[1]罗剑钧,王建华,刘清欣,等.微球联合碘油栓塞治疗肝癌的初步经验[J].介入放射学杂志,2007,(03):162.
　LUO Jian-jun,WANG Jian-hua,LIU Qing-xin,et al.Preliminary experience of HCC treated by embolization of microspheres combined with lipiodol[J].journal interventional radiology,2007,(03):162.
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微球联合碘油栓塞治疗肝癌的初步经验()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年03期
页码:
162
栏目:
肿瘤介入
出版日期:
2007-03-15

文章信息/Info

Title:
Preliminary experience of HCC treated by embolization of microspheres combined with lipiodol
作者:
罗剑钧; 王建华; 刘清欣; 等
２０００３２上海复旦大学附属中山医院放射科
Author(s):
LUO Jian-jun; WANG Jian-hua; LIU Qing-xin; CHEN Yi; YAN Zhi-ping．
Department of Radiology，Zhongshan Hospital，Fudan University，Shanghai２０００３２，China
关键词:
肝肿瘤; 栓塞; 微球
分类号:
R７３５.７
文献标志码:
A
摘要:
目的研究采用微球联合碘油作为栓塞剂治疗肝癌的安全性及疗效。方法对肝癌患者行经动脉化疗栓塞（TACE）治疗时除使用化疗药物外，选用直径３００～５００μm的微球１～２ml及碘油１０～２０ml作为栓塞剂。分别观察患者术前、术后肝功能、血清甲胎蛋白（AFP）水平、肿瘤的改变情况及栓塞相关并发症。结果３６例原发性肝癌患者入选本组研究。TACE术后患者黄疸指数、丙氨酸转氨酶和碱性磷酸酶均有不同程度升高，血清白蛋白、AFP水平明显降低；肿瘤不同程度坏死、缩小明显（P＜０．０５）。结论在肝癌介入治疗中，使用微球联合碘油作为栓塞剂，疗效明显；但可造成一定程度的肝功能损害，应注意栓塞剂的用量及肝功能保护。

参考文献/References:

［１］黄洁夫，李绍强，梁力建．肝动脉化疗栓塞在原发性肝癌治疗中的地位［J］．中华肝胆外科杂志，２０００，６：３-６．
［２］梁力建，张继红．肝动脉栓塞术在肝癌治疗中的临床应用及评价［J］．中国实用外科杂志，２００４，８：５０４-５０６．
［３］吴汉平，冯敢生．肝癌介入治疗的现状与展望［J］．临床放射学杂志，２００５，２４：２７３-２７６．
［４］Doppman JL，Girton M，Kahn ER．Proximal versus peripheral hepatica artery embolization experimental study in monkeys［J］．Radiology，１９７８，１２８：５７７-５８８．
［５］Brown KT，Nevins AB，Getrajdman GI，et al．Particle emboliza-tion for hepatocellular carcinoma［J］．J Vasc Interv Radiol，１９９８，５：８２２-８２８．

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备注/Memo

备注/Memo:
收稿日期：２００６-１２-１８
更新日期/Last Update: 2007-03-15