[1]赵林,石建成,刘增品,等.改良溶栓方案治疗静脉窦血栓形成[J].介入放射学杂志,2009,(03):167.
　ZHAO Lin,SHI Jiancheng,LIU Zengpin,et al.A modified thrombolytic scheme for the treatment of cerebral venous sinus thrombosis[J].journal interventional radiology,2009,(03):167.
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改良溶栓方案治疗静脉窦血栓形成()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2009年03期
页码:
167
栏目:
神经介入
出版日期:
2009-03-15

文章信息/Info

Title:
A modified thrombolytic scheme for the treatment of cerebral venous sinus thrombosis
作者:
赵林; 石建成; 刘增品; 等
０５００００石家庄河北医科大学第二医院医学影像科（赵林、石建成、刘增品、李林芳、王铁刚、周存和）；神经内科（王志红）
Author(s):
ZHAO Lin; SHI Jian－cheng; LIU Zeng－pin; LI Lin－fang; WANG Zhi－hong; WANG Tie－gang; ZHOU Cun－he．
Department of Radiology，the Second Hospital，Hebei Medical University，Shijiazhuang０５００００，China
关键词:
静脉窦; 溶栓; 介入; 尿激酶; 微量
分类号:
R７４３
文献标志码:
A
摘要:
目的探讨改良溶栓方案（最低静脉窦内微量持续泵点尿激酶１０万u／２４h）治疗脑静脉窦血栓形成的疗效和安全性。方法对２１例患者（合并出血性梗死５例，其中病史超过１个月２例，超过３个月１例）进行机械性破栓、静脉窦内留置微导管行最低量尿激酶１０万u／２４h静脉窦直接泵点滴４８～９６h治疗。术后积极治疗原发病，抗凝治疗６个月。术后随访６～１２个月，平均１０个月。结果２１例脑静脉窦血栓形成患者，脑静脉窦均获得再通（其中１２例患者应用尿激酶１０万u／２４h效果良好，９例患者在应用尿激酶１０万u／２４h，４８h复查后增量至２５万u／２４h），无一例并发或加重脑出血，预后良好。结论改良溶栓方案可有效治疗脑静脉窦血栓形成，有效规避了大量应用溶栓药物的问题，在达到同样疗效情况下更为安全。

参考文献/References:

［１］中华医学会神经外科分会，中国医师协会神经外科分会，中国医师协会神经内科分会．介入神经放射诊断治疗规范（修订稿）［J］．中国脑血管病杂志，２００５，２：４７６－４８０．
［２］李宝民，李生．出血性脑静脉窦血栓的血管内治疗［J］．介入放射学杂志，２００４，１３：１２９－１３０．
［３］吉训明，凌峰，缪中荣，等．颅内静脉窦血栓形成的血管内治疗［J］．中国脑血管病杂志，２００４，１：１００－１０５．
［４］张昱，卢明鸥．颅内静脉窦血栓形成的影像学诊断［J］．中国实用内科杂志，２００５

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备注/Memo

备注/Memo:
收稿日期：２００８－０９－２３
更新日期/Last Update: 2009-03-15