[1]王少雷,李 森,魏 宏,等.奥沙利铂与吡喃阿霉素介入治疗原发性肝癌的比较研究[J].介入放射学杂志,2012,(09):738-742.
 WANG Shao- lei,LI Sen,WEI Hong,et al. Interventional chemoembolization therapy of primary hepatocellular carcinoma: a comparative study between oxaliplatin and therarubicin[J].journal interventional radiology,2012,(09):738-742.
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奥沙利铂与吡喃阿霉素介入治疗原发性肝癌的比较研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年09期
页码:
738-742
栏目:
肿瘤介入
出版日期:
2012-09-30

文章信息/Info

Title:
 Interventional chemoembolization therapy of primary hepatocellular carcinoma: a comparative study between oxaliplatin and therarubicin
作者:
 王少雷 李 森 魏 宏 华 阳 刘德华
Author(s):
 WANG Shao- lei LI Sen WEI Hong HUA Yang LIU De- hua.
 Department of Medical Imaging, Liaoning Provincial Tumor Hospital, Shenyang, Liaoning Province 110042, China
关键词:
 【关键词】 原发性肝癌 奥沙利铂 吡喃阿霉素 介入治疗
文献标志码:
A
摘要:
 【摘要】 目的 评价并比较奥沙利铂与吡喃阿霉素介入治疗原发性肝癌的疗效及安全性。方法 分别以奥沙利铂和吡喃阿霉素为主的药物组合灌注栓塞治疗原发性肝癌。评价两组病例的有效率、疾病控制率、肿瘤标志物下降率、临床症状改善率、疾病进展时间、不良反应发生率以判断疗效及安全性。通过两组中疾病进展时间超过12个月的患者的比较判断影响介入治疗远期疗效的因素。结果 奥沙利铂组比吡喃阿霉素组的治疗有效率高,中位疾病无进展时间长,差异有统计学意义(P < 0.05)。病灶有无包膜、门静脉受累、术后合并应用抗癌药物对介入治疗的远期疗效有影响(P < 0.05)。结论 使用奥沙利铂介入治疗原发性肝癌安全、有效,可以提高治疗有效率及疾病无进展时间。但对于远期疗效的影响与吡喃阿霉素没有统计学差异。

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备注/Memo

备注/Memo:
 (收稿日期:2012-06-04)
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