radiation therapy［J］. Int J Radiat Oncol Biol Phys， 2010， 78： 194 ?蛳 198.
［9］ Ksienski D， Woods R， Speers C， et al. Patterns of referral and resection among patients with liver?蛳 only metastatic colorectal Cancer （MCRC）［J］. Ann Surg Oncol， 2010， 17： 3085 ?蛳 3093.
［10］ Pockaj BA， Wasif N， Dueck AC， et al. Metastasectomy and surgical resection of the primary tumor in patients with stage IV breast Cancer： time for a second look？［J］. Ann Surg Oncol， 2010， 17： 2419 ?蛳 2426.
［11］ Mcgahan JP， Browning PD， Brock JM， et al. Hepatic ablation using radiofrequency electrocautery［J］. Invest Radiol， 1990， 25： 267 ?蛳 270.
［12］ Meloni MF， Andreano A， Laeseke PF， et al. Breast Cancer liver metastases： US?蛳 guided percutaneous radiofrequency ablation?蛳 intermediate and long?蛳 term survival rates［J］. Radiology， 2009， 253： 861 ?蛳 869.
［13］ Amersi FF， McElrath?蛳 Garza A， Ahmad A， et al. Long?蛳 term survival after radiofrequency ablation of complex unresectable liver tumors［J］. Arch Surg， 2006， 141： 581 ?蛳 587.
［14］ 宋 莉， 佟小强， 王 健， 等． 碘化油肝动脉柃塞对灌注型射频消融的影响： 实验研究［J］． 中国介入影像与治疗学， 2010， 7： 181 ?蛳 184．
［15］ Yamakado K， Nakatsuka A， Ohmori S， et al. Radiofrequency ablation combined with chemoembolization in hepatocellular carcinoma： treatment response based on tumor size and morphology［J］. J Vasc Interv Radiol， 2002， 13： 1225 ?蛳 1232.
［16］ 程洪涛， 郭晨阳， 黎海亮， 等． TACE联合射频消融治疗原发性肝癌疗效的影响因素分析［J］． 介入放射学杂志， 2012， 21： 216 ?蛳 219．
［17］ Park SY， Kim JH， Won HJ， et al. Radiofrequency ablation of hepatic metastases after curative resection of extrahepatic cholangiocarcinoma［J］. Am J Roentgenol， 2011， 197： 1129 ?蛳 1134.
［18］ Kim JH， Won HJ， Shin YM， et al. Radiofrequency ablation for the treatment of primary intrahepatic cholangiocarcinoma［J］. AJR Am J Roentgenol， 2011， 196： 205 ?蛳 209.
［19］ Gillams AR， Lees WR. Five?蛳 year survival following radiofre?蛳 quency ablation of small， solitary， hepatic colorectal metastases［J］. J Vasc Interv Radiol， 2008， 19： 712 ?蛳 717.
［20］ Elias D， Di Pietroantonio D， Gachot B， et al. Liver abscess after radiofrequency ablation of tumors in patients with a biliary tract procedure［J］. Gastroenterol Clin Biol， 2006， 30： 823 ?蛳 827. 

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备注/Memo

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 （收稿日期：２０１3-０5-16）
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