[1]吴曦,刘建民,黄清海,等.第一代Matrix弹簧圈治疗颅内动脉瘤的安全性及中长期随访结果分析[J].介入放射学杂志,2008,(06):384.
　WU Xi,LIU Jianmin,HUANG Qinghai,et al.Middle and long－term follow－up of intracranial aneurysms treated with Matrix detachable coils[J].J Intervent Med,2008,(06):384.
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第一代Matrix弹簧圈治疗颅内动脉瘤的安全性及中长期随访结果分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年06期
页码:
384
栏目:
神经介入
出版日期:
2008-06-15

文章信息/Info

Title:
Middle and long－term follow－up of intracranial aneurysms treated with Matrix detachable coils
作者:
吴曦; 刘建民; 黄清海; 等
２００４３３上海第二军医大学长海医院神经科中心
Author(s):
WU Xi ; LIU Jian－min; HUANG Qing－hai; XU Yi
Departm ent of Neurosurgery，Changhai Hospital of the Second Military Medical University，Shanghai２００４３３，China
关键词:
Matrix弹簧圈; 颅内动脉瘤; 颅内支架
分类号:
R７４３.４
文献标志码:
A
摘要:
目的分析第一代Matrix可吸收聚合物涂层弹簧圈（简称Matrix）治疗颅内动脉瘤的安全性，及中、长期随访结果的影响因素。方法回顾性研究，本中心２００３年５月至２００５年７月７５例使用Matrix栓塞颅内动脉瘤患者（７９枚动脉瘤）。其中造影复查患者３４例（３５枚动脉瘤），平均随访时间１２．５个月。根据复查结果对年龄、性别、动脉瘤最大径、瘤颈宽度、使用支架辅助、Matrix长度比例进行COX模型分析。结果Matrix相关的手术并发症率为１３．３％，使用Matrix术后动脉瘤总复发率为１１．４％，辅助支架治疗的大型动脉瘤的复发率为４０％，未致密栓塞的动脉瘤中６１．１％发生进一步栓塞。无统计学结果可证明年龄、性别、动脉瘤最大径、瘤颈宽度、支架辅助、Matrix占栓塞弹簧圈长度比例等因素影响Matrix栓塞动脉瘤的中长期预后。结论Matrix治疗颅内动脉瘤安全、有效，结合支架辅助技术可能会降低大型动脉瘤的复发率。Matrix弹簧圈有促进动脉瘤愈合的倾向，建议尽可能改善动脉瘤的血流动力学状况，此举将有利于动脉瘤长期愈后。Matrix弹簧圈的长期确切效果有待进一步随访观察及进行大样本的随机对照研究。

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备注/Memo

备注/Memo:
收稿日期：２００８－０２－０４
更新日期/Last Update: 2008-06-15