[1]饶 伟,周 超,王士强.连续星状神经节阻滞对颅内动脉瘤介入术后脑血管痉挛的治疗作用 [J].介入放射学杂志,2019,28(01):15-18.
 RAO Wei,ZHOU Chao,WANG Shiqiang.Therapeutic effect of continuous stellate ganglion block on cerebral vasospasm after interventional treatment of intracranial aneurysms [J].journal interventional radiology,2019,28(01):15-18.
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连续星状神经节阻滞对颅内动脉瘤介入术后脑血管痉挛的治疗作用
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年01期
页码:
15-18
栏目:
神经介入
出版日期:
2019-01-25

文章信息/Info

Title:
Therapeutic effect of continuous stellate ganglion block on cerebral vasospasm after interventional treatment of intracranial aneurysms
作者:
饶 伟 周 超 王士强
Author(s):
RAO Wei ZHOU Chao WANG Shiqiang
Department of Neurology, Jiangxi Provincial People’s Hospital, Nanchang, Jiangxi Province 330006, China
关键词:
【关键词】 连续星状神经节阻滞 颅内动脉瘤 脑血管痉挛 血浆内皮素
文献标志码:
A
摘要:
【摘要】 目的 探讨星状神经节阻滞(SGB)治疗颅内动脉瘤介入术后患者脑血管痉挛的效果及对血浆内皮素(ET)- 1的影响。方法 选取2016年3月至2017年3月收治的动脉瘤性蛛网膜下腔出血需行全身麻醉下介入治疗患者72例,随机分为对照组(n=36,常规气管内插管,静息复合维持麻醉)和观察组(n=36,常规基础上持续用0.25%罗哌卡因10 mL行左侧SGB,连续3 d)。经颅多普勒(TCD)技术监测两组患者治疗前(T0)及治疗后2 h(T1)、6 h(T2)、1 d(T3)、3 d(T4)大脑前动脉(ACA)、大脑中动脉(MCA)和大脑后动脉(PCA)血流速度,记录两组患者及不同Hunt- Hess分级患者脑血管痉挛和脑缺血发生情况,放射免疫法检测T0~T4时点血浆ET- 1水平,观察治疗期间并发症发生情况。结果 两组治疗后ACA、MCA、PCA平均血流速度均显著降低,观察组改善均高于对照组(P<0.05);血浆ET- 1水平分别在对照组T1~4时点,观察组T3、T4时点升高(P<0.05),T1~4时点观察组均低于对照组(P<0.05);治疗期间观察组脑血管痉挛和脑缺血总发生率(13.9%)显著低于对照组(61.1%)(P<0.05);对照组Hunt- HessⅠ级、Ⅱ级脑血管痉挛和脑缺血发生率均高于观察组(P<0.05);术后观察组并发症发生率为8.3%(3/36),显著低于对照组(30.6%,11/36)(P<0.05)。结论 连续SGB可有效降低颅内动脉瘤介入术后脑血管痉挛发生率及血浆ET- 1水平,较之常规介入术式更安全有效。

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备注/Memo

备注/Memo:
(收稿日期:2018-03-06)
(本文编辑:边 佶)
更新日期/Last Update: 2019-01-21