[1]丁爱萍,李子祥,王松,等.动脉化疗治疗头颈部恶性肿瘤的临床研究[J].介入放射学杂志,2007,(11):743.
 DING Ai-ping,LI Zi-xiang,WANG Song,et al.Clinical study on arterial infusion chemotherapy for the head and neck malignant tumors[J].journal interventional radiology,2007,(11):743.
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动脉化疗治疗头颈部恶性肿瘤的临床研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年11期
页码:
743
栏目:
肿瘤介入
出版日期:
2007-11-15

文章信息/Info

Title:
Clinical study on arterial infusion chemotherapy for the head and neck malignant tumors
作者:
丁爱萍李子祥王松
266003青岛大学医学院附属医院肿瘤科
Author(s):
DING Ai-pingLI Zi-xiangWANG SongSUN Cheng-jianWANG Yan-qingLI Ning-yi
Department of Oncology,The Hospital Affiliated to Medical College of Qingdao University Qingdao266003,China
关键词:
动脉灌注化疗/栓塞恶性肿瘤头颈部
分类号:
R739.8
文献标志码:
A
摘要:
目的研究超选择性动脉介入灌注化疗和栓塞治疗头颈部恶性肿瘤的价值。方法31例头颈部恶性肿瘤患者根据肿瘤部位分别行超选择性舌动脉、颌内动脉、面动脉介入灌注化疗,其中明胶海绵颗粒栓塞11例。化疗药物采用顺铂(CDDP)、5-FU、甲氨碟呤(MTX)、表阿霉素(EPI)等2~3种联合应用。结果31例头颈部恶性肿瘤选择性动脉插管化疗和栓塞,半月后肿瘤体积缩小21例(占67.8%);肿瘤溃疡面缩小8例(占25.8%);未见明显变化2例。组织学疗效:19例介入治疗后接受手术,10例栓塞后的手术标本均为显效,栓塞标本近栓塞的血管处坏死程度重;9例未栓塞标本为有效。19例手术标本病理观察有效率94%。术中见肿瘤缩小,边界清楚,出血减少。19例术后目前仍生存15例(占78.9%),存活时间1~7.5年。结论术前超选择性动脉插管化疗栓塞对头颈部恶性肿瘤有较好的临床应用价值。

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备注/Memo

备注/Memo:
收稿日期:2007-06-01
更新日期/Last Update: 2007-11-15