[1]沈 寻,王文蕾,秦怀海,等.Neuroform EZ支架辅助颅内动脉瘤栓塞后动脉内膜增生的动态演化规律[J].介入放射学杂志,2023,32(01):48-54.
 SHEN Xun,WANG Wenlei,QIN Huaihai,et al.The dynamic evolution of the arterial intimal hyperplasia after Neuroform EZ stent-assisted treatment of intracranial aneurysms[J].journal interventional radiology,2023,32(01):48-54.
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Neuroform EZ支架辅助颅内动脉瘤栓塞后动脉内膜增生的动态演化规律()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年01
页码:
48-54
栏目:
临床研究
出版日期:
2023-02-13

文章信息/Info

Title:
The dynamic evolution of the arterial intimal hyperplasia after Neuroform EZ stent-assisted treatment of intracranial aneurysms
作者:
沈 寻 王文蕾 秦怀海 郝伟丽 张学敬 高不郎
Author(s):
SHEN Xun WANG Wenlei QIN Huaihai HAO Weili ZHANG Xuejing GAO Bulang.
Department of Neurosurgery, Emergency General Hospital, Beijing 100028, China
关键词:
【关键词】颅内动脉瘤支架辅助栓塞载瘤动脉支架内狭窄Neuroform EZ支架
文献标志码:
A
摘要:
【摘要】 目的 对接受Neuroform EZ支架辅助栓塞治疗的颅内宽颈动脉瘤患者载瘤动脉直径进行准确测量,以明确载瘤动脉对支架植入的反应。方法 纳入87例患者100枚颅内未破裂动脉瘤,均行Neuroform EZ支架辅助栓塞治疗及高分辨率3D旋转血管造影。采用亚毫米级3D形态测量分析系统Amira成像软件对植入支架前后载瘤动脉直径和横截面积(CSA)进行测量和分析。结果 支架植入即刻与植入前相比,载瘤动脉D点直径(增大0.18 mm或16.0%)、E点直径(增大0.09 mm或3.2%)显著增大(均P<0.01)。初期血管造影随访中,与支架植入即刻相比,载瘤动脉平均直径在A点(缩小0.21 mm或5.7%)、B点(缩小0.50 mm或14.1%)、D点(缩小0.44 mm或14.0%)、E点(缩小0.29 mm或10.7%)显著缩小(均P<0.01)。末次血管造影随访中,支架内狭窄自行消失,血管直径恢复到支架植入即刻水平。载瘤动脉CSA百分比变化显示,支架植入4个月时开始下降,6个月时逐渐增大,直至恢复至植入即刻初始水平。结论 Neuroform EZ支架辅助栓塞颅内动脉瘤时支架植入段动脉会发生动态、可逆的内膜增生和再狭窄反应。该发现可用于支架直径选择和抗凝药物应用,以降低支架植入不良反应,提高疗效。

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备注/Memo

备注/Memo:
(收稿日期:2021-08-07)
(本文编辑:边 佶)  
更新日期/Last Update: 2023-02-13