[1]段 林,何艳艳,李天晓,等.涂布镍钛合金表面的人血管内皮细胞生长因子重组质粒转染初步研究[J].介入放射学杂志,2022,31(05):476-479.
 DUAN Lin,HE Yanyan,LI Tianxiao,et al.Preliminary study on human VEGF transfected by recombinant plasmid coated with nickel-titanium alloy[J].journal interventional radiology,2022,31(05):476-479.
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涂布镍钛合金表面的人血管内皮细胞生长因子重组质粒转染初步研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年05
页码:
476-479
栏目:
实验研究
出版日期:
2022-07-19

文章信息/Info

Title:
Preliminary study on human VEGF transfected by recombinant plasmid coated with nickel-titanium alloy
作者:
段 林 何艳艳 李天晓 陈 松 贺迎坤 吴海刚 卢韬源
Author(s):
DUAN Lin HE Yanyan LI Tianxiao CHEN Song HE Yingkun WU Haigang LU Taoyuan.
Stroke center,People’s Hospital of Henan University(Henan Provincial People’s Hospital), Zhengzhou, Henan Province 450003, China
关键词:
【关键词】 血管内皮细胞生长因子 质粒 基质胶 镍钛合金 转染
文献标志码:
A
摘要:
【摘要】 目的 制备含重组质粒涂层,提高介入医疗器材生物相容性和耐腐蚀性,降低再狭窄率。 方法 将人脐静脉内皮细胞分别接种到涂布基质胶+黏连蛋白和基质胶+黏连蛋白+人血管内皮细胞生长因子(VEGF)重组质粒的镍钛合金丝上,37℃培养48 h后用正置荧光显微镜观测。结果 基质胶+黏连蛋白包被的镍钛合金丝表面细胞无绿色荧光,含人VEGF重组质粒包被的镍钛合金丝表面细胞有绿色荧光,表明人VEGF重组质粒转染成功。结论 人VEGF重组质粒转染成功,此种涂层具有可行性,可用于介入医疗器材表面改性。

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备注/Memo

备注/Memo:
 (收稿日期:2021- 04- 25)
(本文编辑:边 佶)
更新日期/Last Update: 2022-07-19