[1]孙昊,李晓光,金征宇,等.经导管双侧髂内动脉灌注化疗治疗浸润性膀胱癌[J].介入放射学杂志,2010,(06):454.
 SUN Hao,LI Xiaoguang,JIN Zhengyu,et al.Transcatheter bilateral iliac arterial perfusion chemotherapy for the treatment of invasive bladder cancer[J].journal interventional radiology,2010,(06):454.
点击复制

经导管双侧髂内动脉灌注化疗治疗浸润性膀胱癌()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年06期
页码:
454
栏目:
肿瘤介入
出版日期:
2010-06-15

文章信息/Info

Title:
Transcatheter bilateral iliac arterial perfusion chemotherapy for the treatment of invasive bladder cancer
作者:
孙昊李晓光金征宇
100730北京中国医学科学院、北京协和医院放射科
Author(s):
SUN HaoLI Xiao-guangJIN Zheng-yuYANG NingLIU WeiPAN JieZHANG Xiao-boSHI Hai-fengZHOU KangWANG Zhi-wei.
Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing100730,China
关键词:
浸润性膀胱癌经导管灌注化疗经尿道切除
分类号:
R737.14
文献标志码:
A
摘要:
目的评价经导管双侧髂内动脉灌注化疗治疗膀胱癌的疗效及安全性。方法2008年6月至2009年12月,对23例浸润性膀胱癌患者行50例次经导管双侧髂内动脉灌注化疗,化疗药物为吉西他滨和顺铂。结果全部患者双侧髂内动脉插管均成功,术后不良反应包括发热4例次(8%),恶心、呕吐15例次(30%),厌食5例次(10%),穿刺点血肿4例次(8%),白细胞降低(<3×10 9 /L)1例次(2%)。经导管灌注化疗后,完全缓解(CR)2例(8.7%),部分缓解(PR)20例(87.0%),病情稳定(SD)1例(4.3%)。PR患者瘤体明显缩小,接受经尿道膀胱肿瘤电切术。全部病例随访3~12个月,平均5个月。肿瘤复发3例(13.0%),再次行经尿道膀胱肿瘤电切术。结论经导管双侧髂内动脉灌注化疗治疗浸润性膀胱癌有效、安全。

参考文献/References:

[1]汤钊猷.现代肿瘤学[M].上海:上海医科大学出版社,1993:900-909.
[2]Sternberg CN,Pansadoro V,Calabro F,et al.Can patient selection for bladder preservation be based on response to chemotherapy﹖[J]Cancer,2003,97:1644-1652.
[3]Rdel C,Grabenbauer GG,Kühn R,et al.Combined-modality treatment and selective organ preservation in invasive bladder cancer:long-term results[J].J Clin Oncol,2002,20:3061-3071.
[4]Shipley WU,Kaufman DS,Lane SC,et al.Selective bladder preservation by ombined modality protocol treatment :long-term outcomes of190patients with invasive bladder cancer[J].Urology,2002,60:62-67.
[5]高鹏,丁强,方祖军,等.新辅助介入化疗后经尿道切除治疗浸润性膀胱癌[J].临床泌尿外科杂志,2007,22:664-665,668.
[6]许彪,文斌,刘惕生,等.介入联合手术治疗浸润性膀胱癌[J].介入放射学杂志,2007,16:35-38.
[7]申东峰,谢春明.化疗栓塞与化疗灌注在中晚期膀胱癌治疗中的对照研究[J].临床放射学杂志,2007,26:1265-1268.
[8]周俊,袁建华,杨文铎,等.浸润性膀胱癌术前动脉化疗的疗效分析[J].中华泌尿外科杂志,2003,24:542-544.
[9]Juffs HG,Moore MJ ,Tannock IF.The role of systemic chemotherapy in the management of muscle-invasive bladder cancer[J].Lancet Oncol,2002,3:738-747.
[10]黄埔处,王良圣.经动脉灌注区域化疗治疗浸润性膀胱癌[J].国外医学泌尿系统分册,2000,20:226-227.
[11]姚绍鑫,崔慧先,崔进国.盆腔肿瘤介入治疗的应用解剖研究[J].介入放射学杂志,2007,16:29-31.
[12]von der Maase H,Hansen SW,Roberts JT.et al.Gemcitabine and cisplatin versus methotrexate,vinblastine,doxorubicin,and cisplatin in advanced or metastatic bladder cancer:results of a large,randomized,multinational,multicenter,phaseⅢstudy[J].J Clin Oncol,2000,18:3068-3077.

相似文献/References:

[1]贺洪德,贺晶,罗中华,等.肝动脉化疗栓塞联合门静脉栓塞治疗中晚期肝癌的疗效评价[J].介入放射学杂志,2010,(03):191.
 HE Hongde,HE Jing,LUO Zhonghua,et al.Evaluation of the therapeutic effect of hepatic arterial chemoembolization combined with portal chemoembolization for advanced hepatic carcinomas[J].journal interventional radiology,2010,(06):191.
[2]宗刚军,白元,吴弘,等.经导管肺动脉瓣膜植入的实验研究[J].介入放射学杂志,2007,(09):623.
 ZONG Gang-jun,BAI Yuan,WU Hong,et al.Experiment study of open transcatheter replacement of pulmonary valves[J].journal interventional radiology,2007,(06):623.
[3]陈 翔,王飞宇,谭洪文,等.经导管建立大动物急性主动脉瓣关闭不全模型的实验研究[J].介入放射学杂志,2014,(07):615.
 CHEN Xiang,WANG Fei- yu,TAN Hong- wen,et al.Transcatheter establishment of an animal model with acute aortic valve regurgitation: an experimental study[J].journal interventional radiology,2014,(06):615.

备注/Memo

备注/Memo:
收稿日期:2010-03-29
更新日期/Last Update: 2010-06-15