[1]刘文波,唐 垚,何艳艳,等.球囊成形和强化药物治疗合并低灌注的颅内动脉粥样硬化性狭窄临床效果[J].介入放射学杂志,2023,32(05):459-464.
 LIU Wenbo,TANG Yao,HE Yanyan,et al.Balloon dilatation angioplasty versus intensive medication in treating intracranial atherosclerotic stenosis complicated by hypoperfusion: comparison of clinical effect[J].journal interventional radiology,2023,32(05):459-464.
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球囊成形和强化药物治疗合并低灌注的颅内动脉粥样硬化性狭窄临床效果(/HTML)

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年05
页码:
459-464
栏目:
临床研究
出版日期:
2023-05-30

文章信息/Info

Title:
Balloon dilatation angioplasty versus intensive medication in treating intracranial atherosclerotic stenosis complicated by hypoperfusion: comparison of clinical effect
作者:
刘文波 唐 垚 何艳艳 赵文利 姜卫剑 赵 耀 贺迎坤 李天晓
Author(s):
LIU Wenbo TANG Yao HE Yanyan ZHAO Wenli JIANG Weijian ZHAO Yao HE Yingkun LI Tianxiao.
Cerebrovascular Department of Interventional Center, People’s Hospital of Zhengzhou University(Henan Provincial People’s Hospital); Neurosurgery Department of Stroke Center; Henan Provincial Neurointerventional Engineering Research Center; Henan International Joint Laboratory of Cerebrovascular Disease; Henan Engineering Research Center of Cerebrovascular Intervention Innovation, Zhengzhou, Henan Province 450003, China
关键词:
【关键词】 颅内动脉粥样硬化性狭窄球囊扩张成形术强化药物治疗低灌注倾向性评分匹配
文献标志码:
A
摘要:
【摘要】 目的 对比球囊扩张成形术和强化药物治疗合并低灌注表现的颅内动脉粥样硬化性狭窄(ICAS)患者的临床效果。方法 回顾性纳入2019年1月至2021年6月郑州大学人民医院收治的139例合并低灌注表现的ICAS患者,依据临床治疗方式分为球囊组和药物组。采用倾向性评分匹配(PSM)法进行配对,得到新的两组患者。对比两组间终点事件发生情况,包括随访期任何类型同侧脑卒中、短暂性脑缺血发作和任何原因所致死亡。结果 PSM后选取68例匹配患者,球囊组和药物组各34例。中位随访25个月(6~36个月),药物组、球囊组30 d内终点事件发生率为分别为2.9%(1/34)、0(P=1.000),差异无统计学意义。截至末次随访,药物组终点事件发生率高于球囊组(14.7%比8.8%,OR=1.782,95%CI=0.390~8.132,P=0.707),但差异无统计学意义。结论 与强化药物治疗相比,球囊扩张成形术治疗合并低灌注表现的ICAS效果可能较好,但远期疗效仍需多中心、大样本、长随访周期的临床试验证明。

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备注/Memo

备注/Memo:
(收稿日期:2022-03-22)
(本文编辑:边 佶)
更新日期/Last Update: 2023-05-30